A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG)
Public ClinicalTrials.gov record NCT06456580. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study With an Open-label Extension Period to Evaluate the Efficacy and Safety of Telitacicept in Patients With Generalized Myasthenia Gravis
Study identification
- NCT ID
- NCT06456580
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Vor Biopharma
- Industry
- Enrollment
- 180 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- Telitacicept Biological
Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 16, 2024
- Primary completion
- Apr 30, 2027
- Completion
- Dec 31, 2028
- Last update posted
- May 6, 2026
2024 – 2029
United States locations
- U.S. sites
- 20
- U.S. states
- 11
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Southern California | Los Angeles | California | 90033 | Recruiting |
| University of California Irvine | Orange | California | 92868 | Recruiting |
| University of California San Francisco (UCSF) | San Francisco | California | 94143 | Recruiting |
| SFM Clinical Research | Boca Raton | Florida | 33487 | Recruiting |
| Allied Biomedical Research Institute (ABRI) | Miami | Florida | 33155 | Recruiting |
| Medsol Clinical Research Center | Port Charlotte | Florida | 33952 | Recruiting |
| University of South Florida Health (USF Health) | Tampa | Florida | 33613 | Recruiting |
| Wellstar MCG Health Medical Center | Augusta | Georgia | 30912 | Recruiting |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | Recruiting |
| University of Kentucky | Lexington | Kentucky | 40506 | Recruiting |
| University of Louisville Physicians | Louisville | Kentucky | 40202 | Recruiting |
| Neurology Center of New England | Foxborough | Massachusetts | 02035 | Recruiting |
| Michigan State University Clinical Center | East Lansing | Michigan | 48824 | Recruiting |
| Trinity Health - Grand Rapids Hospital | Grand Rapids | Michigan | 49503 | Recruiting |
| Mount Sinai Health System | New York | New York | 10029 | Recruiting |
| Montefiore Medical Center | The Bronx | New York | 10467 | Recruiting |
| University of Cincinnati Health Physicians - Clifton | Cincinnati | Ohio | 45219 | Recruiting |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | Recruiting |
| Houston Methodist Neurological Institute | Houston | Texas | 77030 | Recruiting |
| Center for Neurological Disorders, S.C. - Greenfield - Gamma Therapeutic Center | Greenfield | Wisconsin | 53228 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 85 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06456580, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 6, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06456580 live on ClinicalTrials.gov.