A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)
Public ClinicalTrials.gov record NCT06439277. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of Tirzepatide Once Weekly Versus Placebo for the Treatment of Obesity and Weight-Related Comorbidities in Adolescents: A Randomized, Double-Blind, Placebo- Controlled Trial (SURMOUNT-ADOLESCENTS-2)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of the study is to assess how tirzepatide impacts bodyweight and cardiovascular risk factors when used in conjunction with healthy nutrition and physical activity in adolescents with obesity and multiple weight related comorbidities. The study will last approximately 76 weeks and may include up to 23 visits. Participants who have completed the primary 72-week GPIX study and have been off treatment for no more than 12 weeks (including the 4-week safety follow-up period), will have the opportunity to receive an additional 156 weeks of treatment with tirzepatide as well as continuing the lifestyle intervention.
Study identification
- NCT ID
- NCT06439277
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 300 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2, 2024
- Primary completion
- Sep 30, 2027
- Completion
- Nov 30, 2030
- Last update posted
- Sep 3, 2026
2024 – 2030
United States locations
- U.S. sites
- 14
- U.S. states
- 8
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Children's Hospital Los Angeles | Los Angeles | California | 90027 | Active, not recruiting |
| Sutter Valley Medical Foundation (SVMF) Pediatric Endocrinology | Sacramento | California | 95821 | Active, not recruiting |
| Nemours Children's Health - Delaware | Wilmington | Delaware | 19803 | Active, not recruiting |
| Medical Research Partners | Ammon | Idaho | 83406 | Active, not recruiting |
| Ann & Robert H. Lurie Children's Hospital of Chicago | Chicago | Illinois | 60611 | Active, not recruiting |
| Indiana University Health University Hospital | Indianapolis | Indiana | 46202 | Active, not recruiting |
| UBMD Pediatrics | Buffalo | New York | 14203 | Active, not recruiting |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | Active, not recruiting |
| Driscoll Children's Hospital | Corpus Christi | Texas | 78411 | Active, not recruiting |
| Epic Medical Research - DeSoto | DeSoto | Texas | 75115 | Active, not recruiting |
| Valley Institute of Research - Fort Worth | Fort Worth | Texas | 76164 | Active, not recruiting |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | Active, not recruiting |
| Texas Valley Clinical Research | Weslaco | Texas | 78596 | Active, not recruiting |
| Alliance for Multispecialty Research, LLC | Layton | Utah | 84041 | Completed |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 55 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06439277, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 3, 2026 · Synced Sep 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06439277 live on ClinicalTrials.gov.