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Active, not recruiting Not applicable Interventional

WATER IV Prostate Cancer

ClinicalTrials.gov ID: NCT06651632

Public ClinicalTrials.gov record NCT06651632. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 3:53 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

WATER IV Prostate Cancer: Aquablation Versus Radical Prostatectomy for the Treatment of Localized Prostate Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a multicenter, prospective, randomized clinical trial that aims to assess the safety and efficacy of Aquablation Therapy in men with low-risk to intermediate to high-risk localized prostate cancer who are candidates for, or have opted for, prostatectomy. Participants will be randomized to either Aquablation Therapy or radical prostatectomy and followed up to 10 years.

Study identification

NCT ID
NCT06651632
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Not applicable
Lead sponsor
PROCEPT BioRobotics
Industry
Enrollment
280 participants

Conditions and interventions

Interventions

Device · Procedure

Eligibility (public fields only)

Age range
45 Years and older
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 3, 2025 (Actual)
Primary completion
Jul 2027 (Estimated)
Completion
Jan 2037 (Estimated)
Last update posted
May 4, 2026

2025 – 2037

United States locations

U.S. sites
26
U.S. states
17
U.S. cities
25
Facility City State ZIP Site status
Arizona State Urological Institute Chandler Arizona 85224 —
East Valley Urology Center Mesa Arizona 85206 —
University of Southern California Los Angeles California 90089 —
Boulder Medical Center Boulder Colorado 80304 —
Advanced Research Delray Beach Florida 33484 —
University of Miami Miami Florida 33146 —
Florida Urology Partners Tampa Florida 33606 —
Trophy Point Urology Tampa Florida 33607 —
Georgia Urology Atlanta Georgia 30328 —
Mountain View Hospital Idaho Falls Idaho 83401 —
University of Chicago Chicago Illinois 60637 —
Endeavor Health Glenview Illinois 60026 —
Johns Hopkins University Baltimore Maryland 21287 —
Kansas City Urology Care North Kansas City Missouri 64116 —
Kearney Urology Center Kearney Nebraska 68847 —
Adult & Pediatric Urology Omaha Nebraska 68114 —
Hackensack University Medical Center Hackensack New Jersey 07601 —
Integrated Medical Professionals, PLLC New York New York 10016 —
University of Rochester Medical Center Rochester New York 14642 —
Cleveland Clinic Foundation Cleveland Ohio 44195 —
MUSC Hollings Cancer Center Charleston South Carolina 29425 —
Tidelands Health Urology Murrells Inlet South Carolina 29576 —
Urology Austin Austin Texas 78745 —
Urology Clinics of North Texas Dallas Texas 75231 —
Potomac Urology Alexandria Virginia 22311 —
Advocate Aurora Research Institute Sheboygan Wisconsin 53081 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06651632, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 4, 2026 · Synced Oct 22, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT06651632 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →