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Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

ClinicalTrials.gov ID: NCT06465810

Public ClinicalTrials.gov record NCT06465810. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 4, 2026, 8:42 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Non-interventional, Prospective, Multi-country Study Collecting Real-world Data on the Characteristics, Treatment Patterns, and Outcomes of Patients With Transthyretin (ATTR) Amyloidosis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The MaesTTRo study aims to enroll a global cohort of patients with transthyretin (ATTR) amyloidosis to longitudinally observe the natural course of the disease and describe real-world treatment patterns and outcomes. In addition, information on the effectiveness of ATTR amyloidosis treatments, including eplontersen, which is a ligand-conjugated antisense oligonucleotide gene silencing treatment targeting activity against both the mutant and wild-type TTR protein, will be collected.

Study identification

NCT ID
NCT06465810
Recruitment status
Recruiting
Study type
Observational
Phase
Not listed
Lead sponsor
AstraZeneca
Industry
Enrollment
1,850 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 130 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 24, 2024
Primary completion
Dec 28, 2031
Completion
Dec 28, 2031
Last update posted
Aug 18, 2026

2024 – 2031

United States locations

U.S. sites
33
U.S. states
20
U.S. cities
27
Facility City State ZIP Site status
Research Site La Jolla California 92037 Recruiting
Research Site Los Angeles California 90095 Recruiting
Research Site San Francisco California 94025 Recruiting
Research Site San Francisco California 94143 Recruiting
Research Site New Haven Connecticut 006510 Recruiting
Research Site Washington D.C. District of Columbia 20010 Recruiting
Research Site Chicago Illinois 60637 Recruiting
Research Site Indianapolis Indiana 06200 Recruiting
Research Site Baltimore Maryland 21218 Recruiting
Research Site Boston Massachusetts 02111 Recruiting
Research Site Boston Massachusetts 02114 Not yet recruiting
Research Site Boston Massachusetts 02115 Recruiting
Research Site Rochester Minnesota 55905 Recruiting
Research Site Kansas City Missouri 64111 Recruiting
Research Site St Louis Missouri 63110 Recruiting
Research Site New Brunswick New Jersey 08901 Recruiting
Research Site Manhasset New York 11030 Recruiting
Research Site New York New York 10016 Not yet recruiting
Research Site New York New York 10027 Recruiting
Research Site New York New York 10029 Recruiting
Research Site Durham North Carolina 27710 Recruiting
Research Site Portland Oregon 97239 Recruiting
Research Site Danville Pennsylvania 17822 Recruiting
Research Site Philadelphia Pennsylvania 19104 Recruiting
Research Site Philadelphia Pennsylvania 19107 Recruiting
Research Site Greenville South Carolina 29607 Recruiting
Research Site Germantown Tennessee 38138 Recruiting
Research Site Nashville Tennessee 037214 Recruiting
Research Site Dallas Texas 75246 Recruiting
Research Site Houston Texas 77030 Not yet recruiting
Research Site Richmond Virginia 23298 Recruiting
Research Site Seattle Washington 98915 Recruiting
Research Site Milwaukee Wisconsin 53226 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 56 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06465810, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 18, 2026 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06465810 live on ClinicalTrials.gov.

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