ClinicalTrials.gov record
A Study to Investigate the Safety and Efficacy of mRNA-1403 in Participants ≥18 Years of Age for the Prevention of Acute Gastroenteritis
ClinicalTrials.gov ID: NCT06592794
Public ClinicalTrials.gov record NCT06592794. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Observer-blinded, Placebo-controlled Study to Evaluate the Safety and Efficacy of mRNA-1403, a Multivalent Candidate Vaccine to Prevent Norovirus Acute Gastroenteritis in Adults ≥18 Years of Age
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objectives of this study are to evaluate the safety and reactogenicity of mRNA-1403, and to demonstrate the efficacy of mRNA-1403 to prevent protocol-defined moderate or severe norovirus acute gastroenteritis (AGE) associated with vaccine matched genotypes.
Study identification
- NCT ID
- NCT06592794
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 37,864 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 24, 2024 (Actual)
- Primary completion
- Feb 15, 2027 (Estimated)
- Completion
- Feb 15, 2027 (Estimated)
- Last update posted
- May 13, 2026
2024 – 2027
United States locations
- U.S. sites
- 184
- U.S. states
- 38
- U.S. cities
- 139
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Accel Research Sites - Achieve Clinical Research | Birmingham | Alabama | 32516 | — |
| Cullman Clinical Trials | Cullman | Alabama | 35055 | — |
| Alliance for Multispecialty Research, LLC | Daphne | Alabama | 36526 | — |
| ClinMed, LLC | Phoenix | Arizona | 85004 | — |
| DM Clinical - Phoenix | Phoenix | Arizona | 85012 | — |
| HOPE Research Institute | Phoenix | Arizona | 85018 | — |
| HOPE Research Institute | Phoenix | Arizona | 85023 | — |
| Abby's Research Institute | Phoenix | Arizona | 85031 | — |
| Headlands Research Scottsdale | Scottsdale | Arizona | 85260 | — |
| Scottsdale Clinical Trials | Scottsdale | Arizona | 85260 | — |
| Hope Research Institute - Tempe | Tempe | Arizona | 85284 | — |
| Arizona Liver Health | Tucson | Arizona | 85712 | — |
| Quality of Life Medical and Research Center | Tucson | Arizona | 85712 | — |
| Del Sol Research Management LLC.- Tucson | Tucson | Arizona | 85715 | — |
| Lynn Institute of the Ozarks | Little Rock | Arkansas | 72204 | — |
| Baptist Health Center for Clinical Research | Little Rock | Arkansas | 72205 | — |
| ARK Clinical Research, LLC | Fountain Valley | California | 92708 | — |
| ASCADA Research, LLC - Family Medicine | Fullerton | California | 92835 | — |
| Matrix Clinical Research | Huntington Park | California | 90255 | — |
| Velocity Clinical Research, San Diego | La Mesa | California | 91942 | — |
| Ark Clinical Research | Long Beach | California | 90815 | — |
| Matrix Clinical Research | Los Angeles | California | 90057 | — |
| Velocity Clinical Research - Westlake | Los Angeles | California | 90057 | — |
| Paradigm Research | Redding | California | 96001 | — |
| Artemis Institute for Clinical Research | Riverside | California | 92503 | — |
| Benchmark Research | Riverside | California | 92503 | — |
| Peninsula Research Associates (PRA) | Rolling Hills Estates | California | 90274 | — |
| Apex Clinical Research | San Diego | California | 92120 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92503 | — |
| Lynn Institute of Denver | Aurora | Colorado | 80012 | — |
| Tekton Research - Fort Collins | Fort Collins | Colorado | 80525 | — |
| Tekton Research, Inc - Longmont Center | Longmont | Colorado | 80501 | — |
| Imagine Research of Palm Beach County | Boynton Beach | Florida | 33435 | — |
