ClinicalTrials.gov record
A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)
ClinicalTrials.gov ID: NCT06667700
Public ClinicalTrials.gov record NCT06667700. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 5, 2026, 7:06 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Placebo-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of Molnupiravir (MK-4482) in Non-Hospitalized Adults With COVID-19 at High Risk for Disease Progression
Study identification
- NCT ID
- NCT06667700
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Merck Sharp & Dohme LLC
- Industry
- Enrollment
- 3,082 participants
Conditions and interventions
Conditions
Interventions
- Molnupiravir Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 1, 2024
- Primary completion
- Jan 25, 2031
- Completion
- Jan 25, 2031
- Last update posted
- Apr 22, 2026
2024 – 2031
United States locations
- U.S. sites
- 71
- U.S. states
- 24
- U.S. cities
- 62
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cullman Clinical Trials ( Site 3813) | Cullman | Alabama | 35055 | Completed |
| Helios Clinical Research ( Site 3826) | Paradise Valley | Arizona | 85253 | Recruiting |
| Absolute Clinical Research ( Site 3709) | Phoenix | Arizona | 85051 | Recruiting |
| Clinica de Salud del Valle de Salinas ( Site 3825) | Castroville | California | 95012 | Recruiting |
| Ascada Health PC dba Ascada Research ( Site 3750) | Fullerton | California | 92835 | Completed |
| Pacific Clinical Studies ( Site 3827) | Los Alamitos | California | 90720 | Recruiting |
| Valley Clinical Trials, Inc. ( Site 3707) | Northridge | California | 91325 | Recruiting |
| FOMAT Medical Research ( Site 3720) | Oxnard | California | 93030 | Recruiting |
| Paradigm Clinical Research, LLC ( Site 3785) | San Diego | California | 91208 | Recruiting |
| Optimus Medical ( Site 3817) | San Francisco | California | 94102 | Recruiting |
| Millennium Clinical Trials ( Site 3758) | Westlake Village | California | 91361 | Recruiting |
| Paradigm Clinical Research Centers, Inc ( Site 3718) | Wheat Ridge | Colorado | 80033 | Recruiting |
| Encore Medical Research of Boynton Beach ( Site 3701) | Boynton Beach | Florida | 33436 | Recruiting |
| