A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis
Public ClinicalTrials.gov record NCT06461897. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Open-label, Efficacy-Assessor-Blinded Study, Comparing the Safety and Efficacy of Upadacitinib to Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis
Study identification
- NCT ID
- NCT06461897
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- AbbVie
- Industry
- Enrollment
- 675 participants
Conditions and interventions
Conditions
Interventions
- Dupilumab Drug
- Upadacitinib Drug
Drug
Eligibility (public fields only)
- Age range
- 2 Years to 11 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 18, 2024
- Primary completion
- Jun 30, 2030
- Completion
- Jun 30, 2030
- Last update posted
- Apr 6, 2026
2024 – 2030
United States locations
- U.S. sites
- 30
- U.S. states
- 19
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Applied Research Center Of Arkansas /ID# 268547 | Little Rock | Arkansas | 72205 | Recruiting |
| Stanford University School of Medicine - Palo Alto /ID# 269622 | Palo Alto | California | 94304 | Recruiting |
| Integrative Skin Science and Research /ID# 265108 | Sacramento | California | 95815 | Recruiting |
| Clearlyderm Dermatology - West Boca /ID# 266323 | Boca Raton | Florida | 33428 | Completed |
| Pediatric Skin Research /ID# 266308 | Coral Gables | Florida | 33146 | Recruiting |
| Neoclinical Research - Hialeah /ID# 269694 | Hialeah | Florida | 33016 | Completed |
| Cleaver Medical Group Dermatology /ID# 265099 | Dawsonville | Georgia | 30534 | Completed |
| Aeroallergy Research Laboratory /ID# 267247 | Savannah | Georgia | 31406 | Recruiting |
| Treasure Valley Medical Research /ID# 266838 | Boise | Idaho | 83706 | Recruiting |
| Northwestern University Feinberg School of Medicine /ID# 265117 | Chicago | Illinois | 60611-2927 | Recruiting |
| Sneeze Wheeze & Itch Associates /ID# 267238 | Normal | Illinois | 61761 | Recruiting |
| Dawes Fretzin, LLC /ID# 265097 | Indianapolis | Indiana | 46256 | Recruiting |
| Equity Medical, LLC /ID# 268270 | Bowling Green | Kentucky | 42104 | Recruiting |
| Maryland Allergy & Asthma Center /ID# 268032 | Lanham | Maryland | 20706 | Recruiting |
| DermAssociates - Rockville /ID# 266457 | Rockville | Maryland | 20850 | Recruiting |
| Washington University School of Medicine - St. Louis /ID# 268545 | St Louis | Missouri | 63130 | Recruiting |
| Skin Specialists /ID# 266331 | Omaha | Nebraska | 68144 | Recruiting |
| DOCS Clinical Research - Canal Winchester /ID# 268271 | Canal Winchester | Ohio | 43110-2069 | Recruiting |
| Wright State Physicians Health Center /ID# 268841 | Fairborn | Ohio | 45324 | Recruiting |
| Oregon Health and Science University /ID# 266483 | Portland | Oregon | 97239 | Recruiting |
| Medical University of South Carolina /ID# 265113 | Charleston | South Carolina | 29425 | Recruiting |
| International Clinical Research - Tennessee /ID# 268548 | Murfreesboro | Tennessee | 37130 | Completed |
| Arlington Research Center, Inc /ID# 266330 | Arlington | Texas | 76011 | Recruiting |
| 3A Research - East location /ID# 267622 | El Paso | Texas | 79925 | Recruiting |
| Prime Clinical Research - Mansfield - East Broad Street /ID# 268042 | Mansfield | Texas | 76063 | Recruiting |
| Texas Dermatology and Laser Specialists /ID# 267249 | San Antonio | Texas | 78218 | Recruiting |
| Progressive Clinical Research - San Antonio /ID# 267262 | San Antonio | Texas | 78229 | Recruiting |
| Jordan Valley Dermatology & Research Center /ID# 267092 | South Jordan | Utah | 84095 | Recruiting |
| West Virginia University Hospitals /ID# 265114 | Morgantown | West Virginia | 26506 | Recruiting |
| Wisconsin Medical Center /ID# 267236 | Milwaukee | Wisconsin | 53226 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 118 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06461897, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 6, 2026 · Synced May 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06461897 live on ClinicalTrials.gov.