| Pioneer Clinical Studies | Coral Gables | Florida | 33134 | — |
| Integrity Clinical Research, LLC (ICR SITES) - Doral | Doral | Florida | 33122 | — |
| Alliance for multispecialty Research - Florida | Doral | Florida | 33134 | — |
| AGA Clinical Trials | Hialeah | Florida | 33012 | — |
| Best Quality Research Inc. | Hialeah | Florida | 33016 | — |
| Neoclinical Research | Hialeah | Florida | 33016 | — |
| Research Centers of America | Hollywood | Florida | 33024 | — |
| Nature Coast Clinical Research, LLC - Inverness | Inverness | Florida | 34452 | — |
| Westside Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Clinical Neuroscience Solutions, Inc | Jacksonville | Florida | 32256 | — |
| Health Awareness INC | Jupiter | Florida | 33458 | — |
| University Clinical Research- Deland | Lake Mary | Florida | 32746 | — |
| Meridien Research | Lakeland | Florida | 33803 | — |
| Clinical Site Partners - Leesburg | Leesburg | Florida | 34748 | — |
| Accel Clinical Research - Maitland | Maitland | Florida | 32751 | — |
| Dade Research Center, LLC | Miami | Florida | 33126 | — |
| Miami Clinical Research | Miami | Florida | 33155 | — |
| Universal Axon Clinical Research | Miami | Florida | 33166 | — |
| Florida International Research Center | Miami | Florida | 33173 | — |
| Suncoast Research Associates, LLC | Miami | Florida | 33173 | — |
| Miami Dade Medical Research Institute, LLC | Miami | Florida | 33176 | — |
| Felicidad Medical Research | Miami | Florida | 33184 | — |
| Aqualane Clinical Research | Naples | Florida | 34105 | — |
| SUNCOAST Clinical Research | New Port Richey | Florida | 34652 | — |
| Clinical Neuroscience Solutions, Inc | Orlando | Florida | 32801 | — |
| Clinical Neuroscience Solutions, Inc | Orlando | Florida | 32806 | — |
| Clinical Research Center of Florida | Pompano Beach | Florida | 33060 | — |
| United Medical Research | Port Orange | Florida | 32127 | — |
| Health Awareness, Inc | Port Saint Lucie | Florida | 34952 | — |
| St. Johns Center for Clinical Research | Saint Augustine | Florida | 32086 | — |
| IMA Clinical Research - St. Petersburg | St. Petersburg | Florida | 33704 | — |
| Global Clinical Professionals, LLC | St. Petersburg | Florida | 33705 | — |
| Precision Clinical Research, LLC | Sunrise | Florida | 33351 | — |
| Albany Internal Medicine | Albany | Georgia | 31707 | — |
| Delricht Research At Springer Wellness And Restorative Health | Atlanta | Georgia | 30329 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| CenExel iResearch Atlanta, LLC | Decatur | Georgia | 30030 | — |
| Javara Inc. | Fayetteville | Georgia | 30214 | — |
| Fellows Research Alliance, Inc. | Savannah | Georgia | 31406 | — |
| Velocity Clinical Research-Savannah | Savannah | Georgia | 31406 | — |
| Clinical Research Atlanta/Headlands | Stockbridge | Georgia | 30281 | — |
| Clinical Research Prime | Idaho Falls | Idaho | 83404 | — |
| Velocity Clinical Research - Boise | Meridian | Idaho | 83642 | — |
| IMA Clinical Research | Chicago | Illinois | 60602 | — |
| Great Lakes Clinical Trials - Gurnee | Gurnee | Illinois | 60048 | — |
| Bioluminix Clinical Research Chicago | Naperville | Illinois | 60540 | — |
| Optimal Research | Peoria | Illinois | 61614 | — |
| DM Clinical Research- River Forest | River Forest | Illinois | 60305 | — |
| Velocity Clinical Research - Valparaiso | Valparaiso | Indiana | 46383 | — |
| Velocity Clinical Research-Sioux City | Sioux City | Iowa | 51106 | — |
| Johnson County Clin-Trials (JCCT) | Lenexa | Kansas | 66219 | — |
| Velocity Clinical Research- Kansas City | Overland Park | Kansas | 66210 | — |
