Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
Public ClinicalTrials.gov record NCT06445062. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Platform Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
Study identification
- NCT ID
- NCT06445062
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Revolution Medicines, Inc.
- Industry
- Enrollment
- 1,130 participants
Conditions and interventions
Conditions
Interventions
- RMC-6236 Drug
- RMC-9805 Drug
- bevacizumab Drug
- cetuximab Drug
- gemcitabine Drug
- mFOLFIRINOX regimen Drug
- mFOLFOX6 regimen Drug
- nab-paclitaxel Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 23, 2024
- Primary completion
- May 14, 2027
- Completion
- Jul 14, 2027
- Last update posted
- Mar 31, 2026
2024 – 2027
United States locations
- U.S. sites
- 32
- U.S. states
- 21
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Ironwood Cancer and Research Centers | Chandler | Arizona | 85224 | Recruiting |
| Mayo Clinic Hospital | Phoenix | Arizona | 85054 | Recruiting |
| HonorHealth Research Institute | Scottsdale | Arizona | 85258 | Recruiting |
| UC San Diego Moores Cancer Center | La Jolla | California | 92093 | Recruiting |
| Cedars-Sinai Cancer at Cedars-Sinai Medical Center | Los Angeles | California | 90048 | Recruiting |
| UCLA Hematology/Oncology- Santa Monica | Los Angeles | California | 90404 | Recruiting |
| University of Colorado Hospital-Anschutz Cancer Pavilion | Aurora | Colorado | 88045 | Recruiting |
| Yale-New Haven Hospital-Yale Cancer Center | New Haven | Connecticut | 06520 | Recruiting |
| Mayo Clinic Cancer Center | Jacksonville | Florida | 32224 | Recruiting |
| Moffitt Cancer Center | Tampa | Florida | 33612 | Recruiting |
| The University of Kansas Clinical Research Center | Westwood | Kansas | 66205 | Recruiting |
| The Sidney Kimmel Comprehensive Cancer Center at John Hopkins | Baltimore | Maryland | 21287 | Recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Recruiting |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | Recruiting |
| Mayo Clinic | Rochester | Minnesota | 55905 | Recruiting |
| Nebraska Cancer Specialists | Omaha | Nebraska | 68130 | Recruiting |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | Recruiting |
| Atlantic Health System | Morristown | New Jersey | 07960 | Recruiting |
| Northwell Health / RJ Zuckerberg Cancer Center | Lake Success | New York | 11042 | Recruiting |
| Columbia University Medical Center | New York | New York | 10032 | Recruiting |
| Memorial Sloan Kettering Cancer Center Main Campus | New York | New York | 10065 | Recruiting |
| Duke University Medical Center | Durham | North Carolina | 27710 | Recruiting |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45267 | Recruiting |
| Stephenson Cancer Center | Oklahoma City | Oklahoma | 73104 | Recruiting |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | Recruiting |
| SCRI Oncology Partners | Nashville | Tennessee | 37203 | Recruiting |
| Baylor College of Medicine | Houston | Texas | 77030 | Recruiting |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| NEXT Oncology Dallas | Irving | Texas | 75039 | Recruiting |
| Huntsman Cancer Institute, University of Utah | Salt Lake City | Utah | 84112 | Recruiting |
| Virginia Cancer Specialists | Fairfax | Virginia | 22314 | Recruiting |
| Fred Hutchinson Cancer Center | Seattle | Washington | 98109 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06445062, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 31, 2026 · Synced May 10, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06445062 live on ClinicalTrials.gov.