A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both
Public ClinicalTrials.gov record NCT06534411. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of Co-administered Cagrilintide and Semaglutide (CagriSema) 1.0 mg/1.0 mg s.c. Once Weekly Versus Tirzepatide 5 mg s.c. Once Weekly in Participants With Type 2 Diabetes Inadequately Controlled on Metformin, SGLT2 Inhibitor or Both
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will look at how much CagriSema lowers blood sugar and body weight in people with type 2 diabetes. CagriSema is a new investigational medicine. Doctors cannot yet prescribe CagriSema. CagriSema will be compared to a medicine called tirzepatide. Doctors can prescribe tirzepatide in some countries. Participants will either receive CagriSema or tirzepatide. Which treatment the participant will receive is decided by chance. For each participant, the study will last for up to 1 year and 4 months.
Study identification
- NCT ID
- NCT06534411
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,023 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 5, 2024 (Actual)
- Primary completion
- Jun 2, 2026 (Actual)
- Completion
- Jul 9, 2026 (Actual)
- Last update posted
- Oct 19, 2026
2024 – 2026
United States locations
- U.S. sites
- 54
- U.S. states
- 27
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cahaba Research | Pelham | Alabama | 35124 | — |
| Velocity Clinical Research-Phoenix | Phoenix | Arizona | 85006 | — |
| AES Tucson DRS | Tucson | Arizona | 85712 | — |
| Woodland Int. Research Group | Little Rock | Arkansas | 72211 | — |
| Velocity Clin Res-Chula Vista | Chula Vista | California | 91911 | — |
| John Muir Physicians Network | Concord | California | 94520 | — |
| Diabetes & Endocrine Specialists - La Mesa | La Mesa | California | 91942 | — |
| Velocity Clin Research LA | Los Angeles | California | 90017 | — |
| Desert Oasis Healthcare | Palm Springs | California | 92262 | — |
| Velocity Clin Res Santa Ana | Santa Ana | California | 92704 | — |
| Velocity Clin Res - Panorama | Van Nuys | California | 91405 | — |
| Optumcare Clinical Trials,LLC-Golden | Colorado Springs | Colorado | 80906 | — |
| FEME Medical LLC | Washington D.C. | District of Columbia | 20010 | — |
| Tampa Bay Medical Research | Clearwater | Florida | 33761 | — |
| AGA Clinical Trial | Hialeah | Florida | 33012 | — |
| Bioclinical Research Alliance | Miami | Florida | 33155 | — |
| New Horizon Research Center | Miami | Florida | 33165 | — |
| South Broward Research LLC | Miramar | Florida | 33027 | — |
| West Orange Endocrinology | Ocoee | Florida | 34761 | — |
| Optimal Research Sites | Orange City | Florida | 32763 | — |
| Center for Diab,Obes & Metab | Pembroke Pines | Florida | 33024 | — |
| Javara Inc. / Privia Medical Group Georgia LLC | Fayetteville | Georgia | 30214 | — |
| Clinical Invest Special_Gurnee | Gurnee | Illinois | 60031 | — |
| Iowa Diabetes & Endo Res Ctr | West Des Moines | Iowa | 50266 | — |
| Cotton-Oneill Diabetes and End | Topeka | Kansas | 66606-2806 | — |
| AES Minneapolis DRS | Richfield | Minnesota | 55423 | — |
| Velocity Clin Res Gulfport | Gulfport | Mississippi | 39503 | — |
| AES St. Louis DRS | St Louis | Missouri | 63141 | — |
| Univ of Nebraska Medical CTR | Omaha | Nebraska | 68198-3020 | — |
| Velocity Clin Res Albuquerque | Albuquerque | New Mexico | 87107 | — |
| Albany Medical College | Albany | New York | 12203 | — |
| Carteret Medical Group | Morehead City | North Carolina | 28557 | — |
| Piedmont Healthcare/Research | Statesville | North Carolina | 28625 | — |
| Lillestol Research LLC | Fargo | North Dakota | 58104 | — |
| Triad Research Institute | Norman | Oklahoma | 73072 | — |
| Circuit Clinical - PMSI | Pottstown | Pennsylvania | 19464 | — |
| Clinical Res Collaborative | Cumberland | Rhode Island | 02864 | — |
| Velocity Clin Res Providence | East Greenwich | Rhode Island | 02818 | — |
| Velocity Clin Res Gaffney | Gaffney | South Carolina | 29340 | — |
| Holston Medical Group | Kingsport | Tennessee | 37660 | — |
| Clinical Research Associates | Nashville | Tennessee | 37203 | — |
| Velocity Clin Res Austin | Austin | Texas | 78759 | — |
| Synexus Clin Res Dallas | Dallas | Texas | 75234 | — |
| UT Southwestern Med Center | Dallas | Texas | 75390 | — |
| JCCT- Juno NW Houston | Houston | Texas | 77040 | — |
| Synergy Groups Medical | Houston | Texas | 77061 | — |
| PlanIt Research, PLLC | Houston | Texas | 77079 | — |
| Sante Clinical Research | Kerrville | Texas | 78028 | — |
| Aeres Clinical Research | Laredo | Texas | 78041 | — |
| Biopharma Informatic, LLC | McAllen | Texas | 78503 | — |
| Privia Health Javara Clin Res. | Stephenville | Texas | 76401 | — |
| J.Lewis Research Inc | Salt Lake City | Utah | 84109 | — |
| Chrysalis Clinical Research | St. George | Utah | 84790 | — |
| TPMG Clinical Research | Newport News | Virginia | 23606 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 109 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06534411, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 19, 2026 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06534411 live on ClinicalTrials.gov.