Comparative Effectiveness of Prophylactic ICD Versus Non-ICD Therapy
Public ClinicalTrials.gov record NCT06543446. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Comparative Effectiveness of Prophylactic ICD Versus Non-ICD Therapy in Contemporary Heart Failure Patients With a Low Risk for Arrhythmic Death
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The investigators aim to compare the risk of mortality of Non-implantable carioverter defibrillator (ICD) vs. ICD management in patients with heart failure with reduced ejection fraction (HFrEF).
Study identification
- NCT ID
- NCT06543446
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 3,290 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 4, 2025 (Actual)
- Primary completion
- Apr 30, 2026 (Actual)
- Completion
- Apr 30, 2026 (Actual)
- Last update posted
- May 12, 2026
2025 – 2026
United States locations
- U.S. sites
- 13
- U.S. states
- 10
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| MaineHealth | Portland | Maine | 04102 | — |
| Johns Hopkins University | Baltimore | Maryland | 21287 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Corewell Health | Grand Rapids | Michigan | 49503 | — |
| Minneapolis Heart Institute Foundation | Minneapolis | Minnesota | 55407 | — |
| Rutgers | New Brunswick | New Jersey | 08901 | — |
| The Valley Hospital | Paramus | New Jersey | 07652 | — |
| Northwell Health | New York | New York | 10075 | — |
| Nuvance Health Hudson Valley Cardiovascular Practice, PC | Poughkeepsie | New York | 12601 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Intermountain Health Care, Inc. | Salt Lake City | Utah | 84111 | — |
| University of Virginia Health System | Charlottesville | Virginia | 22902 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06543446, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 12, 2026 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06543446 live on ClinicalTrials.gov.