A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG)
Public ClinicalTrials.gov record NCT06456580. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study With an Open-label Extension Period to Evaluate the Efficacy and Safety of Telitacicept in Patients With Generalized Myasthenia Gravis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of telitacicept in the treatment of generalized myasthenia gravis.
Study identification
- NCT ID
- NCT06456580
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 191 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 17, 2024 (Actual)
- Primary completion
- Mar 2027 (Estimated)
- Completion
- Jan 2029 (Estimated)
- Last update posted
- Oct 15, 2026
2024 – 2029
United States locations
- U.S. sites
- 30
- U.S. states
- 18
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| HonorHealth Neurology - Bob Bové Neuroscience Institute | Scottsdale | Arizona | 85258 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| University of California Irvine | Orange | California | 92868 | — |
| University of California San Francisco (UCSF) | San Francisco | California | 94143 | — |
| SFM Clinical Research | Boca Raton | Florida | 33487 | — |
| BayCare Medical Group - Clearwater | Clearwater | Florida | 33759 | — |
| Allied Biomedical Research Institute (ABRI) | Miami | Florida | 33155 | — |
| Medsol Clinical Research Center | Port Charlotte | Florida | 33952 | — |
| University of South Florida Health (USF Health) | Tampa | Florida | 33613 | — |
| Wellstar MCG Health Medical Center | Augusta | Georgia | 30912 | — |
| Hospital Sisters Health System Medical | O'Fallon | Illinois | 62269 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Kentucky | Lexington | Kentucky | 40506 | — |
| University of Louisville Physicians | Louisville | Kentucky | 40202 | — |
| Neurology Center of New England | Foxborough | Massachusetts | 02035 | — |
| Michigan State University Clinical Center | East Lansing | Michigan | 48824 | — |
| Trinity Health - Grand Rapids Hospital | Grand Rapids | Michigan | 49503 | — |
| UM Health Care - Neurology and Sleep Disorders Clinic | Columbia | Missouri | 65212 | — |
| Robert Wood Johnson University Hospital New Brunswick | New Brunswick | New Jersey | 08901 | — |
| Lange Neurology | New York | New York | 10022 | — |
| Mount Sinai Health System | New York | New York | 10029 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| University of North Carolina Hospitals - Neurology Clinic | Chapel Hill | North Carolina | 27517 | — |
| University of Cincinnati Health Physicians - Clifton | Cincinnati | Ohio | 45219 | — |
| Empower Clinical Research | Tigard | Oregon | 97223 | — |
| University of Tennessee Medical Center | Knoxville | Tennessee | 37920 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Neurology Rare Disease Center | Flower Mound | Texas | 75028 | — |
| Houston Methodist Neurological Institute | Houston | Texas | 77030 | — |
| Center for Neurological Disorders, S.C. - Greenfield - Gamma Therapeutic Center | Greenfield | Wisconsin | 53228 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 90 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06456580, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 15, 2026 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06456580 live on ClinicalTrials.gov.