ClinicalTrials.gov record
Evaluation of Efficacy of Povetacicept in Adults With Immunoglobulin A Nephropathy (IgAN)
ClinicalTrials.gov ID: NCT06564142
Public ClinicalTrials.gov record NCT06564142. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Povetacicept in Adults With Immunoglobulin A Nephropathy (RAINIER)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy of povetacicept in adult participants compared with placebo in reducing proteinuria and preserving renal function.
Study identification
- NCT ID
- NCT06564142
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 605 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 30, 2024 (Actual)
- Primary completion
- Jan 30, 2028 (Estimated)
- Completion
- Jan 30, 2028 (Estimated)
- Last update posted
- May 15, 2026
2024 – 2028
United States locations
- U.S. sites
- 77
- U.S. states
- 32
- U.S. cities
- 70
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Apogee Clinical Research, LLC | Huntsville | Alabama | 35805 | — |
| Arizona Kidney Disease and Hypertension Center - Thomas Office | Phoenix | Arizona | 85016 | — |
| Arizona Kidney Disease and Hypertension Center - Tuscon | Tucson | Arizona | 85741 | — |
| West Coast Kidney | Fremont | California | 94538 | — |
| The Medical Research Group, Inc. (FRENOVA) | Fresno | California | 93720 | — |
| CARE Institute - Carabello Kidney | Los Angeles | California | 90022 | — |
| Providence Medical Foundation - Orange | Orange | California | 92868 | — |
| National Nephrology Alliance Research | Riverside | California | 92505 | — |
| UC Davis Health | Sacramento | California | 95819 | — |
| Zuckerberg San Francisco General Hospital and Trauma Center | San Francisco | California | 94110 | — |
| University of California San Francisco (UCSF) | San Francisco | California | 94143 | — |
| Western Nephrology | Arvada | Colorado | 80002 | — |
| Colorado Kidney Care | Denver | Colorado | 80230 | — |
| Nephrology Associates Delaware Kidney (FRENOVA) | Newark | Delaware | 19713 | — |
| South Florida Nephrology Group PA, Research Div. | Coral Springs | Florida | 33071 | — |
| Dolphin Medical Research | Doral | Florida | 33172 | — |
| Nephrology Associates of Central Florida | Hollywood | Florida | 32806 | — |
| Tectum Medical Research, LLC | Hollywood | Florida | 33024 | — |
| South Florida Research Institute | Lauderdale Lakes | Florida | 33313 | — |
| Florida Kidney Physicians - Melbourne | Melbourne | Florida | 32901 | — |
| Med-Care Research | Miami | Florida | 33125 | — |
| Professional Research Center | Miami | Florida | 33172 | — |
| Nephrology Associates of South Miami | Miami | Florida | 33173 | — |
| On Health Research Center | Miami | Florida | 33186 | — |
| Combined Research Orlando Phase I-IV | Orlando | Florida | 32807 | — |
| BioResearch Partner | Pembroke Pines | Florida | 33029 | — |
| D&H Pompano Research Center | Pompano Beach | Florida | 33064 | — |
| Cordova Research Institute, LLC | Sweetwater | Florida | 33182 | — |
| SciMerge Clinical Research | Atlanta | Georgia | 30274 | — |
| Georgia Nephrology - Lawrenceville | Lawrenceville | Georgia | 30046 | — |
| Randomize Now - Midtown | Newnan | Georgia | 30269 | — |
| Care Institute - Chubbuck, ID | Chubbuck | Idaho | 83202 | — |
| Care Institute - Idaho Falls | Idaho Falls | Idaho | 83404 | — |
| CARE - Boise Kidney Institute | Meridian | Idaho | 83642 | — |
| Bioluminux Clinical Research | Naperville | Illinois | 60540 | — |
| Rockford Nephrology Associates | Rockford | Illinois | 61107 | — |
| Nephrology Associates of Northern Illinois and Indiana (NANI) | Indianapolis | Indiana | 46227 | — |
| Nephrology Physicians LLC | Mishawaka | Indiana | 46545 | — |
| Nephrology Associates of Kentuckiana | Louisville | Kentucky | 40205 | — |
| Renal Associates of Baton Rouge | Baton Rouge | Louisiana | 70808 | — |
| Velocity Clinical Research - Metairie | Metairie | Louisiana | 70006 | — |
| Johns Hopkins School of Medicine | Baltimore | Maryland | 21287 | — |
| St. Clair Nephrology Research | Shelby | Michigan | 48315 | — |
| InterMed Consultants / DaVita Clinical Research, Edina | Edina | Minnesota | 55404 | — |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | — |
| Nephrology and Hypertension Associates, LTD | Tupelo | Mississippi | 38801 | — |
| Washington University in St. Louis | St Louis | Missouri | 63110 | — |
| Somnos Clinical Research | Lincoln | Nebraska | 68505 | — |
| DaVita Clinical Research Nevada - Las Vegas | Las Vegas | Nevada | 89129 | — |
| Bioluminux Clinical Research New Jersey | Hamilton | New Jersey | 08690 | — |
| New Jersey Kidney Care, LLC (FRENOVA) | Jersey City | New Jersey | 07305 | — |
| Renal Medicine Associates | Albuquerque | New Mexico | 87109 | — |
| New York Nephrology Vasculitis and Glomerular Center | Albany | New York | 12209 | — |
| Queens Hospital Center | Jamaica | New York | 11432 | — |
| The Rogosin Institute | New York | New York | 10021 | — |
| Metrolina Nephrology Associates | Charlotte | North Carolina | 28208 | — |
| The Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Nephrology Associates Inc | East Providence | Rhode Island | 02914 | — |
| Hypertension & Nephrology Inc. | Providence | Rhode Island | 02904 | — |
| South Carolina Clinical Research, LLC | Orangeburg | South Carolina | 29118 | — |
| Knoxville Kidney Center (KKC), PLLC | Knoxville | Tennessee | 37923 | — |
| Velocity Clinical Research | Abilene | Texas | 79606 | — |
| Introscience Research LLC | Bellaire | Texas | 77401 | — |
| Dallas Renal Group | Dallas | Texas | 75230 | — |
| Renal Disease Research Institute - Dallas | Dallas | Texas | 75264 | — |
| Davita Clinical Research - El Paso | El Paso | Texas | 79925 | — |
| Prolato Clinical Research Center | Houston | Texas | 77054 | — |
| Houston Medical Research Institute, LLC (FRENOVA) | Houston | Texas | 77074 | — |
| R & H Clinical Research | Katy | Texas | 77450 | — |
| North Texas Kidney Disease Associates | Lewisville | Texas | 75057 | — |
| P&I Clinical Research, LLC | Lufkin | Texas | 75904 | — |
| Renal Specialists of Houston | Pasadena | Texas | 77504 | — |
| Utah Kidney Research Institute | Salt Lake City | Utah | 84115 | — |
| University of Vermont | Burlington | Vermont | 05401 | — |
| Virginia Nephrology Group | Fairfax | Virginia | 22101 | — |
| Kidney and Hypertension Specialist PLLC | Manassas | Virginia | 20110 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 241 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06564142, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 15, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06564142 live on ClinicalTrials.gov.