Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
Public ClinicalTrials.gov record NCT06547489. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Double-blind Evaluation of the Efficacy and Safety of Oral GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder in Adults
Study identification
- NCT ID
- NCT06547489
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Syndeio Biosciences, Inc
- Industry
- Enrollment
- 164 participants
Conditions and interventions
Conditions
Interventions
- Zelquistinel Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2, 2025
- Primary completion
- Aug 31, 2027
- Completion
- Nov 30, 2027
- Last update posted
- May 4, 2026
2025 – 2027
United States locations
- U.S. sites
- 34
- U.S. states
- 19
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | Recruiting |
| University of Alabama at Birmingham-Huntsville | Huntsville | Alabama | 35801 | Recruiting |
| Wr-Pri, Llc | Encino | California | 91316 | Withdrawn |
| Irvine Clinical Research | Irvine | California | 92614 | Recruiting |
| CalNeuro Research Group | Los Angeles | California | 90025 | Recruiting |
| Pacific Clinical Research Management Group LLC | Upland | California | 91786 | Terminated |
| Sunwise Clinical Research LLC | Walnut Creek | California | 94549 | Recruiting |
| MCB Clinical Research Centers, Inc. | Colorado Springs | Colorado | 80910 | Recruiting |
| Mountain View Clinical Research | Denver | Colorado | 80209 | Recruiting |
| University of Connecticut School of Medicine Psychiatry Department | Farmington | Connecticut | 06030 | Recruiting |
| Clinical Neuroscience Solutions, Inc. | Jacksonville | Florida | 32256 | Recruiting |
| D&H Pompano Research Center, LLC | Margate | Florida | 33063 | Recruiting |
| Premier Clinical Research Institute, Inc. | Miami | Florida | 33122 | Recruiting |
| Miami Dade Medical Research Institute | Miami | Florida | 33176 | Recruiting |
| Clinical Neuroscience Solutions, Inc. | Orlando | Florida | 32801 | Recruiting |
| CenExel iRS (iResearch Savannah) | Savannah | Georgia | 31405 | Recruiting |
| Revive Research Institute | Elgin | Illinois | 60123 | Withdrawn |
| KUMC-Wichita | Wichita | Kansas | 66160 | Recruiting |
| Quantum Research Associates Corp. | Louisville | Kentucky | 40218 | Recruiting |
| Boston Clinical Trials | Boston | Massachusetts | 02131 | Withdrawn |
| Mayflower Clinical | Russells Mills | Massachusetts | 02747 | Recruiting |
| Vector Clinical Trials | Las Vegas | Nevada | 89128 | Recruiting |
| Neurobehavioral Research, Inc. | Cedarhurst | New York | 11516 | Recruiting |
| Insight Clinical Trials LLC | Independence | Ohio | 44131 | Recruiting |
| Sooner Clinical Research, Inc. | Oklahoma City | Oklahoma | 73116 | Withdrawn |
| Lehigh Center for Clinical Research | Allentown | Pennsylvania | 18103 | Recruiting |
| Clinical Neuroscience Solutions, Inc. | Memphis | Tennessee | 38119 | Active, not recruiting |
| Austin Clinical Trial Partners | Austin | Texas | 78737 | Recruiting |
| InSite Clinical Research, LLC | DeSoto | Texas | 75115 | Recruiting |
| Baylor College of Medicine, Psychiatry and Behavioral Sciences | Houston | Texas | 77030 | Withdrawn |
| Clinical Trials of Texas LLC | San Antonio | Texas | 78229 | Withdrawn |
| Grayline Research Center | Wichita Falls | Texas | 76309 | Recruiting |
| Andes Clinical Research | Orem | Utah | 84097 | Recruiting |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | Withdrawn |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06547489, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 4, 2026 · Synced May 7, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06547489 live on ClinicalTrials.gov.