ASSESS ALL ALS Study
Public ClinicalTrials.gov record NCT06578195. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
ASSESS ALL ALS - Longitudinal Biomarker Study for Symptomatic ALS and Control Participants
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The ALL ALS Clinical Research Consortium is establishing research to collect a wide range of samples, clinical information and measurements from Amyotrophic Lateral Sclerosis (ALS) symptomatic, ALS gene carriers and control cohorts. This consortium is being funded by the National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS) and managed by two clinical coordinating centers (CCC) at Barrow Neurological Institute and Massachusetts General Hospital. The clinical sites are distributed across the country, and led by a group of collaborative principal investigators. Once data and samples are collected and harmonized, it will be made available to research community for future research into ALS and related neurological diseases. ASSESS protocol is specific for symptomatic ALS and control participants. This protocol includes both on-site and off-site(remote) participants. The participants will be followed for 24 months (2 years), and will include collection of medical history, clinical outcomes, and blood samples once in 4 months. Additionally, the participants will complete patient reported outcomes and speech recordings once a month. Participants who are coming into clinic may also provide optional Cerebrospinal Fluid (CSF) samples.
Study identification
- NCT ID
- NCT06578195
- Recruitment status
- Recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 2,000 participants
Conditions and interventions
Conditions
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 24, 2024
- Primary completion
- Jan 30, 2029
- Completion
- Jul 24, 2029
- Last update posted
- Aug 23, 2026
2024 – 2029
United States locations
- U.S. sites
- 36
- U.S. states
- 27
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Birmingham | Birmingham | Alabama | 35294 | Recruiting |
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | Recruiting |
| University of California, Irvine | Irvine | California | 92868 | Recruiting |
| University of California San Diego | La Jolla | California | 98037 | Recruiting |
| University of California, Los Angeles | Los Angeles | California | 90095 | Recruiting |
| University of California, San Francisco | San Francisco | California | 94143 | Recruiting |
| University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045 | Recruiting |
| Hospital For Special Care | New Britain | Connecticut | 06053 | Recruiting |
| Georgetown University | Washington D.C. | District of Columbia | 20007 | Recruiting |
| Nova Southeastern University | Davie | Florida | 33314 | Recruiting |
| Mayo Clinic | Jacksonville | Florida | 32224 | Recruiting |
| Saint Alphonsus Regional Medical Center | Boise | Idaho | 83704 | Recruiting |
| Northwestern University | Chicago | Illinois | 60611 | Recruiting |
| Synapticure (Remote Participation Only) | Chicago | Illinois | 60612 | Recruiting |
| Indiana University | Indianapolis | Indiana | 46202 | Recruiting |
| John Hopkins University | Baltimore | Maryland | 21205 | Recruiting |
| Nih/Ninds | Bethseda | Maryland | 20892 | Recruiting |
| Massachusetts General Brigham | Boston | Massachusetts | 02145 | Recruiting |
| University of Michigan | Ann Arbor | Michigan | 48109 | Recruiting |
| Henry Ford Health | Detroit | Michigan | 48202 | Recruiting |
| University of Minnesota | Minneapolis | Minnesota | 55455 | Recruiting |
| Washington University | St Louis | Missouri | 63110 | Recruiting |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | Recruiting |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | Recruiting |
| Columbia University | New York | New York | 10032 | Recruiting |
| Duke University | Durham | North Carolina | 27705 | Recruiting |
| Ohio State University | Colombus | Ohio | 43221 | Recruiting |
| Providence ALS Center | Portland | Oregon | 97213 | Recruiting |
| Penn State Health | Hershey | Pennsylvania | 17033 | Recruiting |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Temple University | Philadelphia | Pennsylvania | 19140 | Recruiting |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | Recruiting |
| Texas Neurology | Dallas | Texas | 75206 | Recruiting |
| University of Utah | Salt Lake City | Utah | 84132 | Recruiting |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | Recruiting |
| University of Washington | Seattle | Washington | 98195 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06578195, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 23, 2026 · Synced Sep 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06578195 live on ClinicalTrials.gov.