A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 85 Years With gMG.
Public ClinicalTrials.gov record NCT06517758. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled Phase III Study to Evaluate the Efficacy, Safety, and Tolerability of Iptacopan in Patients With Generalized Myasthenia Gravis, Followed by an Open-label Extension Phase
Study identification
- NCT ID
- NCT06517758
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 146 participants
Conditions and interventions
Conditions
Interventions
- Iptacopan Drug
- Matching Placebo Other
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 30, 2024
- Primary completion
- Apr 29, 2027
- Completion
- May 26, 2032
- Last update posted
- May 13, 2026
2024 – 2032
United States locations
- U.S. sites
- 19
- U.S. states
- 13
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Honor Health Research Institute | Scottsdale | Arizona | 85258 | Recruiting |
| Fullerton Neuro and Headache Ctr | Fullerton | California | 92835 | Recruiting |
| SC3 Research Pasadena | Pasadena | California | 91105 | Recruiting |
| California Pacific Medical Center | Sacramento | California | 94115 | Recruiting |
| Neurology Offices Of South Florida | Boca Raton | Florida | 33428 | Withdrawn |
| Superior Associates in Research LLC | Hialeah | Florida | 33012 | Withdrawn |
| Augusta University Georgia | Augusta | Georgia | 30912 | Recruiting |
| Hawaii Pacific Neuroscience LLC | Honolulu | Hawaii | 96817 | Withdrawn |
| University of Chicago Medical Centr | Chicago | Illinois | 60637 | Recruiting |
| Prairie Heart Institute | Springfield | Illinois | 62769 | Recruiting |
| Mid Atlantic Epilepsy and Sleep Ctr | Bethesda | Maryland | 20817-1807 | Recruiting |
| Duke University Medical Center | Durham | North Carolina | 27710 | Recruiting |
| Neuroscience Research Ctr | Canton | Ohio | 44718 | Withdrawn |
| Ohio State University Medical Center | Columbus | Ohio | 43210 | Withdrawn |
| Penn Presbyterian Medical Center | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Vanderbilt University Medical CenterX | Nashville | Tennessee | 37221 | Recruiting |
| Nerve and Muscle Center of Texas | Houston | Texas | 77030 | Recruiting |
| Central TX Neuro Consultants P A | Round Rock | Texas | 78681 | Recruiting |
| Center for Neurological Disorders G | Greenfield | Wisconsin | 53228-1321 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 94 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06517758, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 13, 2026 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06517758 live on ClinicalTrials.gov.