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Completed Phase 2 Interventional

A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 Diabetes

ClinicalTrials.gov ID: NCT06603571

Public ClinicalTrials.gov record NCT06603571. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 31, 2026, 1:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Parallel-Group, Double-Blind, Placebo-Controlled Study to Investigate Weight Management With LY3841136 and Tirzepatide, Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 Diabetes

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The main purpose of this study, performed under the master protocol W8M-MC-CWMM (NCT06143956), is to investigate the safety and efficacy of LY3841136 for chronic weight management alone or in combination with Tirzepatide across a wide dose range in participants with Type 2 Diabetes. Participation in the study will last about 64 weeks.

Study identification

NCT ID
NCT06603571
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
367 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 20, 2024 (Actual)
Primary completion
Jul 1, 2026 (Actual)
Completion
Sep 14, 2026 (Actual)
Last update posted
Sep 29, 2026

2024 – 2026

United States locations

U.S. sites
48
U.S. states
20
U.S. cities
45
Facility City State ZIP Site status
The Institute for Liver Health II dba Arizona Clinical Trials - Mesa Chandler Arizona 85225 —
HOPE Research Institute Phoenix Arizona 85032 —
Headlands Research - Scottsdale Scottsdale Arizona 85260 —
The Institute for Liver Health II dba Arizona Liver Health-Tucson Tucson Arizona 85712 —
NorCal Medical Research, Inc Greenbrae California 94904 —
Velocity Clinical Research, Huntington Park Huntington Park California 90255 —
Peninsula Research Associates Rolling Hills Estates California 90274 —
Diablo Clinical Research, Inc. Walnut Creek California 94598 —
Stamford Therapeutics Consortium Stamford Connecticut 06905 —
Northeast Research Institute (NERI) Fleming Island Florida 32003 —
Indago Research & Health Center, Inc Hialeah Florida 33012 —
New Horizon Research Center Miami Florida 33165 —
Suncoast Clinical Research, Inc. New Port Richey Florida 34652 —
Charter Research - Winter Park Orlando Florida 32803 —
Charter Research - Lady Lake The Villages Florida 32162 —
Medical Research Partners Ammon Idaho 83406 —
Great Lakes Clinical Trials - Andersonville Chicago Illinois 60640 —
Great Lakes Clinical Trials - Ravenswood Chicago Illinois 60640 —
NorthShore University Health System Skokie Illinois 60077 —
Iowa Diabetes and Endocrinology Research Center West Des Moines Iowa 50266 —
Cotton O'Neil Diabetes & Endocrinology Topeka Kansas 66606 —
Knownwell Needham Massachusetts 02492 —
Lucida Clinical Trials New Bedford Massachusetts 02740 —
Headlands Research - Detroit Southfield Michigan 48034 —
Arcturus Healthcare , PLC, Troy Internal Medicine Research Division Troy Michigan 48098 —
StudyMetrix Research City of Saint Peters Missouri 63303 —
Clinvest Headlands Llc Springfield Missouri 65807 —
Las Vegas Medical Research Las Vegas Nevada 89128 —
Dent Neurologic Institute Amherst New York 14226 —
Velocity Clinical Research, Syracuse East Syracuse New York 13057 —
North Suffolk Neurology Port Jefferson Station New York 11776 —
Rochester Clinical Research, LLC Rochester New York 14609 —
Medication Management Greensboro North Carolina 27405 —
Monroe Biomedical Research Monroe North Carolina 28112 —
Lucas Research, Inc Morehead City North Carolina 28557 —
Lucas Research, Inc. New Bern North Carolina 28562 —
CTI Clinical Research Center Cincinnati Ohio 45212 —
Tribe Clinical Research, LLC Greenville South Carolina 29607 —
Quality Medical Research Nashville Tennessee 37211 —
IMA Clinical Research Austin Austin Texas 78745 —
Velocity Clinical Research, Dallas Dallas Texas 75230 —
FutureSearch Trials of Dallas Dallas Texas 75251 —
PlanIt Research, PLLC Houston Texas 77079 —
Tekton Research - Fredericksburg Road San Antonio Texas 78229 —
Endeavor Clinical Trials San Antonio Texas 78240 —
Texas Valley Clinical Research Weslaco Texas 78596 —
Spectrum Medical, Inc. Danville Virginia 24541 —
Central Washington Health Services Association d/b/a Confluence Health Wenatchee Washington 98801 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06603571, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 29, 2026 · Synced Oct 31, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT06603571 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →