The Study of 177Lu-TLX591 Plus SOC Versus SOC Alone in Patients With mCRPC (ProstACT Global)
Public ClinicalTrials.gov record NCT06520345. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multinational, Multicenter, Prospective, Randomized, Controlled, Open-Label, Phase 3 Study of Lutetium (177Lu) Rosopatamab Tetraxetan in Combination With Standard of Care Versus Standard of Care Alone in Patients With PSMA Positive Metastatic Castration-Resistant Prostate Cancer Previously After Androgen Receptor Pathway Inhibitor Treatment
Study identification
- NCT ID
- NCT06520345
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Telix Pharmaceuticals (Innovations) Pty Limited
- Industry
- Enrollment
- 520 participants
Conditions and interventions
Interventions
- 177Lu-TLX591 Drug
- Abiraterone Drug
- Docetaxel Drug
- Enzalutamide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 25, 2024
- Primary completion
- Nov 30, 2027
- Completion
- Nov 30, 2030
- Last update posted
- May 4, 2026
2024 – 2030
United States locations
- U.S. sites
- 9
- U.S. states
- 8
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Chao Family Comprehensive Cancer Centre | Orange | California | 92868 | Active, not recruiting |
| Biogenix Molecular LLC | Miami | Florida | 33165 | Active, not recruiting |
| United Theranostics | Glen Burnie | Maryland | 21061 | Active, not recruiting |
| XCancer Omaha | Omaha | Nebraska | 68130 | Active, not recruiting |
| Columbia University Herbert Irving Comphrensive Cancer Center | New York | New York | 10032 | Recruiting |
| University Hospital | Cleveland | Ohio | 44106 | Active, not recruiting |
| OHSU Knight Cancer Center | Portland | Oregon | 97239 | Active, not recruiting |
| Intermountain Health | Murray | Utah | 84107 | Active, not recruiting |
| Intermountain Health | Salt Lake City | Utah | 84112 | Active, not recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 22 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06520345, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 4, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06520345 live on ClinicalTrials.gov.