To Evaluate the Efficacy of CVN424 in Parkinson's Disease Participants With Motor Complications
Public ClinicalTrials.gov record NCT06553027. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 3, Randomized, Double-Blind, Placebo-Controlled Multicenter Study of CVN424 in Parkinson's Disease Patients With Motor Complications
Study identification
- NCT ID
- NCT06553027
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Cerevance
- Industry
- Enrollment
- 330 participants
Conditions and interventions
Conditions
Interventions
- CVN424 150 mg Drug
- CVN424 75 mg Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 30 Years and older
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 19, 2024
- Primary completion
- Jul 31, 2026
- Completion
- Jul 31, 2026
- Last update posted
- Apr 16, 2026
2024 – 2026
United States locations
- U.S. sites
- 53
- U.S. states
- 23
- U.S. cities
- 44
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Kirklin Clinic of UAB Hospital | Birmingham | Alabama | 35233 | — |
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| University of Alabama at Birmingham ALS Clinic | Birmingham | Alabama | 35294 | — |
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Muhammad Ali Parkinson Center | Phoenix | Arizona | 85013 | — |
| St. Joseph's Hospital and Medical Center | Phoenix | Arizona | 85013 | — |
| Parkinson's Research Centers of America - Orange county | Aliso Viejo | California | 92656 | — |
| Parkinson's Research Centers of America - Orange County | Newport Beach | California | 92663 | — |
| Parkinson's Research Centers of America - Palo Alto | Palo Alto | California | 94301 | — |
| CenExel Rocky Mountain Clinical Research | Englewood | Colorado | 80113 | — |
| David and Rhoda Chase Family Movement Disorders Center - Vernon | Vernon | Connecticut | 06066 | — |
| Parkinson's Disease and Movement Disorders Center of Boca Raton | Boca Raton | Florida | 33486 | — |
| SFM Clinical Research, LLC | Boca Raton | Florida | 33487 | — |
| K2 Medical Research | Maitland | Florida | 32751 | — |
| Renstar Medical Research | Ocala | Florida | 34471 | — |
| N1 Research LLc | Orlando | Florida | 32825 | — |
| Parkinson's Disease Center of SWFL | Port Charlotte | Florida | 33980 | — |
| University Clinical Research-DeLand, LLC d/b/a Accel Research Sites - Brain & Spine Institute | Port Orange | Florida | 32127 | — |
| USF Parkinson's Disease and Movement Disorders Center | Tampa | Florida | 33613 | — |
| Atlanta Neuroscience Institute | Atlanta | Georgia | 30327 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Kentucky, Dept of Neurology Kentucky Neuroscience Institute Research | Lexington | Kentucky | 40536 | — |
| Boston Clinical Trials | Boston | Massachusetts | 02131 | — |
| University of Michigan Dept. of Neurology | Ann Arbor | Michigan | 48109 | — |
| University of Michigan Hospital - Michigan Clinical Research Unit (MCRU) | Ann Arbor | Michigan | 48109 | — |
| Quest Research Institute | Farmington Hills | Michigan | 48334 | — |
| Boro Neurology | Hopewell | New Jersey | 08525 | — |
| Global Neurosciences Institute at Pennington | Pennington | New Jersey | 08534 | — |
| Parkinson's Research Centers of America - Long Island | Commack | New York | 11725 | — |
| Weill Cornell Medical College | New York | New York | 10021 | — |
| The Neurological Institute | Charlotte | North Carolina | 28204 | — |
| Duke Neurology Morreene Road Clinic | Durham | North Carolina | 27705 | — |
| Raleigh Neurology Associates | Raleigh | North Carolina | 27607 | — |
| Velocity Clinical Research | Raleigh | North Carolina | 27607 | — |
| Riverhills Healthcare, Inc dba Riverhills Neuroscience | Cincinnati | Ohio | 45212 | — |
| The Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | — |
| The Ohio State University - Martha Morehouse Medical Plaza | Columbus | Ohio | 43221 | — |
| The Movement Disorder Clinic of Oklahoma | Tulsa | Oklahoma | 74136 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Veracity Neuroscience LLC | Memphis | Tennessee | 38157 | — |
| Horizon Clinical Research Group | Cypress | Texas | 77429 | — |
| Texas Movement Disorder Specialists, PLLC | Georgetown | Texas | 78628 | — |
| Houston Methodist Neurological Institute | Houston | Texas | 77030 | — |
| Gill Neuroscience | Houston | Texas | 77065 | — |
| Central Texas Neurology Consultants | Round Rock | Texas | 78681 | — |
| Inova Parkinson's and Movement Disorders Center - Alexandria | Alexandria | Virginia | 22311 | — |
| Inova Neurology - Fairfax | Fairfax | Virginia | 22031 | — |
| Inova Fairfax Medical Campus | Falls Church | Virginia | 22042 | — |
| Henrico Doctors Neurology Associates, LLC | Richmond | Virginia | 23229 | — |
| EvergreenHealth Research Department | Kirkland | Washington | 98034 | — |
| Inland Northwest Research | Spokane | Washington | 99202 | — |
| Medical College of Wisconsin-Department of Neurology | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 41 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06553027, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 16, 2026 · Synced Apr 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06553027 live on ClinicalTrials.gov.