ClinicalTrials.gov record
Recruiting Phase 3 Interventional

Study of Lumateperone in the Acute Treatment of Patients With Bipolar Mania

ClinicalTrials.gov ID: NCT06462586

Public ClinicalTrials.gov record NCT06462586. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 29, 2026, 9:42 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy and Safety of Lumateperone in the Acute Treatment of Patients With Manic Episodes or Manic Episodes With Mixed Features Associated With Bipolar I Disorder (Bipolar Mania)

Study identification

NCT ID
NCT06462586
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Intra-Cellular Therapies, Inc.
Industry
Enrollment
350 participants

Conditions and interventions

Interventions

  • Lumateperone Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 18, 2024
Primary completion
Feb 28, 2026
Completion
Mar 31, 2026
Last update posted
Jun 30, 2025

2024 – 2026

United States locations

U.S. sites
23
U.S. states
8
U.S. cities
21
Facility City State ZIP Site status
Clinical Site Rogers Arkansas 72758 Recruiting
Clinical Site Bellflower California 90706 Not yet recruiting
Clinical Site Culver City California 90230 Recruiting
Clinical Site Garden Grove California 92845 Recruiting
Clinical Site Lemon Grove California 91945 Recruiting
Clinical Site Montclair California 91763 Recruiting
Clinical Site Hallandale Florida 33009 Recruiting
Clinical Site Hialeah Florida 33016 Recruiting
Clinical Site Miami Florida 33184 Not yet recruiting
Clinical Site Miami Gardens Florida 33056 Not yet recruiting
Clinical Site Miami Lakes Florida 33016 Recruiting
Clinical Site Miami Springs Florida 33166 Recruiting
Clinical Site Orlando Florida 32807 Recruiting
Clinical Site Atlanta Georgia 30324 Recruiting
Clinical Site Atlanta Georgia 30338 Not yet recruiting
Clinical Site Decatur Georgia 30030 Recruiting
Clinical Site Savannah Georgia 31405 Recruiting
Clinical Site Shreveport Louisiana 71101 Recruiting
Clinical Site Marlton New Jersey 08053 Recruiting
Clinical Site North Canton Ohio 44720 Recruiting
Clinical Site Austin Texas 78701 Not yet recruiting
Clinical Site Austin Texas 78754 Recruiting
Clinical Site DeSoto Texas 75115 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06462586, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 30, 2025 · Synced Apr 29, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06462586 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →