A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)
Public ClinicalTrials.gov record NCT06615479. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Open-Label, Multicenter Study to Compare the Efficacy and Safety of Arlocabtagene Autoleucel (BMS-986393), a GPRC5D-directed CAR-T Cell Therapy, Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma
Study identification
- NCT ID
- NCT06615479
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
- Industry
- Enrollment
- 440 participants
Conditions and interventions
Interventions
- BMS-986393 Drug
- Carfilzomib Drug
- Cyclophosphamide Drug
- Daratumumab Drug
- Dexamethasone Drug
- Fludarabine Drug
- Pomalidomide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 11, 2025
- Primary completion
- Dec 29, 2027
- Completion
- Jun 21, 2032
- Last update posted
- Apr 13, 2026
2025 – 2032
United States locations
- U.S. sites
- 21
- U.S. states
- 16
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35205 | Recruiting |
| UCLA Hematology/Oncology - Santa Monica | Los Angeles | California | 90404 | Recruiting |
| Local Institution - 0050 | Orange | California | 92868 | Not yet recruiting |
| Local Institution - 0223 | Washington D.C. | District of Columbia | 20007 | Not yet recruiting |
| Baptist MD Anderson Cancer Center | Jacksonville | Florida | 32207 | Recruiting |
| University of Miami Hospital and Clinics, Sylvester Cancer Center | Miami | Florida | 33136 | Recruiting |
| Local Institution - 0228 | Orlando | Florida | 32803 | Not yet recruiting |
| Winship Cancer Institute, Emory University | Atlanta | Georgia | 30322 | Recruiting |
| Louisiana State University Health Sciences Shreveport | Shreveport | Louisiana | 71103 | Recruiting |
| Boston Medical Center | Boston | Massachusetts | 02118 | Recruiting |
| Local Institution - 0219 | Minneapolis | Minnesota | 55455 | Not yet recruiting |
| Local Institution - 0229 | New York | New York | 10065 | Not yet recruiting |
| Local Institution - 0221 | Stony Brook | New York | 11794 | Not yet recruiting |
| Levine Cancer Institute | Charlotte | North Carolina | 28204 | Recruiting |
| Cleveland Clinic | Cleveland | Ohio | 44195 | Recruiting |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | Recruiting |
| Local Institution - 0232 | Pittsburgh | Pennsylvania | 15224 | Not yet recruiting |
| Local Institution - 0227 | Charleston | South Carolina | 29425 | Not yet recruiting |
| Local Institution - 0184 | Houston | Texas | 77030 | Not yet recruiting |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | Recruiting |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 116 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06615479, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 13, 2026 · Synced May 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06615479 live on ClinicalTrials.gov.