ClinicalTrials.gov record

Terminated Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia: A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation

ClinicalTrials.gov ID: NCT06424236

Public ClinicalTrials.gov record NCT06424236. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 20, 2026, 6:43 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II/III Multicenter Randomized, Double-Blind, Placebo-Controlled Platform Trial of Potential Disease Modifying Therapies Utilizing Biomarker, Cognitive, and Clinical Endpoints in Dominantly Inherited Alzheimer's Disease

Study identification

NCT ID: NCT06424236
Recruitment status: Terminated
Study type: Interventional
Phase: Phase 2, Phase 3
Lead sponsor: Washington University School of Medicine; Other
Enrollment: 73 participants

Conditions and interventions

Conditions

Interventions

Gantenerumab Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 80 Years
Sex: All
Healthy volunteers: Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jun 2, 2020
Primary completion: Oct 5, 2023
Completion: Nov 12, 2023
Last update posted: Feb 3, 2025

2020 – 2023

United States locations

U.S. sites: 8
U.S. states: 8
U.S. cities: 8

Facility	City	State	ZIP	Site status
University of Alabama in Birmingham	Birmingham	Alabama	35294	—
University of California San Diego Medical Center	La Jolla	California	92037	—
Emory University	Atlanta	Georgia	30329	—
Indiana University School of Medicine	Indianapolis	Indiana	46202	—
Washington University in St. Louis	St Louis	Missouri	63110	—
University of Pittsburgh	Pittsburgh	Pennsylvania	15213	—
Butler Hospital	Providence	Rhode Island	02096	—
University of Washington	Seattle	Washington	98195	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06424236, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Feb 3, 2025 · Synced May 20, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06424236 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →