ClinicalTrials.gov record
A Study to Evaluate the Efficacy and Safety of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DME
ClinicalTrials.gov ID: NCT06571045
Public ClinicalTrials.gov record NCT06571045. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 8, 2026, 3:54 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Masked, Multi-Center, 3-Arm Pivotal Phase 2/3 Study to Evaluate The Efficacy and Safety of Intravitreal EYE103 Compared With Intravitreal Ranibizumab (0.5mg) in Participants With Diabetic Macular Edema
Study identification
- NCT ID
- NCT06571045
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Lead sponsor
- EyeBiotech Ltd.
- Industry
- Enrollment
- 984 participants
Conditions and interventions
Conditions
Interventions
- EYE103 Drug
- Ranibizumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 6, 2024
- Primary completion
- Aug 31, 2026
- Completion
- Dec 30, 2027
- Last update posted
- Aug 11, 2025
2024 – 2027
United States locations
- U.S. sites
- 85
- U.S. states
- 28
- U.S. cities
- 81
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Scottsdale | Scottsdale | Arizona | 85255 | — |
| Fayetteville, Arkansas | Fayetteville | Arkansas | 72703 | — |
| Springdale, Arkansas | Springdale | Arkansas | 72764 | — |
| Bakersfield, CA | Bakersfield | California | 93309 | — |
| Glendale, CA | Glendale | California | 91204 | — |
| Modesto, CA | Modesto | California | 95356 | — |
| Mountain View, CA | Mountain View | California | 94040 | — |
| Redlands, CA | Redlands | California | 92374 | — |
| Sacramento, CA | Sacramento | California | 95825 | — |
| Sacramento, CA | Sacramento | California | 95841 | — |
| Santa Ana | Santa Ana | California | 92705 | — |
| Colorado Springs, CO | Colorado Springs | Colorado | 80909 | — |
| Denver, Colorado | Denver | Colorado | 80210 | — |
| Danbury, CT | Danbury | Connecticut | 06810 | — |
| Manchester, CT | Manchester | Connecticut | 06042 | — |
| Waterford,CT | Waterford | Connecticut | 06385 | — |
| Deerfield Beach, FL | Deerfield Beach | Florida | 33064 | — |
| Fort Lauderdale, FL | Fort Lauderdale | Florida | 33308 | — |
| Fort Myers,FL | Fort Myers | Florida | 33912 | — |
| Gainesville, FL | Gainesville | Florida | 32607 | — |
| Orlando, Florida | Orlando | Florida | 32806 | — |
| Plantation, FL | Plantation | Florida | 33324 | — |
| Sarasota, FL | Sarasota | Florida | 34232 | — |
| Saint Petersburg, FL | St. Petersburg | Florida | 33711 | — |
| Tallahassee, FL | Tallahassee | Florida | 32308 | — |
| Tampa, FL | Tampa | Florida | 33609-4614 | — |
| Tampa, FL | Tampa | Florida | 33617 | — |
| Winter Haven, FL | Winter Haven | Florida | 33880 | — |
| Lemont, IL | Lemont | Illinois | 60439 | — |
| Springfield, Illinois | Springfield | Illinois | 62702 | — |
| West Des Moines, IA | West Des Moines | Iowa | 50266 | — |
| Lenexa, Kansas | Lenexa | Kansas | 66215 | — |
| Wichita, Kansas | Wichita | Kansas | 67214 | — |
| Portland, Maine | Portland | Maine | 04101 | — |
| Hagerstown, MD | Hagerstown | Maryland | 21740 | — |
| Springfield,MA | Springfield | Massachusetts | 01107 | — |
| Grand Rapids, Michigan | Grand Rapids | Michigan | 49546 | — |
| Minneapolis, MN | Minneapolis | Minnesota | 55435 | — |
| Madison, MS | Madison | Mississippi | 39110 | — |
| Bloomfield, NJ | Bloomfield | New Jersey | 07003 | — |
| Cherry Hill, NJ | Cherry Hill | New Jersey | 08034 | — |
| Liverpool, NY | Liverpool | New York | 13088 | — |
| Oceanside, NY | Oceanside | New York | 11572 | — |
| Rochester, NY | Rochester | New York | 14620 | — |
| Asheville, NC | Asheville | North Carolina | 28803 | — |
| Hickory, NC | Hickory | North Carolina | 28602 | — |
| Wake Forest, MC | Wake Forest | North Carolina | 27587 | — |
| Winston Salem, NC | Winston-Salem | North Carolina | 27103 | — |
| Cleveland, Ohio | Cleveland | Ohio | 44122 | — |
| Cleveland, OH | Cleveland | Ohio | 44130 | — |
| Youngstown, Ohio | Youngstown | Ohio | 44505 | — |
| Edmond, OK | Edmond | Oklahoma | 73013 | — |
| Portland, OR | Portland | Oregon | 97221 | — |
| Springfield, Oregon | Springfield | Oregon | 97477 | — |
| Bethlehem, PA | Bethlehem | Pennsylvania | 18017 | — |
| Erie, PA | Erie | Pennsylvania | 16507 | — |
| Beaufort, SC | Beaufort | South Carolina | 29902 | — |
| Florence, SC | Florence | South Carolina | 29501 | — |
| Ladson, SC | Ladson | South Carolina | 29456 | — |
| West Columbia, SC | West Columbia | South Carolina | 29169 | — |
| Germantown, TN | Germantown | Tennessee | 38138 | — |
| Hixson, Tennessee | Hixson | Tennessee | 37343 | — |
| Johnson City, Tennessee | Johnson City | Tennessee | 37604 | — |
| Knoxville, TN | Knoxville | Tennessee | 37922 | — |
| Nashville, TN | Nashville | Tennessee | 37203 | — |
| Abilene, TX | Abilene | Texas | 79606 | — |
| Amarillo, TX | Amarillo | Texas | 79106 | — |
| Amarillo, TX | Amarillo | Texas | 79109 | — |
| Arlington, TX | Arlington | Texas | 76012 | — |
| Austin, TX | Austin | Texas | 78705 | — |
| Beaumont, TX | Beaumont | Texas | 77707 | — |
| Bellaire, TX | Bellaire | Texas | 77401 | — |
| Dallas, TX | Dallas | Texas | 75231 | — |
| Fort Worth, TX | Fort Worth | Texas | 76104 | — |
| Katy, TX | Katy | Texas | 77494 | — |
| Plano, TX | Plano | Texas | 75075 | — |
| Round Rock, TX | Round Rock | Texas | 78681 | — |
| San Antonio, TX | San Antonio | Texas | 78240 | — |
| Schertz, Texas | Schertz | Texas | 78154 | — |
| The Woodlands, TX | The Woodlands | Texas | 77384 | — |
| Willow Park, TX | Willow Park | Texas | 76087 | — |
| Salt Lake City, Utah | Salt Lake City | Utah | 84107 | — |
| Lynchburg, VA | Lynchburg | Virginia | 24502 | — |
| Richmond, Virginia | Richmond | Virginia | 23235 | — |
| Spokane, WA | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 98 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06571045, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 11, 2025 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06571045 live on ClinicalTrials.gov.