ClinicalTrials.gov record
Recruiting Phase 1Phase 2 Interventional

A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

ClinicalTrials.gov ID: NCT06634589

Public ClinicalTrials.gov record NCT06634589. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 8, 2026, 10:44 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1b/2, Open-Label, Master Protocol Study of BTK-Degrader BGB-16673 in Combination With Other Agents in Patients With Relapsed or Refractory B-Cell Malignancies

Study identification

NCT ID
NCT06634589
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
BeOne Medicines
Industry
Enrollment
80 participants

Conditions and interventions

Interventions

  • BGB-16673 Drug
  • Glofitamab Drug
  • Mosunetuzumab Drug
  • Obinutuzumab Drug
  • Sonrotoclax Drug
  • Zanubrutinib Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 26, 2024
Primary completion
Dec 1, 2028
Completion
Dec 1, 2029
Last update posted
May 6, 2026

2024 – 2029

United States locations

U.S. sites
18
U.S. states
12
U.S. cities
15
Facility City State ZIP Site status
Mayo Clinic Phoenix Phoenix Arizona 85054-4502 Recruiting
University of Southern Californianorris Comprehensive Los Angeles California 90033 Recruiting
Mayo Clinic Jacksonville Jacksonville Florida 32224-1865 Recruiting
Moffitt Cancer Center Tampa Florida 33612-9496 Recruiting
The University of Kansas Cancer Center Westwood Kansas 66205-2003 Recruiting
Mayo Clinic Rochester Rochester Minnesota 55905-0001 Recruiting
Washington University School of Medicine St Louis Missouri 63110-1010 Recruiting
Summit Medical Group Florham Park New Jersey 07932-1049 Recruiting
Icahn School of Medicine At Mount Sinai New York New York 10029-6504 Recruiting
Columbia University Medical Center New York New York 10032 Recruiting
Weill Cornell Medical College Newyork Presbyterian Hospital New York New York 10065-4870 Recruiting
Memorial Sloan Kettering Cancer Center Mskcc New York New York 10065-6800 Recruiting
University of Rochester Rochester New York 14642-0001 Recruiting
Fox Chase Cancer Center Philadelphia Pennsylvania 19111-2434 Recruiting
The University of Texas Md Anderson Cancer Center Houston Texas 77030-4009 Recruiting
Huntsman Cancer Institute Salt Lake City Utah 84112-5550 Recruiting
University of Wisconsin Madison Wisconsin 53792-0001 Recruiting
Medical College of Wisconsin Milwaukee Wisconsin 53226-1222 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06634589, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 6, 2026 · Synced May 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06634589 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →