Double-blind, Randomized, Placebo-controlled Study Evaluating Efficacy and Safety of IgPro20 in Post-COVID-19 POTS
Public ClinicalTrials.gov record NCT06524739. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Double-blind, Randomized, Placebo-controlled Phase 3 Study Evaluating Efficacy and Safety of IgPro20 (Subcutaneous Immunoglobulin, HIZENTRA®) in Post-COVID-19 Postural Orthostatic Tachycardia Syndrome (POTS)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a prospective, phase 3, multicenter, double-blind, randomized placebo-controlled study to investigate the efficacy, safety, and pharmacokinetics (PK) of repeat doses of IgPro20 in participants with post SARS-CoV-2 infection 2019 postural orthostatic tachycardia syndrome (post-Coronavirus Disease 2019 \[COVID-19\] POTS \[post-COVID-POTS\]).
Study identification
- NCT ID
- NCT06524739
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 16 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 28, 2024 (Actual)
- Primary completion
- Jun 20, 2025 (Actual)
- Completion
- Jul 11, 2025 (Actual)
- Last update posted
- Apr 13, 2026
2024 – 2025
United States locations
- U.S. sites
- 34
- U.S. states
- 22
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Hospital at Birmingham | Birmingham | Alabama | 35294-1152 | — |
| Center for Complex Neurology, EDS & POTS | Phoenix | Arizona | 85006 | — |
| Mayo Clinic Arizona | Scottsdale | Arizona | 85259 | — |
| Arkansas Cardiology Clinic - Little Rock | Little Rock | Arkansas | 72205 | — |
| UC San Diego Health | La Jolla | California | 92037 | — |
| University of california Irvine | Orange | California | 92868 | — |
| National Jewish Health | Denver | Colorado | 80206 | — |
| Hope Research Network | Miami | Florida | 33166 | — |
| Well Pharma Medical Research, Corp | Miami | Florida | 33173 | — |
| Velocity Clinical Research, Savannah | Savannah | Georgia | 31406 | — |
| LSU Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Velocity Clinical Research, Metairie | New Orleans | Louisiana | 70119 | — |
| Johns Hopkins Bayview Medical Center PMR | Baltimore | Maryland | 21224 | — |
| Mass General Brigham (Massachusetts General Hospital) | Belmont | Massachusetts | 02478 | — |
| Profound Research LLC at Millennium Affiliated Physicians | Farmington Hills | Michigan | 48334 | — |
| Velocity Clinical Research - Lincoln | Lincoln | Nebraska | 68510 | — |
| Dysautonomia Clinic | Buffalo | New York | 14221 | — |
| NYU Langone Health South Shore Neurologic Associates | Patchogue | New York | 11772 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Bernstein Clinical Research Center | Cincinnati | Ohio | 45236 | — |
| University Hospital Cleveland Medical Center | Cleveland | Ohio | 44195 | — |
| Hightower Clinical | Oklahoma City | Oklahoma | 73134 | — |
| Penn Presbyterian Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| Velocity Clinical Research - Union | Union | South Carolina | 29379 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| UT Austin Dell Medical School | Austin | Texas | 78712 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Prolato Clinical Research Center | Houston | Texas | 77054 | — |
| Sunbeam Clinical Research | McKinney | Texas | 75069 | — |
| University of Texas Health Science Center | San Antonio | Texas | 78229 | — |
| Bateman Horne Center | Salt Lake City | Utah | 84102 | — |
| Metrodora Institute | West Valley City | Utah | 84119 | — |
| Velocity Clinical Research - Hampton | Hampton | Virginia | 23666 | — |
| VCU Health | Richmond | Virginia | 23219 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06524739, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 13, 2026 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06524739 live on ClinicalTrials.gov.