| Tekton Research | Wichita | Kansas | 67218 | — |
| AMR Lexington | Lexington | Kentucky | 40509 | — |
| Velocity Clinical Research - Baton Rouge | Baton Rouge | Louisiana | 70809 | — |
| Velocity Clinical Research - Covington | Covington | Louisiana | 70433 | — |
| Benchmark Research | Metairie | Louisiana | 70006 | — |
| Clinical Trials Management, LLC | Metairie | Louisiana | 70006 | — |
| Privia Medical Group | Annapolis | Maryland | 27101 | — |
| Cenexel CBH (CBH Health) | Gaithersburg | Maryland | 20877 | — |
| Velocity Clinical Research-Rockville | Rockville | Maryland | 20854 | — |
| Javara Inc/Privia Medical Group, LLC | Silver Spring | Maryland | 20901 | — |
| DM Clinical Research - Brookline | Brookline | Massachusetts | 02445 | — |
| Skylight Health Research - Burlington | Burlington | Massachusetts | 02721 | — |
| Headlands Research - Detroit | Southfield | Michigan | 48034 | — |
| Great Lakes Research Institute | Southfield | Michigan | 48075 | — |
| DM Clinical Research - Southfield | Southfield | Michigan | 48076 | — |
| Oakland Medical Research Center | Troy | Michigan | 48085 | — |
| Clinical Research Institute, Inc. | Minneapolis | Minnesota | 55402 | — |
| Velocity Clinical Research, Gulfport | Gulfport | Mississippi | 39503 | — |
| Clinical Research Professionals | Chesterfield | Missouri | 63005 | — |
| Clinvest Headlands LLC | Springfield | Missouri | 65807 | — |
| Delricht Research | Springfield | Missouri | 65807 | — |
| Montana Medical Research, Inc | Missoula | Montana | 59808 | — |
| Velocity Clinical Research-Lincoln | Lincoln | Nebraska | 68510 | — |
| Velocity Clinical Research-Norfolk | Norfolk | Nebraska | 68701 | — |
| Velocity Clinical Research-Omaha | Omaha | Nebraska | 38134 | — |
| Javara Inc. / Nevada Health Centers, Ind | Carson City | Nevada | 89706 | — |
| Vector Clinical Trials | Las Vegas | Nevada | 89074 | — |
| Oasis Clinical Research | Las Vegas | Nevada | 89121 | — |
| DM Clinical Research - New Jersey | Jersey City | New Jersey | 07306 | — |
| IMA Clinical Research Warren | Warren Township | New Jersey | 07059 | — |
| Albuquerque Clinical Trials (ACT) | Albuquerque | New Mexico | 87102 | — |
| DM Clinical Research | Albuquerque | New Mexico | 87106 | — |
| Velocity Clinical Research- Albuquerque | Albuquerque | New Mexico | 87107 | — |
| Velocity Clinical Research - Binghamton | Binghamton | New York | 13905 | — |
| DM Clinical - Brooklyn | Brooklyn | New York | 11220 | — |
| Brooklyn Clinical Research | Brooklyn | New York | 11226 | — |
| Velocity Clinical Research - Syracuse | East Syracuse | New York | 13057 | — |
| Drug Trials America | Hartsdale | New York | 10530 | — |
| Rochester Clinical Research, Inc | Rochester | New York | 14609 | — |
| Velocity Clinical Research-Vestal | Vestal | New York | 13850 | — |
| DelRicht Research, LLC | Charlotte | North Carolina | 28205 | — |
| Javara Inc. - Tryon Medical-South Park | Charlotte | North Carolina | 28287 | — |
| Velocity Clinical Research, Durham | Durham | North Carolina | 27701 | — |
| West Clinical Research | Morehead City | North Carolina | 28557 | — |
| Accellacare Raleigh | Raleigh | North Carolina | 27609 | — |
| Accellacare of Wilmington | Wilmington | North Carolina | 28401 | — |
| Javara - Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27101 | — |
| Velocity Clinical Research, Cleveland | Beachwood | Ohio | 44122 | — |
| Velocity Clinical Research-Mt. Auburn | Cincinnati | Ohio | 45219 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45241 | — |
| Velocity Clinical Reseach - Blue Ash | Cincinnati | Ohio | 45242 | — |
