Evaluation of the Safety and Efficacy of Revita® DMR on Body Weight Maintenance in Subjects With Obesity Who Have Achieved at Least 15% Weight Loss on Tirzepatide
Public ClinicalTrials.gov record NCT06484114. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective, Randomized, Double-Blind, Sham-Controlled, Multicenter, Pivotal Study to Assess the Efficacy of Revita® Duodenal Mucosal Resurfacing (DMR) on Body Weight Maintenance in Participants With Obesity and Who Have Achieved at Least 15% Weight Loss on Tirzepatide Obesity Pharmacotherapy
Study identification
- NCT ID
- NCT06484114
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Lead sponsor
- Fractyl Health Inc.
- Industry
- Enrollment
- 315 participants
Conditions and interventions
Conditions
Interventions
- Revita Duodenal Mucosal Resurfacing (DMR) Device
- Sham Device
Device
Eligibility (public fields only)
- Age range
- 21 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2024
- Primary completion
- Feb 14, 2027
- Completion
- Feb 25, 2027
- Last update posted
- Mar 2, 2026
2024 – 2027
United States locations
- U.S. sites
- 32
- U.S. states
- 11
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Helios Clinical Research | Phoenix | Arizona | 85028 | — |
| Honor Health | Scottsdale | Arizona | 85258 | — |
| Hoag Hospital | Newport Beach | California | 92663 | — |
| UCLA Santa Monica Medical Center | Santa Monica | California | 90095 | — |
| Zenith Clinical Research | Hollywood | Florida | 33021 | — |
| Nature Coast Clinical Research | Inverness | Florida | 32162 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Encore Borland-Groover Clinical Research | Jacksonville | Florida | 32256 | — |
| International Research Associates | Miami | Florida | 33183 | — |
| Advent Health | Orlando | Florida | 32804 | — |
| K2 Medical Research South Orlando | Orlando | Florida | 32806 | — |
| Orlando Health Weight Loss and Bariatric Surgery Institute | Orlando | Florida | 32806 | — |
| Synexus Clinical Research Institute - The Villages (AES) | The Villages | Florida | 32162 | — |
| Metabolic Research Institute | West Palm Beach | Florida | 33401 | — |
| Cleveland Clinic, Weston | Weston | Florida | 33331 | — |
| Investigators Research Group, LLC | Brownsburg | Indiana | 46112 | — |
| American Health Network - Franklin | Franklin | Indiana | 46131 | — |
| American Health Network - Greenfield | Greenfield | Indiana | 46140 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| American Health Network - Muncie | Muncie | Indiana | 47304 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| NYC Research, Inc. (Endocrine Associates of West Village) | Long Island City | New York | 11106 | — |
| NYU-Langone | New York | New York | 10016 | — |
| Preferred Primary Care Physician Pittsburgh | Pittsburgh | Pennsylvania | 15243 | — |
| Preferred Primary Care Physician | Pittsburgh | Pennsylvania | 15326 | — |
| Preferred Primary Care Physician | Uniontown | Pennsylvania | 15401 | — |
| Baylor St. Luke's Medical Center | Houston | Texas | 77030 | — |
| Juno Research, LLC | Houston | Texas | 77040 | — |
| Simcare Medical Research LLC | Sugar Land | Texas | 77478 | — |
| University of Washington, Seattle | Seattle | Washington | 98109 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06484114, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 2, 2026 · Synced May 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06484114 live on ClinicalTrials.gov.