ClinicalTrials.gov record
Active, not recruiting Phase 3 Interventional

To Evaluate the Efficacy of CVN424 in Parkinson's Disease Participants With Motor Complications

ClinicalTrials.gov ID: NCT06553027

Public ClinicalTrials.gov record NCT06553027. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 22, 2026, 8:25 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 3, Randomized, Double-Blind, Placebo-Controlled Multicenter Study of CVN424 in Parkinson's Disease Patients With Motor Complications

Study identification

NCT ID
NCT06553027
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Cerevance
Industry
Enrollment
330 participants

Conditions and interventions

Interventions

  • CVN424 150 mg Drug
  • CVN424 75 mg Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
30 Years and older
Sex
All
Healthy volunteers
Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 19, 2024
Primary completion
Jul 31, 2026
Completion
Jul 31, 2026
Last update posted
Apr 16, 2026

2024 – 2026

United States locations

U.S. sites
53
U.S. states
23
U.S. cities
44
Facility City State ZIP Site status
The Kirklin Clinic of UAB Hospital Birmingham Alabama 35233
University of Alabama at Birmingham Birmingham Alabama 35233
University of Alabama at Birmingham ALS Clinic Birmingham Alabama 35294
Barrow Neurological Institute Phoenix Arizona 85013
Muhammad Ali Parkinson Center Phoenix Arizona 85013
St. Joseph's Hospital and Medical Center Phoenix Arizona 85013
Parkinson's Research Centers of America - Orange county Aliso Viejo California 92656
Parkinson's Research Centers of America - Orange County Newport Beach California 92663
Parkinson's Research Centers of America - Palo Alto Palo Alto California 94301
CenExel Rocky Mountain Clinical Research Englewood Colorado 80113
David and Rhoda Chase Family Movement Disorders Center - Vernon Vernon Connecticut 06066
Parkinson's Disease and Movement Disorders Center of Boca Raton Boca Raton Florida 33486
SFM Clinical Research, LLC Boca Raton Florida 33487
K2 Medical Research Maitland Florida 32751
Renstar Medical Research Ocala Florida 34471
N1 Research LLc Orlando Florida 32825
Parkinson's Disease Center of SWFL Port Charlotte Florida 33980
University Clinical Research-DeLand, LLC d/b/a Accel Research Sites - Brain & Spine Institute Port Orange Florida 32127
USF Parkinson's Disease and Movement Disorders Center Tampa Florida 33613
Atlanta Neuroscience Institute Atlanta Georgia 30327
University of Kansas Medical Center Kansas City Kansas 66160
University of Kentucky, Dept of Neurology Kentucky Neuroscience Institute Research Lexington Kentucky 40536
Boston Clinical Trials Boston Massachusetts 02131
University of Michigan Dept. of Neurology Ann Arbor Michigan 48109
University of Michigan Hospital - Michigan Clinical Research Unit (MCRU) Ann Arbor Michigan 48109
Quest Research Institute Farmington Hills Michigan 48334
Boro Neurology Hopewell New Jersey 08525
Global Neurosciences Institute at Pennington Pennington New Jersey 08534
Parkinson's Research Centers of America - Long Island Commack New York 11725
Weill Cornell Medical College New York New York 10021
The Neurological Institute Charlotte North Carolina 28204
Duke Neurology Morreene Road Clinic Durham North Carolina 27705
Raleigh Neurology Associates Raleigh North Carolina 27607
Velocity Clinical Research Raleigh North Carolina 27607
Riverhills Healthcare, Inc dba Riverhills Neuroscience Cincinnati Ohio 45212
The Ohio State University Wexner Medical Center Columbus Ohio 43210
The Ohio State University - Martha Morehouse Medical Plaza Columbus Ohio 43221
The Movement Disorder Clinic of Oklahoma Tulsa Oklahoma 74136
Oregon Health and Science University Portland Oregon 97239
Medical University of South Carolina Charleston South Carolina 29425
Veracity Neuroscience LLC Memphis Tennessee 38157
Horizon Clinical Research Group Cypress Texas 77429
Texas Movement Disorder Specialists, PLLC Georgetown Texas 78628
Houston Methodist Neurological Institute Houston Texas 77030
Gill Neuroscience Houston Texas 77065
Central Texas Neurology Consultants Round Rock Texas 78681
Inova Parkinson's and Movement Disorders Center - Alexandria Alexandria Virginia 22311
Inova Neurology - Fairfax Fairfax Virginia 22031
Inova Fairfax Medical Campus Falls Church Virginia 22042
Henrico Doctors Neurology Associates, LLC Richmond Virginia 23229
EvergreenHealth Research Department Kirkland Washington 98034
Inland Northwest Research Spokane Washington 99202
Medical College of Wisconsin-Department of Neurology Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 41 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06553027, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 16, 2026 · Synced Apr 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06553027 live on ClinicalTrials.gov.

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