Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder

ClinicalTrials.gov ID: NCT06651177

Public ClinicalTrials.gov record NCT06651177. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 7:50 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

NIDA CTN-0152: Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder: A Pragmatic, Multi-site, Double-blind, Randomized, Placebo-controlled Trial (TAB)

Study identification

NCT ID: NCT06651177
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: T. John Winhusen, PhD; Other
Enrollment: 310 participants

Conditions and interventions

Conditions

Interventions

Placebo Other
Tirzepatide Drug

Other · Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jan 28, 2026
Primary completion: Sep 29, 2027
Completion: Oct 30, 2027
Last update posted: Mar 23, 2026

2026 – 2027

United States locations

U.S. sites: 10
U.S. states: 8
U.S. cities: 10

Facility	City	State	ZIP	Site status
Tarzana Treatment Centers	Tarzana	California	91356	Not yet recruiting
Gateway Community Services	Jacksonville	Florida	32204	Recruiting
IBIS Behavioral Health	Tampa	Florida	33605	Not yet recruiting
Ruth M. Rothstein CORE Center	Chicago	Illinois	60612	Recruiting
The Gibson Center for Behavioral Change	Cape Girardeau	Missouri	63703	Recruiting
Prisma Health	Greenville	South Carolina	29605	Recruiting
Vanderbilt University Medical Center	Nashville	Tennessee	37232	Recruiting
University of Utah	Salt Lake City	Utah	84108	Recruiting
Marshall Health	Huntington	West Virginia	25701	Recruiting
Healthy Minds/Chestnut Ridge	Morgantown	West Virginia	26505	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06651177, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Mar 23, 2026 · Synced May 8, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06651177 live on ClinicalTrials.gov.

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