A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors
Public ClinicalTrials.gov record NCT06657144. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1B, Multicenter, Open-Label Study of the Safety and Efficacy of CHS-114 in Combination With Toripalimab With or Without Other Treatments in Participants With Advanced or Metastatic Solid Tumors (TREGCHECK 102)
Study identification
- NCT ID
- NCT06657144
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Coherus Oncology, Inc.
- Industry
- Enrollment
- 154 participants
Conditions and interventions
Conditions
Interventions
- 5 Fluorouracil Drug
- CHS-114 Drug
- Cisplatin Drug
- Toripalimab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 31, 2025
- Primary completion
- Dec 31, 2027
- Completion
- Dec 31, 2027
- Last update posted
- Apr 5, 2026
2025 – 2028
United States locations
- U.S. sites
- 20
- U.S. states
- 15
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The University of Arizona Cancer Center | Tucson | Arizona | 85724 | Withdrawn |
| City of Hope | Duarte | California | 91010 | Recruiting |
| University of Colorado - Aurora Cancer Center | Aurora | Colorado | 80045 | Recruiting |
| Winship Cancer Center - Emory University | Atlanta | Georgia | 30322 | Recruiting |
| Ochsner Health | New Orleans | Louisiana | 70121 | Recruiting |
| Henry Ford Health System | Detroit | Michigan | 48202 | Recruiting |
| Comprehensive Cancer Center of Nevada | Las Vegas | Nevada | 89169 | Recruiting |
| Christus St Vincent Regional Medical Center | Santa Fe | New Mexico | 87505 | Recruiting |
| START New York | Lake Success | New York | 11042 | Recruiting |
| David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Recruiting |
| Icahn School of Medicine at Mount Sinai | New York | New York | 11766 | Recruiting |
| University of Pittsburg Medical Center _UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | Recruiting |
| Prisma Health Cancer Institute | Greenville | South Carolina | 29605 | Recruiting |
| SCRI Oncology Partners | Nashville | Tennessee | 37203 | Recruiting |
| Texas Oncology - Central South | Austin | Texas | 78731 | Recruiting |
| START San Antonio, LLC. | San Antonio | Texas | 78229 | Recruiting |
| Huntsman Cancer Institute, University of Utah | Salt Lake City | Utah | 84112 | Recruiting |
| START Mountain Region, LLC. | West Valley City | Utah | 84119 | Recruiting |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | Recruiting |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06657144, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 5, 2026 · Synced Apr 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06657144 live on ClinicalTrials.gov.