A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)
Public ClinicalTrials.gov record NCT06660394. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Investigate the Efficacy, Safety, and Tolerability of LP352 in the Treatment of Seizures in Children and Adults With Dravet Syndrome
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This (DEEp SEA Study) is a double-blind, randomized, placebo-controlled, multicenter study to investigate the efficacy, safety, and tolerability of LP352 in the treatment of seizures in children and adults with DS. The study consists of 3 main phases: Screening, Titration period, and Maintenance period, followed by a Taper period and Follow-Up. Participants will be randomized to LP352 or placebo. The total duration of the study will be approximately 24 months.
Study identification
- NCT ID
- NCT06660394
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 96 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 2 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 25, 2024 (Actual)
- Primary completion
- Dec 31, 2026 (Estimated)
- Completion
- Dec 31, 2026 (Estimated)
- Last update posted
- Sep 17, 2026
2024 – 2026
United States locations
- U.S. sites
- 25
- U.S. states
- 15
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arkansas Children's Hospital - Cardiology Clinic | Little Rock | Arkansas | 72202-3500 | — |
| Children's Hospital Los Angeles (CHLA) | Los Angeles | California | 90027-6062 | — |
| University of California Los Angeles (UCLA) - David Geffen School of Medicine - Global Health Pro... | Los Angeles | California | 90095 | — |
| Stanford University - Stanford School of Medicine - Pulmonary and Cystic Fibrosis Center | Palo Alto | California | 94304-1511 | — |
| UCSF Benioff Children's Hospitals - San Francisco | San Francisco | California | 94158 | — |
| Children's Hospital Colorado - Heart Institute | Aurora | Colorado | 80045-7106 | — |
| Children's National Hospital - Children's National Heart Center | Washington D.C. | District of Columbia | 20010-2916 | — |
| NW FL Clinical Research Group, LLC | Gulf Breeze | Florida | 32561-4495 | — |
| Nicklaus Children's Hospital (Miami Children's Hospital) | Miami | Florida | 33155-3009 | — |
| Research Institute of Orlando LLC | Orlando | Florida | 32806 | — |
| Pediatric Epilepsy & Neurology Specialists (PENS) | Tampa | Florida | 33609-4191 | — |
| Rare Disease Research, LLC. (RDR) | Atlanta | Georgia | 30329 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611-2908 | — |
| Northwestern University - Ann & Robert H. Lurie Children's Hospital of Chicago - Center for Cance... | Chicago | Illinois | 60611-2991 | — |
| Mid-Atlantic Epilepsy and Sleep Center - Bethesda | Bethesda | Maryland | 20817-1844 | — |
| Mayo Clinic - Children's Center - Rochester | Rochester | Minnesota | 55905-0001 | — |
| Barnabas Health - Institute of Neurology and Neurosurgery | Livingston | New Jersey | 07039-5817 | — |
| Northeast Regional Epilepsy Group - Morristown | Morristown | New Jersey | 07960-6092 | — |
| NYU Langone Health-NYU Comprehensive Epilepsy Center | New York | New York | 10016-4852 | — |
| Oregon Health & Science University - Blood Brain Barrier and Neuro-Oncology Program | Portland | Oregon | 97239-3098 | — |
| Le Bonheur Children's Hospital - Outpatient Center | Memphis | Tennessee | 38105-4625 | — |
| Child Neurology Consultants of Austin - Austin | Austin | Texas | 78731-3157 | — |
| Cook Children's Jane and John Justin Neurosciences Center | Fort Worth | Texas | 76104-2710 | — |
| The University of Texas Medical School at Houston - UT Gastroenterology | Houston | Texas | 77030-1517 | — |
| MultiCare Health System | Tacoma | Washington | 98415-0299 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 80 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06660394, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 17, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06660394 live on ClinicalTrials.gov.