Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06)
Public ClinicalTrials.gov record NCT06635824. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective, Open-Label, Randomized, Phase 3 Trial of Acasunlimab (GEN1046) in Combination With Pembrolizumab Versus Docetaxel in Subjects With PD-L1 Positive Metastatic Non-Small Cell Lung Cancer After Treatment With a PD-1/PD-L1 Inhibitor and Platinum-Containing Chemotherapy (ABBIL1TY NSCLC-06)
Study identification
- NCT ID
- NCT06635824
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Genmab
- Industry
- Enrollment
- 191 participants
Conditions and interventions
Interventions
- Acasunlimab Drug
- Docetaxel Drug
- Pembrolizumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 24, 2024
- Primary completion
- Jul 29, 2027
- Completion
- Sep 29, 2028
- Last update posted
- May 4, 2026
2024 – 2028
United States locations
- U.S. sites
- 36
- U.S. states
- 18
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Blood and Cancer Specialists | Tucson | Arizona | 85712 | — |
| Usc Norris Comprehensive Cancer Center | Los Angeles | California | 90089 | — |
| Kaiser Permanente Vallejo Medical Center | Vallejo | California | 94589 | — |
| Ocala Oncology Center P.L. | Ocala | Florida | 34474 | — |
| Orlando Regional Medical Center | Orlando | Florida | 32806 | — |
| University Cancer & Blood Center, LLC | Athens | Georgia | 30607 | — |
| Piedmont Cancer Institute Atlanta | Atlanta | Georgia | 30318 | — |
| Piedmont Cancer Institute - Sandy Springs (Atlanta) Office | Atlanta | Georgia | 30328 | — |
| Piedmont Cancer Institute - Fayetteville Office | Fayetteville | Georgia | 30214 | — |
| Piedmont Cancer Institute - Newnan Office | Newnan | Georgia | 30265 | — |
| Piedmont Cancer Institute - Stockbridge Office | Stockbridge | Georgia | 30281 | — |
| Kaiser Foundation Hospitals | Honolulu | Hawaii | 96817 | — |
| University of Illinois | Chicago | Illinois | 60612 | — |
| Community Cancer Center East Medical Oncology Hematology | Indianapolis | Indiana | 46219 | — |
| Baptist Health Lexington | Lexington | Kentucky | 40503 | — |
| Norton Cancer Institute | Louisville | Kentucky | 40202 | — |
| Pikeville Medical Center | Pikeville | Kentucky | 41501 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| St. Francis Hospital - Grand Island | Grand Island | Nebraska | 68803 | — |
| Oncology Hematology West | Omaha | Nebraska | 68124 | — |
| Oncology Hematology West, PC dba Nebraska Cancer Specialists | Omaha | Nebraska | 68130 | — |
| Stony Brook University Medical Center|University Medical Center | Stony Brook | New York | 11790 | — |
| Novant Health Pharmacy | Charlotte | North Carolina | 28204 | — |
| Novant Health Oncology Specialists | Winston-Salem | North Carolina | 27103 | — |
| University of Pennsylvania Health System | Philadelphia | Pennsylvania | 19104 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | — |
| Parkridge Medical Center | Chattanooga | Tennessee | 37404 | — |
| University of Tennessee Medical Center Cancer Institute | Knoxville | Tennessee | 37920 | — |
| Midtown Tennessee Oncology | Nashville | Tennessee | 37203 | — |
| Tennessee Oncology | Nashville | Tennessee | 37205 | — |
| Texas Oncology-Austin Midtown | Austin | Texas | 78705 | — |
| Texas Oncology-Austin Central | Austin | Texas | 78731 | — |
| South Austin Cancer Ctr | Austin | Texas | 78745 | — |
| University of Virginia Hematology and Oncology | Charlottesville | Virginia | 22903 | — |
| Cancer Institute At Swedish Med Ctr | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 211 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06635824, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 4, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06635824 live on ClinicalTrials.gov.