A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy
Public ClinicalTrials.gov record NCT06481891. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of SOtaglifloziN in symptomATic Obstructive And Non-obstructive Hypertrophic CardioMyopathy (SONATA-HCM)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of the study is to determine the changes in symptoms and functional limitations in participants with symptomatic hypertrophic cardiomyopathy (HCM) treated with sotagliflozin as compared to placebo.
Study identification
- NCT ID
- NCT06481891
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 500 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 24, 2024 (Actual)
- Primary completion
- Jan 2027 (Estimated)
- Completion
- Feb 2027 (Estimated)
- Last update posted
- Aug 26, 2026
2024 – 2027
United States locations
- U.S. sites
- 33
- U.S. states
- 23
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Lexicon Investigational Site (4041) | Phoenix | Arizona | 85054 | — |
| Lexicon Investigational Site (4037) | Scottsdale | Arizona | 85260 | — |
| Lexicon Investigational Site (4012) | Los Angeles | California | 90048 | — |
| Lexicon Investigational Site (4035) | Pomona | California | 91767 | — |
| Lexicon Investigational Site (4044) | San Francisco | California | 94143 | — |
| Lexicon Investigational Site (4046) | Jacksonville | Florida | 32224 | — |
| Lexicon Investigational Site (4034) | Orlando | Florida | 32804 | — |
| Lexicon Investigational Site (4018) | Atlanta | Georgia | 30322 | — |
| Lexicon Investigational Site (4033) | Evanston | Illinois | 60208 | — |
| Lexicon Investigational Site (4036) | Merrillville | Indiana | 46410 | — |
| Lexicon Investigational Site (4021) | Baltimore | Maryland | 21218 | — |
| Lexicon Investigational Site (4016) | Boston | Massachusetts | 02115 | — |
| Lexicon Investigational Site (4042) | Boston | Massachusetts | 02118 | — |
| Lexicon Investigational Site (4028) | Ann Arbor | Michigan | 48109 | — |
| Lexicon Investigational Site (4038) | Grand Rapids | Michigan | 49525 | — |
| Lexicon Investigational Site (4027) | Rochester | Minnesota | 55905 | — |
| Lexicon Investigational Site (4013) | St Louis | Missouri | 63110 | — |
| Lexicon Investigational Site (4029) | Morristown | New Jersey | 07960 | — |
| Lexicon Investigational Site (4039) | Manhasset | New York | 11030 | — |
| Lexicon Investigational Site (4043) | New York | New York | 10016 | — |
| Lexicon Investigational Site (4026) | Morrisville | North Carolina | 27560 | — |
| Lexicon Investigational Site (4031) | Cincinnati | Ohio | 45219 | — |
| Lexicon Investigational Site (4017) | Cleveland | Ohio | 44195 | — |
| Lexicon Investigational Site (4024) | Tulsa | Oklahoma | 74104 | — |
| Lexicon Investigational Site (4015) | Portland | Oregon | 97239 | — |
| Lexicon Investigational Site (4011) | Philadelphia | Pennsylvania | 19104 | — |
| Lexicon Investigational Site (4019) | Germantown | Tennessee | 38138 | — |
| Lexicon Investigational Stie (4014) | Houston | Texas | 77030 | — |
| Lexicon Investigational Site (4032) | Charlottesville | Virginia | 22908 | — |
| Lexicon Investigational Site (4045) | Seattle | Washington | 98101 | — |
| Lexicon Investigational Site (4010) | Seattle | Washington | 98195 | — |
| Lexicon Investigational Site (4022) | Marshfield | Wisconsin | 54449 | — |
| Lexicon Investigational Site (4040) | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 75 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06481891, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 26, 2026 · Synced Oct 28, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06481891 live on ClinicalTrials.gov.