A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of Vonaprument (Formerly ANX007) in Participants With Dry Age-Related Macular Degeneration (AMD) With Geographic Atrophy (GA)
Public ClinicalTrials.gov record NCT06510816. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Parallel-Group, Double-Masked, 2-Arm, Sham Controlled Study of the Efficacy, Safety, and Tolerability of ANX007 (Vonaprument) Administered by Intravitreal Injection in Participants With Dry Age-Related Macular Degeneration With Geographic Atrophy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary purpose of the study is to determine if IVT injections of vonaprument every month reduce vision loss in participants with dry AMD with GA.
Study identification
- NCT ID
- NCT06510816
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 659 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 30, 2024 (Actual)
- Primary completion
- Jul 31, 2027 (Estimated)
- Completion
- Jul 31, 2027 (Estimated)
- Last update posted
- Oct 6, 2026
2024 – 2027
United States locations
- U.S. sites
- 71
- U.S. states
- 27
- U.S. cities
- 67
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retina Macula Institute of Arizona | Scottsdale | Arizona | 85255 | — |
| Retina-Vitreous Associates Medical Group | Beverly Hills | California | 90211 | — |
| Retinal Consultants of Orange County Clinical Research Institute Inc | Fullerton | California | 92835 | — |
| Global Research Management | Glendale | California | 91204 | — |
| Retina Consultants Medical Group | Modesto | California | 95356 | — |
| Northern California Retina Vitreous Associates Medical Group, Inc. | Mountain View | California | 94040 | — |
| Retinal Consultants Medical Group | Sacramento | California | 95825 | — |
| Macula Retina Vitreous Research Institute | Torrance | California | 90503 | — |
| Bay Area Retina Associates | Walnut Creek | California | 94598 | — |
| Retina Consultants of Southern Colorado PC | Colorado Springs | Colorado | 80909 | — |
| RSC Research, LLC | Denver | Colorado | 80222 | — |
| Rand Eye Institute | Deerfield Beach | Florida | 33064 | — |
| National Ophthalmic Research Institute | Fort Myers | Florida | 33912 | — |
| Florida Retina Institute | Orlando | Florida | 32806 | — |
| Fort Lauderdale Eye Institute | Plantation | Florida | 33324 | — |
| Retina Group of Florida | Sarasota | Florida | 34232 | — |
| Retina Vitreous Associates of Florida | St. Petersburg | Florida | 33711 | — |
| East Florida Eye Institute | Stuart | Florida | 34994 | — |
| Retina Associates of Florida | Tampa | Florida | 33609 | — |
| Georgia Retina PC | Marietta | Georgia | 30060 | — |
| Retina Consultants of Hawaii | ‘Aiea | Hawaii | 96701 | — |
| Retina Associates Ltd | Elmhurst | Illinois | 60126 | — |
| University Retina | Oak Forest | Illinois | 60452 | — |
| Springfield Clinic LLP | Springfield | Illinois | 62703 | — |
| Wolfe Eye Clinic | West Des Moines | Iowa | 50266 | — |
| Maine Eye Center | Portland | Maine | 04101 | — |
| Retina Group of Washington | Chevy Chase | Maryland | 20815 | — |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | — |
| Mid Atlantic Retina Specialists | Hagerstown | Maryland | 21740 | — |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02114 | — |
| Retina Research Institute at New England Retina Consultants | Springfield | Massachusetts | 01107 | — |
| Retina Consultants of Minnesota | Saint Louis Park | Minnesota | 55416 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| Envision Ocular, LLC | Bloomfield | New Jersey | 07003 | — |
| Mid Atlantic Retina New Jersey | Cherry Hill | New Jersey | 08054 | — |
| Vision Research Center Eye Associates of New Mexico | Albuquerque | New Mexico | 87109 | — |
| Long Island Vitreoretinal Consultants | Hauppauge | New York | 11788 | — |
| Asheville Eye Associates - Retina Division | Asheville | North Carolina | 28803 | — |
| North Carolina Retina Associates | Cary | North Carolina | 27511 | — |
| North Carolina Retina Associates | Wake Forest | North Carolina | 27587 | — |
| Piedmont Retina Specialists | Winston-Salem | North Carolina | 27103 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Retina Vitreous Center | Edmond | Oklahoma | 73013 | — |
| Tulsa Retina Consultants | Tulsa | Oklahoma | 74114 | — |
| Verum Research, LLC | Eugene | Oregon | 97401 | — |
| Eyehealth Northwest Portland | Portland | Oregon | 97209 | — |
| Cascade Medical Research Institute | Springfield | Oregon | 97477 | — |
| Erie Retina Research, LLC | Erie | Pennsylvania | 16507 | — |
| Eye Care Specialists | Kingston | Pennsylvania | 18704 | — |
| Palmetto Retina Center | Aiken | South Carolina | 29802 | — |
| Retina Consultants of Charleston | Beaufort | South Carolina | 29901 | — |
| Charleston Neuroscience Center | Charleston | South Carolina | 29414 | — |
| Southeastern Retina Associates | Johnson City | Tennessee | 37604 | — |
| Retina Research Institute of Texas | Abilene | Texas | 79606 | — |
| Southwest Retina Specialists | Amarillo | Texas | 79106 | — |
| Texas Retina Associates- Arlington | Arlington | Texas | 76012 | — |
| Austin Research Center for Retina | Austin | Texas | 78705 | — |
| Austin Retina Associates | Austin | Texas | 78705 | — |
| Austin Clinical Research, LLC | Austin | Texas | 78750 | — |
| Retina Consultants of Texas | Bellaire | Texas | 77401 | — |
| Retina Foundation of the Southwest | Dallas | Texas | 75231 | — |
| Texas Retina Associates | Dallas | Texas | 75231 | — |
| Texas Retina Associates | Fort Worth | Texas | 76104 | — |
| Retina Consultants of Texas | Katy | Texas | 77494 | — |
| Tennessee Retina PC | Nashville | Texas | 37203 | — |
| Retina Consultants of Texas San Antonio | San Antonio | Texas | 78240 | — |
| Retina Consultants of Texas | The Woodlands | Texas | 77384 | — |
| Strategic Clinical Research Group, LLC | Willow Park | Texas | 76087 | — |
| Rocky Mountain Retina Consultants | Salt Lake City | Utah | 84107 | — |
| Piedmont Eye Center | Lynchburg | Virginia | 24502 | — |
| Eye Clinic of Wisconsin | Wausau | Wisconsin | 54403 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 61 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06510816, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 6, 2026 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06510816 live on ClinicalTrials.gov.