A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Public ClinicalTrials.gov record NCT06649110. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of LTP001 in Healthy Adult Participants (Part A) and to Evaluate the Efficacy and Safety of LTP001 for the Treatment of Participants With Pulmonary Arterial Hypertension (Part B)
Study identification
- NCT ID
- NCT06649110
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 232 participants
Conditions and interventions
Interventions
- LTP Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 100 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 23, 2024
- Primary completion
- Nov 28, 2028
- Completion
- Dec 30, 2028
- Last update posted
- Apr 28, 2026
2024 – 2028
United States locations
- U.S. sites
- 19
- U.S. states
- 15
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Pulmonary Specialists Ltd | Scottsdale | Arizona | 85258 | Recruiting |
| UC Irvine Medical Center | Orange | California | 92868-3298 | Recruiting |
| Stanford Medical Center | Stanford | California | 94305 | Recruiting |
| Univ Colorado Hospital | Aurora | Colorado | 80045 | Recruiting |
| Central Florida Pulmonary Group | Orlando | Florida | 32803-5734 | Recruiting |
| University of South Florida | Tampa | Florida | 33606-3475 | Recruiting |
| Emory University School of Medicine | Atlanta | Georgia | 30322 | Recruiting |
| U of Kansas Medical Center | Kansas City | Kansas | 66160 | Recruiting |
| Norton Infectious Diseases Specialists | Louisville | Kentucky | 40202 | Recruiting |
| Tufts Medical Center | Boston | Massachusetts | 02111 | Recruiting |
| Lahey Hospital and Medical Center | Burlington | Massachusetts | 01805 | Recruiting |
| Sky Integrative Medical Center SKYCRNG PPDS | Ridgeland | Mississippi | 39157-5179 | Recruiting |
| Summit Health Eastside Clinic | Bend | Oregon | 97701 | Recruiting |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212-4756 | Recruiting |
| Statcare Pulmonary Consultants | Knoxville | Tennessee | 37919 | Recruiting |
| PPD Development LP | Austin | Texas | 78744 | Recruiting |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | Recruiting |
| The University of Utah | Salt Lake City | Utah | 84132-0001 | Recruiting |
| Pul Ass Richmond Inc P A R | Richmond | Virginia | 23230-1709 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 66 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06649110, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 28, 2026 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06649110 live on ClinicalTrials.gov.