| Velocity Clinical Research - Cincinnati OH | Cincinnati | Ohio | 45246 | — |
| Centricity Research | Columbus | Ohio | 43213 | — |
| Remington-Davis Clinical Research | Columbus | Ohio | 43215 | — |
| Tekton Research, Inc - Edmond | Edmond | Oklahoma | 73013 | — |
| Delricht Tate | Tulsa | Oklahoma | 74133 | — |
| Tekton Research, Inc - Yukon Location | Yukon | Oklahoma | 73099 | — |
| Altoona Center for Clinical Research - Research | Duncansville | Pennsylvania | 16635 | — |
| DM Clinical Research | Philadelphia | Pennsylvania | 19107 | — |
| Velocity Clinical Research - Providence | East Greenwich | Rhode Island | 02818 | — |
| Velocity Clinical Research - Anderson | Anderson | South Carolina | 29621 | — |
| DelRicht Research | Charleston | South Carolina | 29407 | — |
| Coastal Carolina Research Center - North Charleston | North Charleston | South Carolina | 29405 | — |
| Velocity Clinical Research, Spartanburg | Spartanburg | South Carolina | 29303 | — |
| PMG Research of Bristol, LLC | Bristol | Tennessee | 37620 | — |
| Delricht Moyer | Hendersonville | Tennessee | 37075 | — |
| CNS Healthcare DBA Clinical Neuroscience Solutions, INC | Memphis | Tennessee | 38119 | — |
| Benchmark Research | Austin | Texas | 78705 | — |
| IMA Clinical Research Austin | Austin | Texas | 78745 | — |
| Tekton Research, Inc. - Beaumont | Beaumont | Texas | 77706 | — |
| Headlands Research Brownsville | Brownsville | Texas | 78526 | — |
| Family Medicine Associates of Texas | Carrollton | Texas | 75010 | — |
| Javara Inc (Conroe) | Conroe | Texas | 77384 | — |
| WR-Global Medical Research, LLC | Dallas | Texas | 75224 | — |
| El Paso Research | El Paso | Texas | 79936 | — |
| Benchmark Research | Fort Worth | Texas | 76135 | — |
| West Houston Clinical Research Service | Houston | Texas | 77055 | — |
| DM Clinical Research - CyFair | Houston | Texas | 77065 | — |
| DM Clinical Research - Bellaire | Houston | Texas | 77081 | — |
| DM Clinical Research - Irving | Irving | Texas | 75061 | — |
| ACRC Trials | Plano | Texas | 75024 | — |
| Research Your Health | Plano | Texas | 75093 | — |
| Delricht Research At Zomnir Family Medicine | Prosper | Texas | 75078 | — |
| DM Clinical Research - San Antonio | San Antonio | Texas | 78207 | — |
| IMA Clinical Research | San Antonio | Texas | 78229 | — |
| Tekton Research Inc - San Antonio | San Antonio | Texas | 78229 | — |
| DM Clinical Research - Sugarland | Sugar Land | Texas | 77478 | — |
| DM Clinical Research - Tomball | Tomball | Texas | 77375 | — |
| DM Clinical Research | Tomball | Texas | 77375 | — |
| Cope Family Medicine | Bountiful | Utah | 84010 | — |
| JBR Clinical Research | Salt Lake City | Utah | 84107 | — |
| Charlottesville Medical Research Center, LLC | Charlottesville | Virginia | 22911 | — |
| Velocity Clinical Research - Hampton | Hampton | Virginia | 23666 | — |
| Health Research of Hampton Roads | Newport News | Virginia | 23606 | — |
| AMR Norfolk | Norfolk | Virginia | 37920 | — |
| Velocity Clinical Research-Portsmouth | Portsmouth | Virginia | 23703 | — |
| Clinical Research Partners, LLC | Richmond | Virginia | 23226 | — |
| DM Clinical Research - Seattle | Seattle | Washington | 98122 | — |
| Frontier Clinical Research, LLC | Kingwood | West Virginia | 26537 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 99 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06592794, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 13, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06592794 live on ClinicalTrials.gov.