ALTO-100 in Bipolar Disorder With Depression (BD-D)
Public ClinicalTrials.gov record NCT06656416. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Study Followed by Open-Label Treatment of ALTO-100 in Adults With Bipolar Disorder Currently Experiencing a Major Depressive Episode
Study identification
- NCT ID
- NCT06656416
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Alto Neuroscience
- Industry
- Enrollment
- 200 participants
Conditions and interventions
Interventions
- ALTO-100 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 1, 2024
- Primary completion
- Jul 31, 2026
- Completion
- Sep 30, 2026
- Last update posted
- Jul 15, 2025
2024 – 2026
United States locations
- U.S. sites
- 27
- U.S. states
- 14
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Site 6036 | Chandler | Arizona | 85224 | Withdrawn |
| Site 6000 | Phoenix | Arizona | 85012 | Recruiting |
| Site 6087 | Yuma | Arizona | 85364 | Recruiting |
| 6039 | Fayetteville | Arkansas | 72703 | Recruiting |
| 6070 | Little Rock | Arkansas | 72204 | Recruiting |
| Site 6081 | Imperial | California | 92251 | Recruiting |
| 6069 | Los Angeles | California | 90025 | Recruiting |
| Site 6016 | Mather | California | 95655 | Not yet recruiting |
| Site 6082 | Oceanside | California | 92056 | Recruiting |
| Site 6102 | Riverside | California | 92506 | Recruiting |
| Site 6112 | Colorado Springs | Colorado | 80910 | Not yet recruiting |
| Site 6067 | Lauderhill | Florida | 33319 | Withdrawn |
| Site 6068 | Atlanta | Georgia | 30328 | Recruiting |
| Site 6064 | Peachtree Corners | Georgia | 30071 | Recruiting |
| Site 6151 | Baltimore | Maryland | 21229 | Withdrawn |
| Site 6076 | Bel Air | Maryland | 21015 | Recruiting |
| Site 6062 | Gaithersburg | Maryland | 20877 | Recruiting |
| Site 6142 | Lincoln | Nebraska | 68526 | Recruiting |
| Site 6144 | Las Vegas | Nevada | 89102 | Recruiting |
| Site 6104 | Las Vegas | Nevada | 89119 | Recruiting |
| Site 6066 | Toms River | New Jersey | 08755 | Recruiting |
| Site 6014 | Albuquerque | New Mexico | 87108 | Not yet recruiting |
| Site 6078 | Albuquerque | New Mexico | 87110 | Recruiting |
| 6065 | North Canton | Ohio | 44720 | Recruiting |
| Site 6075 | Westlake | Ohio | 44145 | Recruiting |
| Site 6072 | Houston | Texas | 77081 | Recruiting |
| Site 6121 | Draper | Utah | 84020 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06656416, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 15, 2025 · Synced May 19, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06656416 live on ClinicalTrials.gov.