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Recruiting Phase 4 Interventional

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

ClinicalTrials.gov ID: NCT06562543

Public ClinicalTrials.gov record NCT06562543. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 11, 2026, 8:02 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Single Arm Phase 4 Trial to Evaluate the Safety and Efficacy of Oral Fruquintinib in the Treatment of Refractory Metastatic Colorectal Cancer in Patients From Minority Populations Underrepresented in Prior Fruquintinib Studies

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

High blood pressure (hypertension) is a known side effect of the treatment with fruquintinib. Current research does not provide a clear answer whether minority groups such as Black/African American and/or Hispanic/Latino with refractory metastatic colorectal cancer (mCRC) have a bigger risk of higher blood pressure after treatment with fruquintinib. The main aim of this study is to learn how often adults of a minority group experience hypertension after they have been treated with fruquintinib for refractory mCRC. Other aims are to learn how safe fruquintinib is and how well it is tolerated by participants. Participants will receive fruquintinib in 4-week treatment cycles until their condition worsens, they do no longer tolerate the treatment or stop the treatment for other reasons. After the last treatment, participants will be checked upon every 3 months until study completion.

Study identification

NCT ID
NCT06562543
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 4
Lead sponsor
Takeda
Industry
Enrollment
78 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 13, 2025
Primary completion
Oct 3, 2027
Completion
Oct 3, 2027
Last update posted
Jul 6, 2026

2025 – 2027

United States locations

U.S. sites
44
U.S. states
23
U.S. cities
37
Facility City State ZIP Site status
Central Alabama Research Birmingham Alabama 35209 Recruiting
University of Alabama at Birmingham Birmingham Alabama 35249 Recruiting
Ironwood Cancer and Research Centers Chandler Arizona 85224 Recruiting
University of Arizona Tucson Arizona 85719 Recruiting
University of California San Diego La Jolla California 92093 Recruiting
University of Southern California Los Angeles California 90033 Recruiting
PIH Health Whittier Hospital Whittier California 90602 Recruiting
Christiana Care Health Services Newark Delaware 19713 Recruiting
University of Florida Gainesville Florida 32610 Completed
University of Miami Miami Florida 33146 Withdrawn
Baptist Health - Miami Cancer Institute Miami Florida 33176 Withdrawn
Emory University Atlanta Georgia 30322 Recruiting
Hope and Healing Cancer Services Hinsdale Illinois 60521 Recruiting
Indiana University Indianapolis Indiana 46202 Recruiting
Our Lady of the Lake Physician Group - LSU Health Baton Rouge Oncology Baton Rouge Louisiana 70805 Recruiting
Willis Knighton Cancer Center Shreveport Louisiana 71103 Recruiting
Mercy Medical Center Baltimore Maryland 21202 Recruiting
Boston Medical Center Boston Massachusetts 02118 Withdrawn
Hattiesburg Clinic Hattiesburg Mississippi 39401 Recruiting
Saint Luke's Cancer Institute Kansas City Missouri 64111 Withdrawn
Midwest Oncology Associates - Kansas City Kansas City Missouri 64132 Recruiting
SSM Health St. Louis DePaul Hospital St Louis Missouri 63044 Recruiting
Washington University School of Medicine St Louis Missouri 63108 Recruiting
Capital Health Medical Center - Hopewell Pennington New Jersey 08534 Recruiting
Columbia University New York New York 10032 Withdrawn
Albert Einstein College of Medicine The Bronx New York 10461 Withdrawn
James J Peters Veterans Administration Medical Center - NAVREF The Bronx New York 10468 Withdrawn
Zangmeister Cancer Center Columbus Ohio 43219 Recruiting
Hightower Clinical Research Oklahoma City Oklahoma 73102 Completed
Jefferson Health Philadelphia Pennsylvania 19107 Recruiting
Fox Chase Cancer Center | Philadelphia, PA Philadelphia Pennsylvania 19111 Withdrawn
Medical University of South Carolina Charleston South Carolina 29425 Withdrawn
University of Tennessee -- Memphis Memphis Tennessee 38163 Recruiting
Vanderbilt University Medical Center Nashville Tennessee 37212 Recruiting
University of Texas Southwestern Medical Center Dallas Texas 75390 Recruiting
Renovatio Clinical El Paso Texas 79915 Recruiting
Oncology Consultants - Memorial City Location Houston Texas 77030 Recruiting
Baylor College of Medicine Houston Texas 77054 Recruiting
BRCR Global Katy Texas 77450 Withdrawn
Renovatio Clinical The Woodlands Texas 77380 Recruiting
Tranquil Research Webster Texas 77598 Recruiting
UC Irvine Medical Center - Chao Family Comprehensive Cancer Orange Virginia 22960 Recruiting
Virginia Commonwealth University Richmond Virginia 23298 Recruiting
Medstar Speciality Hospital Northwest Washington 20010 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06562543, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 6, 2026 · Synced Sep 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06562543 live on ClinicalTrials.gov.

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