A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events

ClinicalTrials.gov ID: NCT06500884

Public ClinicalTrials.gov record NCT06500884. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 3:55 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Open-label, Randomized Study to Evaluate GPRC5D-related Oral Events

Study identification

NCT ID: NCT06500884
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Janssen Research & Development, LLC; Industry
Enrollment: 210 participants

Conditions and interventions

Conditions

Multiple Myeloma

Interventions

Prophylaxis A Drug
Prophylaxis B Drug
Prophylaxis C Drug
Prophylaxis D Drug
Ramantamig Drug
Talquetamab Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Aug 25, 2024
Primary completion: Apr 14, 2026
Completion: Apr 29, 2029
Last update posted: Apr 12, 2026

2024 – 2029

United States locations

U.S. sites: 9
U.S. states: 8
U.S. cities: 9

Facility	City	State	ZIP	Site status
University of California San Francisco	San Francisco	California	94143	Recruiting
Colorado Blood Cancer Institute	Denver	Colorado	80218	Recruiting
Yale University School Of Medicine	New Haven	Connecticut	06510	Recruiting
Icahn School of Medicine at Mt. Sinai	New York	New York	10029	Recruiting
University of Rochester Medical Center	Rochester	New York	14642	Recruiting
Duke University Medical Center	Durham	North Carolina	27705	Recruiting
University Hospitals Cleveland Medical Center	Cleveland	Ohio	44106	Recruiting
Virginia Commonwealth University - Massey Cancer Center	Richmond	Virginia	23298	Recruiting
University of Washington	Seattle	Washington	98109	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 29 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06500884, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 12, 2026 · Synced May 8, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06500884 live on ClinicalTrials.gov.

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