THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
Public ClinicalTrials.gov record NCT06559891. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Pivotal, Prospective, Multicenter, 2:1 Randomized, Double Blind, Controlled, Study Comparing the THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension (The THRIVE Study)
Study identification
- NCT ID
- NCT06559891
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Lead sponsor
- SoniVie Inc.
- Industry
- Enrollment
- 261 participants
Conditions and interventions
Conditions
Interventions
- Sham Other
- TIVUS™ Renal Denervation System Device
Other · Device
Eligibility (public fields only)
- Age range
- 22 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2, 2024
- Primary completion
- Mar 30, 2027
- Completion
- Aug 14, 2028
- Last update posted
- May 4, 2026
2024 – 2028
United States locations
- U.S. sites
- 33
- U.S. states
- 21
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cardiology, PC | Birmingham | Alabama | 35211 | Recruiting |
| Honor Health Research Institue | Scottsdale | Arizona | 85258 | Recruiting |
| St. Bernard's Medical Center | Jonesboro | Arkansas | 72401 | Recruiting |
| Arkansas Heart Hospital | Little Rock | Arkansas | 72211 | Recruiting |
| Cedar-Sinai Medical Center | Los Angeles | California | 90048 | Recruiting |
| Stanford University | Palo Alto | California | 94305 | Recruiting |
| Bridgeport | Bridgeport | Connecticut | 06610 | Recruiting |
| Ascension- Sacred Heart | Pensecola | Florida | 32504 | Recruiting |
| University of South Florida | Tampa | Florida | 33606 | Recruiting |
| Ascension Alexian Brothers | Elk Grove Village | Illinois | 60007 | Recruiting |
| St. John's Prairie Heart | Springfield | Illinois | 62710 | Recruiting |
| Southern Illinois University, School of Medicine | Springfield | Illinois | 62794 | Recruiting |
| Cardiovascular Institute of the South | Houma | Louisiana | 70360 | Recruiting |
| Ochsner Medical Center | New Orleans | Louisiana | 70121 | Recruiting |
| Henry Ford Hospital | Detroit | Michigan | 48202 | Recruiting |
| Henry Ford Providence Hospital | Southfield | Michigan | 48075 | Recruiting |
| Gulfport Memorial Hospital | Gulfport | Mississippi | 39501 | Recruiting |
| Jackson Heart | Jackson | Mississippi | 39216 | Recruiting |
| St Lukes Hospital | Kansas City | Missouri | 64131 | Recruiting |
| Renown Regional Medical Center | Reno | Nevada | 89502 | Recruiting |
| Virtua Health | Camden | New Jersey | 08103 | Recruiting |
| Jersey Shore University Medical Center | Neptune City | New Jersey | 07753 | Recruiting |
| St. Joseph | Liverpool | New York | 13088 | Recruiting |
| Nyph/Cumc | New York | New York | 10032 | Recruiting |
| NC Heart and Vascular | Raleigh | North Carolina | 27607 | Recruiting |
| Ascension St. John Clinical Research Institute | Bartlesville | Oklahoma | 74006 | Recruiting |
| Lancaster General Health | Lancaster | Pennsylvania | 17603 | Recruiting |
| Penn Medicine | Philadelphia | Pennsylvania | 19104 | Recruiting |
| MUSC | Mt. Pleasant | South Carolina | 29464 | Recruiting |
| Medical City | Fort Worth | Texas | 76104 | Recruiting |
| Houston Medical Center | Houston | Texas | 77004 | Recruiting |
| St Marks Hospital | Salt Lake City | Utah | 37027 | Recruiting |
| Chippenham Hospital | Richmond | Virginia | 23225 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06559891, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 4, 2026 · Synced May 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06559891 live on ClinicalTrials.gov.