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Recruiting Phase 3 Interventional

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

ClinicalTrials.gov ID: NCT06629779

Public ClinicalTrials.gov record NCT06629779. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 9, 2026, 1:06 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A PHASE 3, RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED STUDY OF PF-06821497 (MEVROMETOSTAT) WITH ENZALUTAMIDE IN METASTATIC CASTRATION RESISTANT PROSTATE CANCER (MEVPRO-2)

Study identification

NCT ID
NCT06629779
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Pfizer
Industry
Enrollment
900 participants

Conditions and interventions

Interventions

  • Enzalutamide Drug
  • PF-06821497 Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 21, 2024
Primary completion
Dec 1, 2026
Completion
Nov 29, 2028
Last update posted
May 4, 2026

2024 – 2028

United States locations

U.S. sites
44
U.S. states
11
U.S. cities
32
Facility City State ZIP Site status
Ironwood Cancer & Research Centers Chandler Arizona 85224 Recruiting
Ironwood Cancer & Research Centers Gilbert Arizona 85297 Recruiting
Palo Verde Hematology Oncology Glendale Arizona 85304 Recruiting
Ironwood Cancer & Research Centers Glendale Arizona 85306 Recruiting
Ironwood Cancer & Research Centers Goodyear Arizona 85395 Recruiting
Ironwood Cancer & Research Centers Mesa Arizona 85202 Recruiting
Ironwood Cancer & Research Centers Mesa Arizona 85206 Recruiting
Ironwood Cancer & Research Centers Phoenix Arizona 85028 Recruiting
Ironwood Cancer & Research Centers Scottsdale Arizona 85260 Recruiting
Highlands Oncology Fayetteville Arkansas 72703 Recruiting
Arkansas Urology - Little Rock Little Rock Arkansas 72211 Recruiting
Highlands Oncology Rogers Arkansas 72758 Recruiting
Highlands Oncology Group Springdale Arkansas 72762 Recruiting
Los Angeles Cancer Network (LACN) Anaheim California 92805 Recruiting
Los Angeles Cancer Network (LACN) Fountain Valley California 92708 Recruiting
Los Angeles Cancer Network (LACN) Glendale California 91204 Recruiting
Los Angeles Cancer Network (LACN) Glendale California 91206 Recruiting
Los Angeles Cancer Network (LACN) Laguna Hills California 92653 Recruiting
Los Angeles Cancer Network (LACN) Los Angeles California 90017 Recruiting
Los Angeles Cancer Network (LACN) Los Angeles California 90067 Recruiting
Medical Oncology Associates of San Diego San Diego California 92123 Recruiting
Accellacare of Duly Lisle Illinois 60532 Recruiting
Duly Health and Care (Bone Scintigraphy) Lisle Illinois 60532 Recruiting
Blessing Hospital Quincy Illinois 62301 Recruiting
Blessing Physician Services Quincy Illinois 62301 Recruiting
Duly Health and Care (CT and MRI) Westmont Illinois 60559 Recruiting
Adult & Pediatric Urology, PC Omaha Nebraska 68114 Recruiting
CHRISTUS St. Vincent Regional Cancer Center Santa Fe New Mexico 87505 Recruiting
Montefiore Medical Center - Medical Park The Bronx New York 10461 Recruiting
Montefiore Medical Center The Bronx New York 10467 Recruiting
Salisbury VA Medical Center Salisbury North Carolina 28144 Recruiting
AUC Urologists, LLC Myrtle Beach South Carolina 29572 Recruiting
Carolina Urologic Research Center, LLC Myrtle Beach South Carolina 29572 Recruiting
Grand Strand Medical Center Myrtle Beach South Carolina 29572 Recruiting
Parkway Surgery Center Myrtle Beach South Carolina 29572 Recruiting
USA Clinical Trials San Antonio Texas 78229 Recruiting
Northwest Medical Specialties, PLLC Bonney Lake Washington 98391 Recruiting
Northwest Medical Specialties, PLLC Federal Way Washington 98003 Recruiting
Northwest Medical Specialties, PLLC Gig Harbor Washington 98332 Recruiting
Northwest Medical Specialties, PLLC Puyallup Washington 98373 Recruiting
Harborview Medical Center Seattle Washington 98104 Recruiting
Fred Hutchinson Cancer Center Seattle Washington 98109 Recruiting
University of Washington Medical Center - Montlake Seattle Washington 98195 Recruiting
Northwest Medical Specialties, PLLC Tacoma Washington 98405 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 197 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06629779, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 4, 2026 · Synced May 9, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06629779 live on ClinicalTrials.gov.

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