ClinicalTrials.gov record
Active, not recruiting Phase 2 Interventional

A Study to Investigate Weight Management With Bimagrumab (LY3985863) and Tirzepatide (LY3298176), Alone or in Combination, in Adults With Obesity or Overweight

ClinicalTrials.gov ID: NCT06643728

Public ClinicalTrials.gov record NCT06643728. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 20, 2026, 7:29 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Double-Blind, Randomized, Placebo-Controlled Study of Bimagrumab and Tirzepatide, Alone or in Combination, to Investigate the Efficacy and Safety in Adult Participants With Obesity or Overweight Without Type 2 Diabetes

Study identification

NCT ID
NCT06643728
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
240 participants

Conditions and interventions

Interventions

  • Bimagrumab Drug
  • Bimagrumab Placebo Drug
  • Tirzepatide Drug
  • Tirzepatide Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 20, 2024
Primary completion
Mar 31, 2026
Completion
Dec 31, 2026
Last update posted
Sep 25, 2025

2024 – 2027

United States locations

U.S. sites
12
U.S. states
8
U.S. cities
12
Facility City State ZIP Site status
Pinnacle Research Group, LLC Anniston Alabama 36207
Central Research Associates Birmingham Alabama 35205
Diablo Clinical Research, Inc. Walnut Creek California 94598
Clinical Neuroscience Solutions, Inc. dba CNS Healthcare Jacksonville Florida 32256
Altus Research Lake Worth Florida 33461
Suncoast Research Group Miami Florida 33135
East-West Medical Research Institute Honolulu Hawaii 96814
Great Lakes Clinical Trials - Ravenswood Chicago Illinois 60640
SKY Integrative Medical Center/SKYCRNG Ridgeland Mississippi 39157
Keystone Clinical Studies Plymouth Meeting Pennsylvania 19462
Eastside Research Associates Redmond Washington 98052
Rainier Clinical Research Center Renton Washington 98057

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06643728, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 25, 2025 · Synced Apr 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06643728 live on ClinicalTrials.gov.

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