A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease
Public ClinicalTrials.gov record NCT06544616. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study, to Assess Efficacy, Safety and Immunogenicity of JNJ-64042056, a Phosphorylated Tau Targeted Active Immunotherapy, in Participants With Preclinical Alzheimer's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to assess whether JNJ-64042056 affects the spread and build up of tau (a protein in brain) when compared with placebo, using brain scan (tau PET) to determine results from specific areas of the brain.
Study identification
- NCT ID
- NCT06544616
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 55 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 55 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 21, 2024
- Primary completion
- Dec 21, 2026
- Completion
- Jan 4, 2027
- Last update posted
- Sep 24, 2026
2024 – 2027
United States locations
- U.S. sites
- 34
- U.S. states
- 16
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Xenoscience Inc. | Phoenix | Arizona | 85004 | — |
| Irvine Clinical Research | Irvine | California | 92614 | — |
| Esperanza Clinical | Murrieta | California | 92562 | — |
| Artemis Institute for Clinical Research Riverside | Riverside | California | 92503 | — |
| Artemis Institute for Clinical Research San Diego | San Diego | California | 92123 | — |
| Yale University School Of Medicine | New Haven | Connecticut | 06510 | — |
| JEM Research LLC | Atlantis | Florida | 33462 | — |
| Excel Medical Clinical Trials, LLC | Boca Raton | Florida | 33434 | — |
| K2 Medical Research Winter Garden | Clermont | Florida | 34711 | — |
| Clinical NeuroScience Solutions Inc | Jacksonville | Florida | 32256 | — |
| K2 Medical Research Lady Lake | Lady Lake | Florida | 32159 | — |
| K2 Medical Research Maitland | Maitland | Florida | 32751 | — |
| Merritt Island Medical Research, LLC | Merritt Island | Florida | 32952 | — |
| Headlands Research Orlando | Orlando | Florida | 32806 | — |
| Alzheimers Research and Treatment Center Stuart | Stuart | Florida | 34996 | — |
| K2 Medical Research Tampa | Tampa | Florida | 33634 | — |
| Charter Research | The Villages | Florida | 32162 | — |
| Alzheimers Research and Treatment Center Wellington | Wellington | Florida | 33414 | — |
| Palm Beach Neurology and Premier Research Institute | West Palm Beach | Florida | 33407 | — |
| Great Lakes Clinical Trials Chicago | Chicago | Illinois | 60640 | — |
| Great Lakes Clinical Trials Gurnee | Gurnee | Illinois | 60031 | — |
| Quest Research Institute | Farmington Hills | Michigan | 48334 | — |
| Hattiesburg Clinic | Hattiesburg | Mississippi | 39401 | — |
| The Cognitive and Research Center of New Jersey LLC | Springfield | New Jersey | 07081 | — |
| Neurological Associates of Albany, PC | Albany | New York | 12208 | — |
| Velocity Clinical Research East Syracuse | East Syracuse | New York | 13057 | — |
| The Medical Research Network, LLC | New York | New York | 10128 | — |
| AMC Research, LLC | Matthews | North Carolina | 28105 | — |
| Valley Medical Research | Centerville | Ohio | 45459-2785 | — |
| Keystone Clinical Studies LLC | Plymouth Meeting | Pennsylvania | 19462 | — |
| Butler Hospital | Providence | Rhode Island | 02906 | — |
| Clinical Trials of Texas Inc | San Antonio | Texas | 78229 | — |
| Memory Clinic Inc | Bennington | Vermont | 05201 | — |
| University of Virginia | Charlottesville | Virginia | 22903 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 56 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06544616, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 24, 2026 · Synced Sep 28, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06544616 live on ClinicalTrials.gov.