ClinicalTrials.gov record
Active, not recruiting Phase 2 Interventional

A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease

ClinicalTrials.gov ID: NCT06544616

Public ClinicalTrials.gov record NCT06544616. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 3, 2026, 1:55 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study, to Assess Efficacy, Safety and Immunogenicity of JNJ-64042056, a Phosphorylated Tau Targeted Active Immunotherapy, in Participants With Preclinical Alzheimer's Disease

Study identification

NCT ID
NCT06544616
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Janssen Pharmaceutica N.V., Belgium
Industry
Enrollment
498 participants

Conditions and interventions

Interventions

  • JNJ-64042056 Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
55 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 21, 2024
Primary completion
Jul 16, 2031
Completion
Jul 15, 2032
Last update posted
Feb 16, 2026

2024 – 2032

United States locations

U.S. sites
34
U.S. states
16
U.S. cities
34
Facility City State ZIP Site status
Xenoscience Inc. Phoenix Arizona 85004
Irvine Clinical Research Irvine California 92614
Esperanza Clinical Murrieta California 92562
Artemis Institute for Clinical Research Riverside California 92503
Artemis Institute for Clinical Research San Diego California 92123
Yale University School Of Medicine New Haven Connecticut 06510
JEM Research LLC Atlantis Florida 33462
Excel Medical Clinical Trials, LLC Boca Raton Florida 33434
K2 Medical Research Winter Garden Clermont Florida 34711
Clinical NeuroScience Solutions Inc Jacksonville Florida 32256
K2 Medical Research Lady Lake Florida 32159
K2 Medical Research Maitland Florida 32751
Merritt Island Medical Research, LLC Merritt Island Florida 32952
Headlands Research Orlando Orlando Florida 32806
Alzheimers Research and Treatment Center Stuart Florida 34997
K2 Medical Research Tampa Florida 33634
Charter Research The Villages Florida 32162
Alzheimers Research and Treatment Center Wellington Florida 33414
Palm Beach Neurology and Premier Research Institute West Palm Beach Florida 33407
Great Lakes Clinical Trials Chicago Illinois 60640
Great Lakes Clinical Trials Gurnee Illinois 60031
Quest Research Institute Farmington Hills Michigan 48334
Hattiesburg Clinic Hattiesburg Mississippi 39401
The Cognitive and Research Center of New Jersey LLC Springfield New Jersey 07081
Neurological Associates of Albany, PC Albany New York 12208
Velocity Clinical Research East Syracuse New York 13057
The Medical Research Network, LLC New York New York 10128
AMC Research, LLC Matthews North Carolina 28105
Valley Medical Research Centerville Ohio 45459-2785
Keystone Clinical Studies LLC Plymouth Meeting Pennsylvania 19462
Butler Hospital Providence Rhode Island 02906
Clinical Trials of Texas Inc San Antonio Texas 78229
Memory Clinic Inc Bennington Vermont 05201
University of Virginia Charlottesville Virginia 22903

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 56 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06544616, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 16, 2026 · Synced May 3, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06544616 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →