A Study of Mevidalen (LY3154207) in Participants With Alzheimer's Disease
Public ClinicalTrials.gov record NCT06538116. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blinded Study to Evaluate the Efficacy and Safety of Mevidalen in Patients With Alzheimer's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to look at how safe the study drug (mevidalen) is and whether it works to alleviate symptoms when given to people with mild to moderate Alzheimer Disease (AD) dementia. This is done by looking at participants: thinking and memory (cognition), everyday activities and sleep, AD symptoms, physical activity, irritability or anxiety. The study is expected to last approximately 26 weeks and may include up to 14 visits.
Study identification
- NCT ID
- NCT06538116
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 304 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 26, 2024 (Actual)
- Primary completion
- May 1, 2026 (Actual)
- Completion
- May 11, 2026 (Actual)
- Last update posted
- Jun 18, 2026
2024 – 2026
United States locations
- U.S. sites
- 44
- U.S. states
- 16
- U.S. cities
- 43
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner Alzheimer's Institute | Phoenix | Arizona | 85006 | — |
| Baptist Health Center for Clinical Research LLC | Little Rock | Arkansas | 72205 | — |
| Profound Research LLC At The Neurology Center of Southern California | Carlsbad | California | 92011 | — |
| Neuropain Medical Center | Fresno | California | 93710 | — |
| Catalina Research Institute | Montclair | California | 91763 | — |
| California Neuroscience Research, LLC | Sherman Oaks | California | 91403 | — |
| JEM Research Institute | Atlantis | Florida | 33462 | — |
| Visionary Investigators Network | Aventura | Florida | 33180 | — |
| Excel Medical Clinical Trials, LLC Boca Raton dba Flourish Research | Boca Raton | Florida | 33434 | — |
| Vertex Clinical Research | Clermont | Florida | 34711 | — |
| Neuropsychiatric Research Center of Southwest Florida | Fort Myers | Florida | 33912 | — |
| Clinical Neuroscience Solutions, Inc. | Jacksonville | Florida | 32256 | — |
| Merritt Island Medical Research, LLC dba Flourish Research | Merritt Island | Florida | 32952 | — |
| Visionary Investigators Network | Miami | Florida | 33176 | — |
| Suncoast Clinical Research - New Port Richey | New Port Richey | Florida | 34652 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Charter Research, LLC | Orlando | Florida | 32803 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| Intercoastal Medical Group | Sarasota | Florida | 34239 | — |
| Brain Matters Research | Stuart | Florida | 34997 | — |
| Charter Research - The Villages | The Villages | Florida | 32162 | — |
| Premiere Research Institute at Palm Beach Neurology | West Palm Beach | Florida | 33407 | — |
| Conquest Research | Winter Park | Florida | 32789 | — |
| Accel Research Sites - NeuroStudies CRU | Decatur | Georgia | 30030 | — |
| CenExel iResearch Atlanta | Decatur | Georgia | 30030 | — |
| CenExel iResearch, LLC | Savannah | Georgia | 31405 | — |
| Hawaii Pacific Neuroscience | Honolulu | Hawaii | 96817 | — |
| Ascension Alexian Brothers | Elk Grove Village | Illinois | 60007 | — |
| Josephson, Wallack, Munshower Neurology, P.C. | Indianapolis | Indiana | 46256 | — |
| ActivMed Practices & Research, LLC | Methuen | Massachusetts | 01844 | — |
| QUEST Research Institute | Farmington Hills | Michigan | 48334 | — |
| CenExel Advanced Memory Research Institute of NJ | Toms River | New Jersey | 08755 | — |
| AMC Research, LLC dba Flourish Research | Matthews | North Carolina | 28105 | — |
| Eximia Clinical Research-NC, LLC | Raleigh | North Carolina | 27612 | — |
| Keystone Clinical Studies, LLC Philadelphia dba Flourish Research | Plymouth Meeting | Pennsylvania | 19462 | — |
| Clinical Neuroscience Solutions, Inc.Ta | Memphis | Tennessee | 38119 | — |
| Senior Adults Specialty Research | Austin | Texas | 78757 | — |
| Kerwin Medical Center | Dallas | Texas | 75231 | — |
| Cedar Health Research, LLC | Euless | Texas | 76040 | — |
| Clinical Trial Network LLC | Houston | Texas | 77074 | — |
| El Faro Health and Therapeutics | Rio Grande City | Texas | 78582 | — |
| Be Well Clinical Studies | Round Rock | Texas | 78681 | — |
| Clinical Trials of Texas, LLC San Antonio dba Flourish Research | San Antonio | Texas | 78229 | — |
| University of Washington Medical Center | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06538116, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 18, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06538116 live on ClinicalTrials.gov.