ClinicalTrials.gov record
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
ClinicalTrials.gov ID: NCT06430801
Public ClinicalTrials.gov record NCT06430801. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 5, 2026, 7:00 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Program to Evaluate the Efficacy and Safety of Tulisokibart in Participants With Moderately to Severely Active Crohn's Disease
Study identification
- NCT ID
- NCT06430801
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Merck Sharp & Dohme LLC
- Industry
- Enrollment
- 1,200 participants
Conditions and interventions
Conditions
Interventions
- IV Placebo Other
- IV Tulisokibart Drug
- SC Placebo Other
- SC Tulisokibart Drug
Other · Drug
Eligibility (public fields only)
- Age range
- 16 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 4, 2024
- Primary completion
- Oct 29, 2028
- Completion
- Nov 11, 2029
- Last update posted
- May 3, 2026
2024 – 2029
United States locations
- U.S. sites
- 87
- U.S. states
- 32
- U.S. cities
- 75
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Digestive Health Specialists ( Site 5064) | Dothan | Alabama | 36301 | Recruiting |
| Arizona Arthritis & Rheumatology Research, PC ( Site 5094) | Phoenix | Arizona | 85032 | Completed |
| GI Alliance - Sun City ( Site 5118) | Sun City | Arizona | 85351 | Recruiting |
| University of Arizona Clinical and Translational Sciences Research Center ( Site 5111) | Tucson | Arizona | 85724 | Recruiting |
| University of Arkansas for Medical Sciences ( Site 5147) | Little Rock | Arkansas | 72205 | Recruiting |
| Clinnova Research ( Site 5110) | Anaheim | California | 92805 | Recruiting |
| Southern California Research Center ( Site 5044) | Coronado | California | 92118 | Recruiting |
| Om Research LLC ( Site 5038) | Lancaster | California | 93534 | Recruiting |
| Cedars Sinai Medical Center ( Site 5080) | Los Angeles | California | 90048 | Recruiting |
| UCLA Clinical & Translational Research Center (CTRC) ( Site 5116) | Los Angeles | California | 90095 | Recruiting |
| University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 5128) | Orange | California | 92868 | Recruiting |
| Om Research LLC ( Site 5045) | Oxnard | California | 93030 | Recruiting |
| Clinical Applications Laboratories ( Site 5123) | San Diego | California | 92103 | Recruiting |
| Amicis Research Center ( Site 5055) | Valencia | California | 91355 | Active, not recruiting |
| University of Colorado Anschutz Medical Campus-Division of Gastroenterology and Hepatology ( Site 5026) | Aurora | Colorado | 80045 | Recruiting |
| Peak Gastroenterology Associates ( Site 5023) | Colorado Springs | Colorado | 80907 | Recruiting |
| South Denver Gastroenterology, PC ( Site 5132) | Englewood | Colorado | 80113 | Recruiting |
| Rocky Mountain Gastroenterology ( Site 5082) | Lakewood | Colorado | 80228 | Recruiting |
| Medical Research Center of Connecticut ( Site 5005) | Hamden | Connecticut | 06518 | Completed |
| Yale University School of Medicine-Digestive Disease ( Site 5019) | New Haven | Connecticut | 06510 | Recruiting |
| Emerson Clinical Research Institute ( Site 5051) | Washington D.C. | District of Columbia | 20009 | Recruiting |
| Gastroenterology Consultants of Clearwater ( Site 5052) | Clearwater | Florida | 33756 | Active, not recruiting |
| Covenant Metabolic Specialists, LLC ( Site 5150) | Fort Myers | Florida | 33912 | Recruiting |
| Nature Coast Clinical Research - Inverness ( Site 5042) | Inverness | Florida | 34452 | Recruiting |
| Atlantic Medical Research ( Site 5073) | Margate | Florida | 33063 | Recruiting |
| Sanchez Clinical Research ( Site 5144) | Miami | Florida | 33157 | Recruiting |
| AdventHealth Orlando ( Site 5131) | Orlando | Florida | 32803 | Recruiting |
| Endoscopic Research Inc ( Site 5061) | Orlando | Florida | 32803 | Recruiting |
| Orlando Health-Digestive Health Institute ( Site 5010) | Orlando | Florida | 32806 | Completed |
| USF Health Carol and Frank Morsani Center for Advanced Healthcare ( Site 5039) | Tampa | Florida | 33612 | Recruiting |
| Covenant Metabolic Specialists, LLC ( Site 5143) | University Park | Florida | 34201 | Recruiting |
| Morehouse School Of Medicine ( Site 5071) | Atlanta | Georgia | 30310 | Recruiting |
| Atlanta Center for Gastroenterology ( Site 5035) | Decatur | Georgia | 30033 | Completed |
| Gastroenterology Associates of Central Georgia ( Site 5048) | Macon | Georgia | 31201 | Recruiting |
| Eagle Clinical Research ( Site 5089) | Chicago | Illinois | 60621 | Completed |
| University of Chicago Medical Center ( Site 5066) | Chicago | Illinois | 60637 | Recruiting |
| Endeavor Health ( Site 5018) | Evanston | Illinois | 60201 | Recruiting |
| GI ALLIANCE - GURNEE ( Site 5003) | Gurnee | Illinois | 60031 | Recruiting |
| Indiana University Health University Hospital ( Site 5022) | Indianapolis | Indiana | 46202 | Recruiting |
