A Study to Investigate the Safety and Efficacy of TMP-301 Compared to Placebo in Adult Patients With Alcohol Use Disorder
Public ClinicalTrials.gov record NCT06648655. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Investigator and Participant bLInded, placeBo-controllEd, paRallel-group Study to Investigate the sAfety, Tolerability, and Preliminary Efficacy of TMP-301 TrEatment in Adult Patients With Alcohol Use Disorder (AUD)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
TMP-301 has been shown in preclinical models to reduce consumption of alcohol and other addictive substances. It has been tested in healthy subjects and has been found to be safe and tolerated at doses predicted to be efficacious in alcohol use disorder. This study is being conducted to evaluate the safety, tolerability and efficacy of TMP-301 in patients with alcohol use disorder.
Study identification
- NCT ID
- NCT06648655
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 110 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 14, 2024 (Actual)
- Primary completion
- Oct 13, 2025 (Actual)
- Completion
- Nov 14, 2025 (Actual)
- Last update posted
- Apr 13, 2026
2024 – 2025
United States locations
- U.S. sites
- 14
- U.S. states
- 10
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Headlands Research | Scottsdale | Arizona | 85260 | — |
| Yale School of Medicine | New Haven | Connecticut | 06511 | — |
| Research Centers of America, LLC | Hollywood | Florida | 33024 | — |
| CNS Healthcare- Jacksonville South | Jacksonville | Florida | 32256 | — |
| Segal Trials - West Broward Outpatient Site | Lauderhill | Florida | 33311 | — |
| CNS Healthcare | Orlando | Florida | 32801 | — |
| CenExcel iResearch | Decatur | Georgia | 30030 | — |
| CenExcel iResearch | Savannah | Georgia | 31405 | — |
| DelRicht Research - Murphy Clinic | Mandeville | Louisiana | 70448 | — |
| IMA Clinical Research | Albuquerque | New Mexico | 87109 | — |
| Neurobehavioral Research, Inc. | Cedarhurst | New York | 11516 | — |
| Medical University of South Carolina, Institute of Psychiatry | Charleston | South Carolina | 29425 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Virginia: Center for Leading Edge Addiction Research | Charlottesville | Virginia | 22903 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06648655, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 13, 2026 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06648655 live on ClinicalTrials.gov.