Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

ClinicalTrials.gov ID: NCT06500273

Public ClinicalTrials.gov record NCT06500273. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 8:09 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Open-label Study Evaluating the Efficacy and Safety of Cemacabtagene Ansegedleucel in Participants With Minimal Residual Disease After Response to First Line Therapy for Large B-cell Lymphoma

Study identification

NCT ID: NCT06500273
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Allogene Therapeutics; Industry
Enrollment: 250 participants

Conditions and interventions

Conditions

Large B-cell Lymphoma

Interventions

Cyclophosphamide Drug
Fludarabine Drug
Foresight CLARITY™ IUO MRD test, powered by PhasED-Seq™ Device
cemacabtagene ansegedleucel Genetic

Drug · Device · Genetic

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jun 17, 2024
Primary completion: Nov 30, 2027
Completion: Nov 30, 2032
Last update posted: May 5, 2026

2024 – 2032

United States locations

U.S. sites: 58
U.S. states: 27
U.S. cities: 50

Facility	City	State	ZIP	Site status
Banner MD Anderson Cancer Center	Gilbert	Arizona	85234	Recruiting
Genesis Cancer and Blood Institute	Hot Springs	Arkansas	71913	Recruiting
Alta Bates Summit Medical Center	Berkeley	California	94704	Recruiting
City of Hope	Duarte	California	91010	Recruiting
Cedars-Sinai Medical Center	Los Angeles	California	90048	Recruiting
University of California, Los Angeles	Los Angeles	California	90095	Recruiting
University of California, Davis Comprehensive Cancer Center	Sacramento	California	91817	Recruiting
University of California, San Diego	San Diego	California	92037	Recruiting
University of California, San Francisco	San Francisco	California	94143	Recruiting
Rocky Mountain Cancer Centers	Denver	Colorado	80218	Recruiting
Medical Oncology Hematology Consultants	Newark	Delaware	19713	Recruiting
MedStar Georgetown University Hospital	Washington D.C.	District of Columbia	20007	Recruiting
Miami Cancer Institute at Baptist Health, Inc.	Miami	Florida	33176	Recruiting
Advent Health Cancer Institute	Orlando	Florida	32804	Recruiting
Orlando Health Cancer Institute	Orlando	Florida	32806	Recruiting
Moffitt Cancer Center	Tampa	Florida	33612	Recruiting
Augusta University Georgia Cancer Center	Augusta	Georgia	30912	Recruiting
Rush University Medical Center	Chicago	Illinois	60612	Recruiting
IU Simon Comprehensive Cancer Center	Indianapolis	Indiana	46202	Recruiting
Indiana Blood and Marrow Transplantation	Indianapolis	Indiana	46237	Recruiting
The University of Kansas Hospital	Kansas City	Kansas	66205	Active, not recruiting
University of Kentucky Medical Center	Lexington	Kentucky	40536	Recruiting
University of Louisville Health Brown Cancer Center	Louisville	Kentucky	40202	Recruiting
Norton Cancer Institute	Louisville	Kentucky	40207	Recruiting
University of Maryland Greenebaum Comprehensive Cancer Center	Baltimore	Maryland	21201	Recruiting
The Center for Cancer and Blood Disorders	Bethesda	Maryland	20817	Recruiting
Massachusetts General Hospital	Boston	Massachusetts	02114	Recruiting
Beth Israel Deaconess Medical Center	Boston	Massachusetts	02215	Recruiting
University of Missouri - Ellis Fischel Cancer Center	Columbia	Missouri	65212	Recruiting
MidAmerica Cancer Care	Kansas City	Missouri	64132	Recruiting
Washington University School of Medicine - Siteman Cancer Center	St Louis	Missouri	63110	Recruiting
Astera Cancer Care	East Brunswick	New Jersey	08816	Recruiting
John Theurer Cancer Center	Hackensack	New Jersey	07601	Recruiting
Rutgers Cancer Institute of New Jersey	New Brunswick	New Jersey	08901	Recruiting
Columbia University Irving Medical Center and New York-Presbyterian Hospital	New York	New York	10032	Recruiting
University of Rochester Medical Center	Rochester	New York	14642	Recruiting
Novant Health Cancer Institute- Hematology	Charlotte	North Carolina	28204	Recruiting
Duke Blood Cancer Center	Durham	North Carolina	27705	Recruiting
Oncology Hematology Care - Kenwood	Cincinnati	Ohio	45236	Recruiting
University of Cincinnati Medical Center	Cincinnati	Ohio	45267	Recruiting
Cleveland Clinic	Cleveland	Ohio	44195	Recruiting
Oncology Associates of Oregon	Eugene	Oregon	97401	Recruiting
Oregon Health and Science University	Portland	Oregon	97239	Recruiting
Fox Chase Cancer Center	Philadelphia	Pennsylvania	19111	Recruiting
Avera Cancer Institute	Sioux Falls	South Dakota	57105	Recruiting
Vanderbilt University Medical Center	Nashville	Tennessee	37232	Recruiting
Texas Oncology - Central South	Austin	Texas	78705	Recruiting
Texas Oncology - Dallas Fort Worth	Dallas	Texas	75246	Recruiting
MD Anderson Cancer Center	Houston	Texas	77030	Recruiting
Texas Transplant Institute	San Antonio	Texas	78229	Recruiting
Texas Oncology - Tyler	Tyler	Texas	75702	Recruiting
Huntsman Cancer Institute, University of Utah	Salt Lake City	Utah	84112	Recruiting
Intermountain Health LDS Hospital	Salt Lake City	Utah	84142	Recruiting
University of Virginia	Charlottesville	Virginia	22903	Recruiting
Virginia Cancer Specialists	Fairfax	Virginia	22031	Recruiting
Virginia Oncology Associates - Norfolk	Norfolk	Virginia	23502	Recruiting
Swedish Cancer Institute	Seattle	Washington	98104	Recruiting
Fred Hutchinson Cancer Center	Seattle	Washington	98109	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06500273, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 5, 2026 · Synced May 8, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06500273 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →