Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral Neuropathy
Public ClinicalTrials.gov record NCT06619860. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-blind, Active-controlled, Dose-ranging, Parallel-design Study of the Efficacy and Safety of Oral VX-993 in Subjects With Pain Associated With Diabetic Peripheral Neuropathy
Study identification
- NCT ID
- NCT06619860
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Vertex Pharmaceuticals Incorporated
- Industry
- Enrollment
- 300 participants
Conditions and interventions
Conditions
Interventions
- Placebo (matched to VX-993) Drug
- Placebo (matched to pregabalin) Drug
- Pregabalin Drug
- VX-993 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 17, 2024
- Primary completion
- Apr 29, 2026
- Completion
- May 29, 2026
- Last update posted
- Apr 20, 2026
2024 – 2026
United States locations
- U.S. sites
- 25
- U.S. states
- 15
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cullman Clinical Trials | Cullman | Alabama | 35055 | Completed |
| Trovare Clinical Research - Bakersfield CA | Bakersfield | California | 93301 | Completed |
| Eximia Research - San Diego | La Mesa | California | 91942 | Completed |
| Paradigm Clincial Research Centers, LLC., Wheat Ridge | Wheat Ridge | Colorado | 80033 | Completed |
| Accel Research - Deland | DeLand | Florida | 32720 | Completed |
| AMR Fort Myers (The Clinical Study Center) | Fort Myers | Florida | 33912 | Completed |
| Velocity Clinical Research - Hallandale Beach | Hallandale | Florida | 33009 | Completed |
| Health Awareness, Inc., Jupiter | Jupiter | Florida | 33458 | Completed |
| Suncoast Research Associates - Miami | Miami | Florida | 33172 | Completed |
| Innovation Medical Research Center - Palmetto | Palmetto Bay | Florida | 33157 | Completed |
| Health Awareness, Inc. - Port St. Lucie | Port Saint Lucie | Florida | 34952 | Completed |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | Completed |
| Accel Research - Decatur | Decatur | Georgia | 30030 | Completed |
| Velocity Clinical Research - Boise | Meridian | Idaho | 83642 | Completed |
| Healthcare Research Network - Flossmoor IL | Flossmoor | Illinois | 604773027 | Completed |
| Quest Research Institute | Farmington Hills | Michigan | 48334 | Completed |
| Healthcare Research Network - Hazelwood MO | Hazelwood | Missouri | 63042 | Completed |
| Eximia Research - Raleigh | Raleigh | North Carolina | 27607 | Completed |
| Velocity Clinical Research - Cleveland | Beachwood | Ohio | 44122 | Completed |
| Velocity Clinical Research - Providence | East Greenwich | Rhode Island | 02818 | Completed |
| Clinical Trials of South Carolina - Berkeley - Moncks Corner | Moncks Corner | South Carolina | 29461 | Completed |
| Gadolin Research | Beaumont | Texas | 77702 | Completed |
| Velocity Clinical Research, Dallas | Dallas | Texas | 75230 | Completed |
| San Antonio Clinical Trials | San Antonio | Texas | 78240 | Completed |
| AMR Norfolk | Norfolk | Virginia | 23502 | Completed |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 22 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06619860, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 20, 2026 · Synced Apr 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06619860 live on ClinicalTrials.gov.