| Iowa Digestive Disease Center ( Site 5007) | Clive | Iowa | 50325 | Recruiting |
| University of Kansas Medical Center ( Site 5091) | Kansas City | Kansas | 66160 | Recruiting |
| Cotton O'Neil Digestive Health Center ( Site 5033) | Topeka | Kansas | 66606 | Recruiting |
| University of Louisville Hospital ( Site 5120) | Louisville | Kentucky | 40202 | Recruiting |
| Southern Clinical Research ( Site 5095) | Zachary | Louisiana | 70791 | Completed |
| Walter Reed National Military Medical Center ( Site 5006) | Bethesda | Maryland | 20889 | Recruiting |
| Massachusetts General Hospital-Crohn's and Colitis Center ( Site 5037) | Boston | Massachusetts | 02114 | Recruiting |
| University of Michigan ( Site 5060) | Ann Arbor | Michigan | 48109 | Recruiting |
| Clinical Research Institute of Michigan, LLC ( Site 5002) | Clinton Township | Michigan | 48038 | Recruiting |
| Mayo Clinic in Rochester, Minnesota ( Site 5024) | Rochester | Minnesota | 55905 | Recruiting |
| Mid-America GI Clinical Research ( Site 5130) | Kansas City | Missouri | 64111 | Recruiting |
| BVL Research - Kansas ( Site 5099) | Liberty | Missouri | 64068 | Recruiting |
| Washington University School of Medicine ( Site 5058) | St Louis | Missouri | 63110 | Recruiting |
| HMH Justice Marie Garibaldi Medical Plaza ( Site 5072) | Hackensack | New Jersey | 07601 | Recruiting |
| Northwell Health Physician Partners Center for Advanced IBD Care ( Site 5017) | Great Neck | New York | 11021 | Recruiting |
| Circuit Clinical /Crystal Run Healthcare LLP ( Site 5050) | Middletown | New York | 12589 | Active, not recruiting |
| NYU Langone Health - Inflammatory Bowel Disease Center (IBD) ( Site 5078) | New York | New York | 10016 | Recruiting |
| Weill Cornell Medical College, New-York Presbyterian Hospital ( Site 5079) | New York | New York | 10065 | Recruiting |
| New York Gastroenterology Associates ( Site 5013) | New York | New York | 10075 | Recruiting |
| Northwell Mather Hospital ( Site 5138) | Port Jefferson | New York | 11777 | Recruiting |
| University of North Carolina Medical Center ( Site 5034) | Chapel Hill | North Carolina | 27514 | Recruiting |
| Atrium Health Gastroenterology MMP ( Site 5105) | Charlotte | North Carolina | 28204 | Recruiting |
| Javara - Tryon Medical Partners ( Site 5046) | Charlotte | North Carolina | 28210 | Completed |
| Great Lakes Gastroenterology Research, LLC ( Site 5016) | Mentor | Ohio | 44060 | Recruiting |
| Digestive Disease Specialists Inc. ( Site 5117) | Oklahoma City | Oklahoma | 73114 | Recruiting |
| Penn State University Milton S. Hershey Medical Center ( Site 5102) | Hershey | Pennsylvania | 17033 | Recruiting |
| Thomas Jefferson University Hospital ( Site 5133) | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Frontier Clinical Research, LLC ( Site 5098) | Uniontown | Pennsylvania | 15401 | Recruiting |
| University Gastroenterology - Providence - West River Street ( Site 5057) | Providence | Rhode Island | 02904 | Recruiting |
| Sanford USD Medical Center ( Site 5129) | Sioux Falls | South Dakota | 57105 | Recruiting |
| Vanderbilt Inflammatory Bowel Disease Clinic ( Site 5049) | Nashville | Tennessee | 37204 | Recruiting |
| Quality Medical Research ( Site 5114) | Nashville | Tennessee | 37211 | Recruiting |
| Baylor University Medical Center ( Site 5031) | Dallas | Texas | 75246 | Recruiting |
| GI Alliance - Dallas - Gaston Avenue ( Site 5054) | Dallas | Texas | 75246 | Completed |
| Epic Medical Research - Mesquite ( Site 5153) | Denton | Texas | 76201 | Recruiting |
| Baylor College of Medicine Medical Center ( Site 5020) | Houston | Texas | 77030 | Recruiting |
| Michael E. DeBakey VA Medical Center ( Site 5086) | Houston | Texas | 77030 | Recruiting |
| GI Alliance - Lubbock ( Site 5012) | Lubbock | Texas | 79410 | Recruiting |
| Caprock Gastro Research ( Site 5077) | Lubbock | Texas | 79424 | Recruiting |
| GI Alliance: Mansfield ( Site 5015) | Mansfield | Texas | 76063 | Recruiting |
| Southern Star Research Institute ( Site 5000) | San Antonio | Texas | 78229 | Recruiting |
| GI Alliance - Southlake ( Site 5109) | Southlake | Texas | 76092-9167 | Recruiting |
| Tyler Research Institute ( Site 5001) | Tyler | Texas | 75701 | Recruiting |
| Richmond VA Medical Center ( Site 5021) | Richmond | Virginia | 23249 | Recruiting |
| Washington Gastroenterology - Bellevue ( Site 5040) | Bellevue | Washington | 98004 | Recruiting |
| Swedish Medical Center ( Site 5112) | Seattle | Washington | 98104 | Completed |
| University of Washington ( Site 5115) | Seattle | Washington | 98195 | Recruiting |
| Washington Gastroenterology - Tacoma ( Site 5004) | Tacoma | Washington | 98405 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 412 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06430801, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 3, 2026 · Synced May 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06430801 live on ClinicalTrials.gov.