Quantification of Phosphorylated Alpha-synuclein in Cutaneous Biopsies as a Prospective Biomarker in Parkinson's Disease
Public ClinicalTrials.gov record NCT06621602. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study aims to assess the levels of phosphorylated alpha-synuclein (P-SYN) in patients with Parkinson's disease and REM Behavior Disorder using a minimally invasive skin punch biopsy. It seeks to understand the natural progression of P-SYN deposition over time to explore the potential of P-SYN quantification as a biomarker for disease progression.
Study identification
- NCT ID
- NCT06621602
- Recruitment status
- Active, not recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 100 participants
Conditions and interventions
Conditions
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 50 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 17, 2024 (Actual)
- Primary completion
- Apr 2027 (Estimated)
- Completion
- Apr 2027 (Estimated)
- Last update posted
- Oct 20, 2026
2024 – 2027
United States locations
- U.S. sites
- 18
- U.S. states
- 13
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| CND Life Sciences | Scottsdale | Arizona | 85258 | — |
| Movement Disorders Center of Arizona | Scottsdale | Arizona | 85258 | — |
| Parkinson's Research Centers of America - Orange County | Irvine | California | 92618 | — |
| Cedars Sinai | Los Angeles | California | 90048 | — |
| Parkinson's Research Centers of America - Palo Alto | Palo Alto | California | 94301 | — |
| University of Colorado | Aurora | Colorado | 80045 | — |
| Aventura Neurologic Associates, LLC | Aventura | Florida | 33180 | — |
| Parkinson's Disease and Movement Disorders Center - Boca Raton | Boca Raton | Florida | 33486 | — |
| Atlanta NeuroScience Institute ANI | Atlanta | Georgia | 30327 | — |
| Parkinson's Disease and Movement Disorders Center at KUMC | Kansas City | Kansas | 66160 | — |
| Neurology Multidisciplinary Clinic at Norton Healthcare | Louisville | Kentucky | 40241 | — |
| MedStar Montgomery Medical Center | Olney | Maryland | 20832 | — |
| Boston Neuro Research Center | Boston | Massachusetts | 02747 | — |
| Parkinson's Research Centers of America - Long Island | Commack | New York | 11725 | — |
| University of Rochester | Rochester | New York | 14618 | — |
| The Medical University of South Carolina | Charleston | South Carolina | 29403 | — |
| Veracity Neuroscience LLC | Memphis | Tennessee | 38157 | — |
| UT Health San Antonio | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06621602, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 20, 2026 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06621602 live on ClinicalTrials.gov.