A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity
Public ClinicalTrials.gov record NCT06662383. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Retatrutide Compared to Tirzepatide in Adults Who Have Obesity
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to evaluate the efficacy and safety of retatrutide compared to tirzepatide in adults who have obesity. The study will last about 89 weeks.
Study identification
- NCT ID
- NCT06662383
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 800 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 1, 2024 (Actual)
- Primary completion
- Nov 2026 (Estimated)
- Completion
- Dec 2026 (Estimated)
- Last update posted
- Jul 20, 2026
2024 – 2026
United States locations
- U.S. sites
- 40
- U.S. states
- 22
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Medical Advancement Centers of Arizona | Tempe | Arizona | 85283 | — |
| Mary & Dick Allen Diabetes Center | Newport Beach | California | 92663 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92103 | — |
| Encompass Clinical Research | Spring Valley | California | 91978 | — |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | — |
| Lynn Institute of Denver | Aurora | Colorado | 80012 | — |
| Bridgeport Hospital | Bridgeport | Connecticut | 06610 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06519 | — |
| Encore Medical Research | Hollywood | Florida | 33024 | — |
| Suncoast Research Group | Miami | Florida | 33135 | — |
| Onhealth Research Center | Miami | Florida | 33186 | — |
| Precision Clinical Research | Sunrise | Florida | 33351 | — |
| Einstein Clinical Research | Vero Beach | Florida | 32960 | — |
| ClinCept Clinical Research - MH | Columbus | Georgia | 31904 | — |
| Northeast Georgia Medical Center | Gainesville | Georgia | 30501 | — |
| Pivotal Research Solutions | Stonecrest | Georgia | 30038 | — |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Integrated Clinical Trial Services, Inc. | West Des Moines | Iowa | 50265 | — |
| Pennington Biomedical Research Center | Baton Rouge | Louisiana | 70808 | — |
| Great Lakes Research Group, Inc. | Bay City | Michigan | 48706 | — |
| Great Lakes Research Institute | Southfield | Michigan | 48075 | — |
| StudyMetrix Research | City of Saint Peters | Missouri | 63303 | — |
| Las Vegas Endocrinology | Henderson | Nevada | 89074 | — |
| Albany Medical College, Division of Community Endocrinology | Albany | New York | 12203 | — |
| New York Gastroenterology Associates | New York | New York | 10075 | — |
| Westchester Medical Center | Valhalla | New York | 10595 | — |
| PharmQuest Life Sciences, LLC | Greensboro | North Carolina | 27408 | — |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | — |
| Accellacare - Wilmington | Wilmington | North Carolina | 28401 | — |
| Lillestol Research | Fargo | North Dakota | 58104 | — |
| PriMED Clinical Research | Dayton | Ohio | 45429 | — |
| Tribe Clinical Research, LLC | Greenville | South Carolina | 29607 | — |
| WR-Clinsearch, LLC | Chattanooga | Tennessee | 37421 | — |
| Headlands Horizons LLC | Brownsville | Texas | 78526 | — |
| Next Level Urgent Care | Houston | Texas | 77057 | — |
| Houston Research Institute | Houston | Texas | 77079 | — |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | — |
| Chrysalis Clinical Research | St. George | Utah | 84790 | — |
| Charlottesville Medical Research | Charlottesville | Virginia | 22911 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 25 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06662383, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 20, 2026 · Synced Oct 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06662383 live on ClinicalTrials.gov.