ClinicalTrials.gov record
"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"
ClinicalTrials.gov ID: NCT06564818
Public ClinicalTrials.gov record NCT06564818. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 8, 2026, 8:08 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Placebo-Controlled, Randomized, Double-Blind Trial of Oral Doses of CYB003 to Assess Combined Safety and Efficacy in Humans With Major Depressive Disorder
Study identification
- NCT ID
- NCT06564818
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Cybin IRL Limited
- Industry
- Enrollment
- 220 participants
Conditions and interventions
Conditions
Interventions
- CYB003 Drug
- Placebo Drug
- Psychological Support Behavioral
Drug · Behavioral
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 16, 2024
- Primary completion
- Jul 31, 2026
- Completion
- Aug 31, 2026
- Last update posted
- May 5, 2026
2024 – 2026
United States locations
- U.S. sites
- 46
- U.S. states
- 17
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Scottsdale Research Institute | Phoenix | Arizona | 85022 | Recruiting |
| Mountain Clinical Trials | Phoenix | Arizona | 85050 | Recruiting |
| Noble Clinical Research | Tucson | Arizona | 85704 | Recruiting |
| Del Sol Research Management | Tucson | Arizona | 85715 | Recruiting |
| CenExel CIT (Clinical Innovations, Inc) | Bellflower | California | 90706 | Recruiting |
| Kadima Neuropsychiatry Institute | La Jolla | California | 92037 | Recruiting |
| Bespoke Treatment/Lipov Medical Group | Los Angeles | California | 90025 | Recruiting |
| Catalina Research Institute | Montclair | California | 91763 | Recruiting |
| Excell Research, Inc | Oceanside | California | 92056 | Recruiting |
| Open Mind Therapeutics | San Francisco | California | 94114 | Recruiting |
| Inland Psychiatric Medical Group Inc | San Juan Capistrano | California | 92675 | Recruiting |
| Mountain View Clinical Research | Denver | Colorado | 80209 | Recruiting |
| Starlight Clinical Research | Evergreen | Colorado | 80439 | Recruiting |
| Research Centers of America | Hollywood | Florida | 33024 | Recruiting |
| K2 Medical Research-Maitland | Maitland | Florida | 32751 | Recruiting |
| Floridian Neuroscience Institute | Miami | Florida | 33135 | Recruiting |
| Segal Trials West Broward | North Miami | Florida | 33161 | Recruiting |
| Clinical Neuroscience Solutions, Inc | Orlando | Florida | 32801 | Recruiting |
| Charter Research | Orlando | Florida | 32803 | Recruiting |
| Combined Research Orlando Phase I-IV | Orlando | Florida | 32807 | Recruiting |
| K2 Medical Research - Tampa | Tampa | Florida | 33634 | Recruiting |
| Atlanta Center for Medical Research, CenExel | Atlanta | Georgia | 30331 | Recruiting |
| CenExel iResearch Atlanta | Decatur | Georgia | 30330 | Recruiting |
| CenExel iResearch Savannah | Savannah | Georgia | 31405 | Recruiting |
| Great Lakes Clinical Trials, DBA Flourish Research | Chicago | Illinois | 60640 | Recruiting |
| Uptown Research Institute | Chicago | Illinois | 60640 | Recruiting |
| Psychiatric Medicine Associates, LLC | Skokie | Illinois | 60076 | Recruiting |
| Atlas Psychiatric | New Orleans | Louisiana | 70115 | Not yet recruiting |
| DelRicht Research | New Orleans | Louisiana | 70115 | Recruiting |
| Sunstone Medical, PC | Rockville | Maryland | 20850 | Recruiting |
| Adams Clinical Boston | Boston | Massachusetts | 02116 | Recruiting |
| Adams Clinical | Boston | Massachusetts | 02472 | Recruiting |
| Elixia Health | Springfield | Massachusetts | 01103 | Recruiting |
| Redbird Research, LLC | Las Vegas | Nevada | 89119 | Recruiting |
| Oasis Clinical Trials | Las Vegas | Nevada | 89121 | Terminated |
| Global Medical Institutes, Princeton Medical Institute | Princeton | New Jersey | 08540 | Recruiting |
| Adams Clinical Harlem | New York | New York | 100029 | Recruiting |
| Adams Clinical Bronx | The Bronx | New York | 10461 | Recruiting |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | Recruiting |
| Neurobehavioral Clinical Research | North Canton | Ohio | 44720 | Recruiting |
| Clinical Neuroscience Solutions, CNS Healthcare | Memphis | Tennessee | 38119 | Recruiting |
| InSite Clinical Research, LLC | DeSoto | Texas | 75115 | Recruiting |
| Zillan Clinical Research | Houston | Texas | 77433 | Recruiting |
| AIM Trials | Plano | Texas | 75093 | Withdrawn |
| Cedar Clinical Research | Murray | Utah | 84107 | Recruiting |
| Inner Space Research, LLC | Orem | Utah | 84058 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06564818, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 5, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06564818 live on ClinicalTrials.gov.