Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Moderate-to-Severe Plaque Psoriasis and Obesity or Overweight
Public ClinicalTrials.gov record NCT06588283. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of Ixekizumab or Ixekizumab Concomitantly Administered With Tirzepatide in Adult Participants With Moderate-to-Severe Plaque Psoriasis and Obesity or Overweight: A Phase 3b, Randomized, Multicenter, Open-Label Study (TOGETHER-PsO)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to demonstrate that when participants with moderate to severe plaque psoriasis and obesity or overweight in the presence of at least 1 weight-related comorbid condition receive ixekizumab and tirzepatide concomitantly administered, participants see improvement in their psoriasis and achieve weight reduction compared to when receiving ixekizumab. Participation in this study includes up to 12 visits and could last up to 61 weeks including screening, open label treatment period, and post-treatment follow-up period.
Study identification
- NCT ID
- NCT06588283
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 281 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 30, 2024 (Actual)
- Primary completion
- Jan 8, 2026 (Actual)
- Completion
- Jun 1, 2026 (Actual)
- Last update posted
- Jun 17, 2026
2024 – 2026
United States locations
- U.S. sites
- 68
- U.S. states
- 26
- U.S. cities
- 60
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Total Skin & Beauty Dermatology Center, PC DBA Total Dermatology | Birmingham | Alabama | 35203 | — |
| Medical Dermatology Specialists | Phoenix | Arizona | 85006 | — |
| Scottsdale Clinical Trials | Scottsdale | Arizona | 85260 | — |
| Yuma Clinical Trials | Yuma | Arizona | 85365 | — |
| Johnson Dermatology | Fort Smith | Arkansas | 72916 | — |
| California Dermatology & Clinical Research Institute | Encinitas | California | 92024 | — |
| First OC Dermatology Research Inc | Fountain Valley | California | 92708 | — |
| Avance Clinical Trials | Laguna Niguel | California | 92677 | — |
| Metropolis Dermatology | Los Angeles | California | 90017 | — |
| Dermatology Research Associates | Los Angeles | California | 90045 | — |
| Northridge Clinical Trials | Northridge | California | 91325 | — |
| Cura Clinical Research - Oxnard | Oxnard | California | 93030 | — |
| Integrative Skin Science and Research - Location 2 | Sacramento | California | 95815 | — |
| Therapeutics Clinical Research | San Diego | California | 92123 | — |
| Life Clinical Trials | Coral Springs | Florida | 33071 | — |
| Alliance for Multispecialty Research, LLC | Fort Myers | Florida | 33912 | — |
| NeoClinical Research | Hialeah | Florida | 33016 | — |
| Skin Care Research | Hollywood | Florida | 33021 | — |
| Encore Medical Research | Hollywood | Florida | 33024 | — |
| Solutions Through Advanced Research | Jacksonville | Florida | 32256 | — |
| Deluxe Health Center | Miami Lakes | Florida | 33014 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Leading Edge Dermatology | Plantation | Florida | 33317 | — |
| International Clinical Research - Sanford | Sanford | Florida | 32771 | — |
| Nodal Medical Center | Tampa | Florida | 33607 | — |
| Palm Harbor Dermatology PA d/b/a TrueBlue Clinical Research | Tampa | Florida | 33609 | — |
| DeNova Research | Chicago | Illinois | 60602 | — |
| Oak Dermatology | Naperville | Illinois | 60563 | — |
| Dawes Fretzin Clinical Research Group, LLC | Indianapolis | Indiana | 46250 | — |
| The Indiana Clinical Trials Center, PC | Plainfield | Indiana | 46168 | — |
| Equity Medical - Bowling Green | Bowling Green | Kentucky | 42104 | — |
| DelRicht Research | Baton Rouge | Louisiana | 70809 | — |
| Care Access - Lake Charles (Bayou Pines) | Lake Charles | Louisiana | 70601 | — |
| Dermatology and Skin Cancer Specialists, LLC | Rockville | Maryland | 20850 | — |
| Lawrence J. Green, MD, LLC | Rockville | Maryland | 20850 | — |
| Great Lakes Research Group, Inc. | Bay City | Michigan | 48706 | — |
| The Derm Institute of West Michigan | Caledonia | Michigan | 49316 | — |
| MI Skin Innovations | Northville | Michigan | 48167 | — |
| Las Vegas Dermatology | Las Vegas | Nevada | 89144 | — |
| Skin Cancer and Dermatology Institute - Reno | Reno | Nevada | 89509 | — |
| ActivMed Practices & Research, LLC. | Portsmouth | New Hampshire | 03801 | — |
| Psoriasis Treatment Center of Central New Jersey | East Windsor | New Jersey | 08520 | — |
| Care Access - Hoboken | Hoboken | New Jersey | 07030 | — |
| Equity Medical | New York | New York | 10023 | — |
| Mount Sinai Doctors - East 85th Street | New York | New York | 10028 | — |
| Onsite Clinical Solutions - Huntersville | Huntersville | North Carolina | 28078 | — |
| Red River Research Partners | Fargo | North Dakota | 58103 | — |
| Optima Research - Boardman | Boardman | Ohio | 44512 | — |
| Dermatologists of Southwest Ohio | Mason | Ohio | 45040 | — |
| Oregon Medical Research Center | Portland | Oregon | 97201 | — |
| Oregon Dermatology and Research Center | Portland | Oregon | 97210 | — |
| Dermatology Associates of Plymouth Meeting | Plymouth Meeting | Pennsylvania | 19462 | — |
| Columbia Dermatology & Aesthetics | Columbia | South Carolina | 29212 | — |
| International Clinical Research - Tennessee LLC | Murfreesboro | Tennessee | 37130 | — |
| DelRicht Research - Thompson's Station | Smyrna | Tennessee | 37167 | — |
| Tekton Research - Westlake Drive | Austin | Texas | 78746 | — |
| Bellaire Dermatology Associates | Bellaire | Texas | 77401 | — |
| Modern Research Associates, PLLC | Dallas | Texas | 75231 | — |
| Austin Institute for Clinical Research | Pflugerville | Texas | 78660 | — |
| Progressive Clinical Research | San Antonio | Texas | 78213 | — |
| Texas Dermatology and Laser Specialists | San Antonio | Texas | 78218 | — |
| Dermatology Clinical Research Center of San Antonio | San Antonio | Texas | 78229 | — |
| Tanner Clinic | Layton | Utah | 84041 | — |
| Care Access - Arlington | Arlington | Virginia | 22206 | — |
| Care Access - Danville | Danville | Virginia | 24541 | — |
| Virginia Clinical Research, Inc. | Norfolk | Virginia | 23502 | — |
| Bellevue Dermatology Clinic | Bellevue | Washington | 98004 | — |
| Dermatology of Seattle | Burien | Washington | 98168 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06588283, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 17, 2026 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06588283 live on ClinicalTrials.gov.