A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer
Public ClinicalTrials.gov record NCT06562543. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Single Arm Phase 4 Trial to Evaluate the Safety and Efficacy of Oral Fruquintinib in the Treatment of Refractory Metastatic Colorectal Cancer in Patients From Minority Populations Underrepresented in Prior Fruquintinib Studies
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
High blood pressure (hypertension) is a known side effect of the treatment with fruquintinib. Current research does not provide a clear answer whether minority groups such as Black/African American and/or Hispanic/Latino with refractory metastatic colorectal cancer (mCRC) have a bigger risk of higher blood pressure after treatment with fruquintinib. The main aim of this study is to learn how often adults of a minority group experience hypertension after they have been treated with fruquintinib for refractory mCRC. Other aims are to learn how safe fruquintinib is and how well it is tolerated by participants. Participants will receive fruquintinib in 4-week treatment cycles until their condition worsens, they do no longer tolerate the treatment or stop the treatment for other reasons. After the last treatment, participants will be checked upon every 3 months until study completion.
Study identification
- NCT ID
- NCT06562543
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 78 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 13, 2025
- Primary completion
- Oct 3, 2027
- Completion
- Oct 3, 2027
- Last update posted
- Jul 6, 2026
2025 – 2027
United States locations
- U.S. sites
- 44
- U.S. states
- 23
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Central Alabama Research | Birmingham | Alabama | 35209 | Recruiting |
| University of Alabama at Birmingham | Birmingham | Alabama | 35249 | Recruiting |
| Ironwood Cancer and Research Centers | Chandler | Arizona | 85224 | Recruiting |
| University of Arizona | Tucson | Arizona | 85719 | Recruiting |
| University of California San Diego | La Jolla | California | 92093 | Recruiting |
| University of Southern California | Los Angeles | California | 90033 | Recruiting |
| PIH Health Whittier Hospital | Whittier | California | 90602 | Recruiting |
| Christiana Care Health Services | Newark | Delaware | 19713 | Recruiting |
| University of Florida | Gainesville | Florida | 32610 | Completed |
| University of Miami | Miami | Florida | 33146 | Withdrawn |
| Baptist Health - Miami Cancer Institute | Miami | Florida | 33176 | Withdrawn |
| Emory University | Atlanta | Georgia | 30322 | Recruiting |
| Hope and Healing Cancer Services | Hinsdale | Illinois | 60521 | Recruiting |
| Indiana University | Indianapolis | Indiana | 46202 | Recruiting |
| Our Lady of the Lake Physician Group - LSU Health Baton Rouge Oncology | Baton Rouge | Louisiana | 70805 | Recruiting |
| Willis Knighton Cancer Center | Shreveport | Louisiana | 71103 | Recruiting |
| Mercy Medical Center | Baltimore | Maryland | 21202 | Recruiting |
| Boston Medical Center | Boston | Massachusetts | 02118 | Withdrawn |
| Hattiesburg Clinic | Hattiesburg | Mississippi | 39401 | Recruiting |
| Saint Luke's Cancer Institute | Kansas City | Missouri | 64111 | Withdrawn |
| Midwest Oncology Associates - Kansas City | Kansas City | Missouri | 64132 | Recruiting |
| SSM Health St. Louis DePaul Hospital | St Louis | Missouri | 63044 | Recruiting |
| Washington University School of Medicine | St Louis | Missouri | 63108 | Recruiting |
| Capital Health Medical Center - Hopewell | Pennington | New Jersey | 08534 | Recruiting |
| Columbia University | New York | New York | 10032 | Withdrawn |
| Albert Einstein College of Medicine | The Bronx | New York | 10461 | Withdrawn |
| James J Peters Veterans Administration Medical Center - NAVREF | The Bronx | New York | 10468 | Withdrawn |
| Zangmeister Cancer Center | Columbus | Ohio | 43219 | Recruiting |
| Hightower Clinical Research | Oklahoma City | Oklahoma | 73102 | Completed |
| Jefferson Health | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Fox Chase Cancer Center | Philadelphia, PA | Philadelphia | Pennsylvania | 19111 | Withdrawn |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | Withdrawn |
| University of Tennessee -- Memphis | Memphis | Tennessee | 38163 | Recruiting |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37212 | Recruiting |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | Recruiting |
| Renovatio Clinical | El Paso | Texas | 79915 | Recruiting |
| Oncology Consultants - Memorial City Location | Houston | Texas | 77030 | Recruiting |
| Baylor College of Medicine | Houston | Texas | 77054 | Recruiting |
| BRCR Global | Katy | Texas | 77450 | Withdrawn |
| Renovatio Clinical | The Woodlands | Texas | 77380 | Recruiting |
| Tranquil Research | Webster | Texas | 77598 | Recruiting |
| UC Irvine Medical Center - Chao Family Comprehensive Cancer | Orange | Virginia | 22960 | Recruiting |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | Recruiting |
| Medstar Speciality Hospital | Northwest | Washington | 20010 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06562543, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 6, 2026 · Synced Sep 11, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06562543 live on ClinicalTrials.gov.