A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

ClinicalTrials.gov ID: NCT06514794

Public ClinicalTrials.gov record NCT06514794. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 16, 2026, 1:51 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in Patients With Relapsed/Refractory Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma (T-RRex)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The T-RRex study evaluates the efficacy of WU-CART-007 for patients with Relapsed/Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia (T-ALL)/Lymphoblastic Lymphoma (LBL) and to WU-CART-007 as a therapy to induce complete Minimum Residual Disease (MRD) negative response

Study identification

NCT ID: NCT06514794
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Allotera Therapeutics; Industry
Enrollment: 125 participants

Conditions and interventions

Conditions

Interventions

WU-CART-007 Biological

Biological

Eligibility (public fields only)

Age range: 6 Months and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jan 31, 2025 (Actual)
Primary completion: Dec 30, 2026 (Estimated)
Completion: Dec 30, 2028 (Estimated)
Last update posted: Sep 28, 2026

2025 – 2028

United States locations

U.S. sites: 16
U.S. states: 13
U.S. cities: 15

Facility	City	State	ZIP	Site status
City of Hope	Duarte	California	91010	Recruiting
Children's Hospital Los Angeles	Los Angeles	California	90027	Recruiting
Colorado Blood Cancer Institute	Denver	Colorado	80218	Recruiting
Children's National Hospital	Washington D.C.	District of Columbia	20010	Recruiting
H. Lee Moffitt Cancer Center and Research Institute Hospital	Tampa	Florida	33612	Recruiting
Children's Hospital of Atlanta	Atlanta	Georgia	30329	Recruiting
Washington University Saint Louis	St Louis	Missouri	63108	Recruiting
Memorial Sloan Kettering Cancer Center -- Pediatrics	New York	New York	10017	Recruiting
Oncology Hematology Care	Cincinnati	Ohio	45226	Recruiting
Cincinnati Children's Hospital Medical Center	Cincinnati	Ohio	45229	Recruiting
Children's Hospital of Philadelphia	Philadelphia	Pennsylvania	19390	Recruiting
TriStar Bone Marrow Transplant / Sarah Cannon Transplant & Cellular Therapy	Nashville	Tennessee	37203	Recruiting
MD Anderson Cancer Center	Houston	Texas	77030	Recruiting
Sarah Cannon Transplant and Cellular Therapy Methodist Hospital	San Antonio	Texas	78229	Recruiting
Sarah Cannon, Virginia Oncology Associates	Norfolk	Virginia	23502	Recruiting
Seattle Children's Hospital	Seattle	Washington	98105	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06514794, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Sep 28, 2026 · Synced Oct 16, 2026

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT06514794 live on ClinicalTrials.gov.

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