A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)
Public ClinicalTrials.gov record NCT06660394. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Investigate the Efficacy, Safety, and Tolerability of LP352 in the Treatment of Seizures in Children and Adults With Dravet Syndrome
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This (DEEp SEA Study) is a double-blind, randomized, placebo-controlled, multicenter study to investigate the efficacy, safety, and tolerability of LP352 in the treatment of seizures in children and adults with DS. The study consists of 3 main phases: Screening, Titration period, and Maintenance period, followed by a Taper period and Follow-Up. Participants will be randomized to LP352 or placebo. The total duration of the study will be approximately 24 months.
Study identification
- NCT ID
- NCT06660394
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 104 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 2 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 24, 2024
- Primary completion
- Aug 20, 2026
- Completion
- Oct 1, 2026
- Last update posted
- Aug 9, 2026
2024 – 2026
United States locations
- U.S. sites
- 25
- U.S. states
- 15
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arkansas Children's Hospital - Cardiology Clinic | Little Rock | Arkansas | 72202-3500 | Recruiting |
| Children's Hospital Los Angeles - PIN | Los Angeles | California | 90027-6062 | Recruiting |
| David Geffen School of Medicine at UCLA | Los Angeles | California | 90095 | Recruiting |
| The Stanford Division of Child Neurology | Palo Alto | California | 94304-1510 | Recruiting |
| UCSF Benioff Children's Hospitals - San Francisco | San Francisco | California | 94158 | Completed |
| Children's Hospital Colorado. | Aurora | Colorado | 80045-7106 | Recruiting |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010 | Recruiting |
| NW FL Clinical Research Group, LLC | Gulf Breeze | Florida | 32561-4495 | Recruiting |
| Nicklaus Children's Hospital - PIN | Miami | Florida | 33155-3009 | Recruiting |
| Research Institute of Orlando LLC | Orlando | Florida | 32806 | Completed |
| Pediatric Epilepsy and Neurology Specialists | Tampa | Florida | 33609-4190 | Recruiting |
| Rare Disease Research, LLC - Atlanta - RDR - PIN | Atlanta | Georgia | 30329 | Completed |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611-2908 | Recruiting |
| Ann and Robert H Lurie Childrens Hospital of Chicago - PIN | Chicago | Illinois | 60611 | Recruiting |
| Mid-Atlantic Epilepsy and Sleep Center - Bethesda | Bethesda | Maryland | 20817-1844 | Recruiting |
| Mayo Clinic Children's - PIN | Rochester | Minnesota | 55905-0001 | Recruiting |
| Institute of Neurology and Neurosurgery at Saint Barnabas, LLC | Livingston | New Jersey | 07039-5817 | Recruiting |
| Northeast Regional Epilepsy Group - Morristown - 310 Madison Ave | Morristown | New Jersey | 07960 | Recruiting |
| NYU Langone Health-NYU Comprehensive Epilepsy Center | New York | New York | 10016-4852 | Recruiting |
| Oregon Health & Science University - Blood Brain Barrier and Neuro-Oncology Program | Portland | Oregon | 97239-3098 | Recruiting |
| Le Bonheur Childrens Outpatient Center - PIN | Memphis | Tennessee | 38103-2816 | Recruiting |
| Child Neurology Consultants of Austin - 6811 Austin Center Blvd | Austin | Texas | 78731-3157 | Recruiting |
| Cook Children's Jane and John Justin Neurosciences Center - PIN | Fort Worth | Texas | 76104 | Recruiting |
| The University of Texas Medical School at Houston - UT Gastroenterology | Houston | Texas | 77030-1517 | Recruiting |
| Multicare Health System - Mary Bridge Pediatrics | Tacoma | Washington | 98405-4048 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 79 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06660394, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 9, 2026 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06660394 live on ClinicalTrials.gov.