Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML
Public ClinicalTrials.gov record NCT06578247. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial Of Quizartinib Administered in Combination With Induction and Consolidation Chemotherapy and Administered as Maintenance Therapy in Adult Patients With Newly Diagnosed FLT3-ITD Negative Acute Myeloid Leukemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will compare the effects of Quizartinib versus placebo in combination with chemotherapy in participants with newly diagnosed FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication (ITD) negative acute myeloid leukemia (AML).
Study identification
- NCT ID
- NCT06578247
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 700 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 19, 2024 (Actual)
- Primary completion
- Jun 26, 2030 (Estimated)
- Completion
- Jun 26, 2030 (Estimated)
- Last update posted
- Jul 2, 2026
2024 – 2030
United States locations
- U.S. sites
- 52
- U.S. states
- 27
- U.S. cities
- 46
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope Phoenix | Goodyear | Arizona | 85338 | — |
| Mayo Clinic - Phoenix | Phoenix | Arizona | 85054 | — |
| University of Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| David Geffen School of Medicine | Los Angeles | California | 90095 | — |
| University of California Davis Health System | Sacramento | California | 95817 | — |
| Ucsf Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94115 | — |
| Stanford University School of Medicine- Parent | Stanford | California | 94305 | — |
| Colorado Blood Cancer Institute | Denver | Colorado | 80218 | — |
| Yale University | New Haven | Connecticut | 06510 | — |
| Sibley Memorial Hospital | Washington D.C. | District of Columbia | 20016 | — |
| Mayo Clinic Hospital | Jacksonville | Florida | 32224 | — |
| Florida Hospital Cancer Institute - Kissimmee | Kissimmee | Florida | 34741 | — |
| Tampa General Hospital | Tampa | Florida | 33606 | — |
| Moffitt Cancer Center | Tampa | Florida | 33612 | — |
| Winship Cancer Institute of Emory University | Atlanta | Georgia | 30322 | — |
| Augusta University | Augusta | Georgia | 30912 | — |
| Robert H Lurie Comprehensive Cancer Center Northwestern University | Chicago | Illinois | 60611 | — |
| University of Illinois Hospital & Health Sciences System | Chicago | Illinois | 60612 | — |
| The University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| University of Kentucky | Lexington | Kentucky | 40504 | — |
| Ochsner Medical Center - New Orleans | New Orleans | Louisiana | 70121 | — |
| Johns Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| University of Michigan Comprehensive Cancer Center Michigan Medicine | Ann Arbor | Michigan | 48109 | — |
| University of Minnesota Medical School - Twin Cities Campus | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic | Rochester | Minnesota | 55902 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Thomas Jefferson Univ Hosp | Haddonfield | New Jersey | 08033 | — |
| Roswell Park Comprehensive Cancer Center | Buffalo | New York | 14263 | — |
| Memorial Sloan Kettering Cancer Center - Main | Long Island City | New York | 11101 | — |
| Memorial Sloan Kettering Cancer Center - Main | New York | New York | 10065 | — |
| Upstate University Hospital | Syracuse | New York | 13210 | — |
| University of North Carolina Hospitals | Chapel Hill | North Carolina | 27514 | — |
| Duke Cancer Institute - Sarcoma Research | Durham | North Carolina | 27710 | — |
| University of Cincinnati | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195 | — |
| The James Cancer Hospital and Solove Research Institute | Columbus | Ohio | 43210 | — |
| Ohio Health Research Institute | Columbus | Ohio | 43214 | — |
| Peggy & Charles Stephenson Oklahoma Cancer Ctr | Oklahoma City | Oklahoma | 73104 | — |
| Oregon Health & Science University (Ohsu) | Portland | Oregon | 97239 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Upmc Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Tristar Bone Marrow Transplant | Nashville | Tennessee | 37203 | — |
| South Austin Medical Center | Austin | Texas | 78745 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| The University of Texas Md Anderson Cancer Center | Houston | Texas | 77030 | — |
| Uva Health System | Charlottesville | Virginia | 22908 | — |
| Virginia Commonwealth University (Vcu) Massey Cancer Center | Richmond | Virginia | 23229 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 232 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06578247, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 2, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06578247 live on ClinicalTrials.gov.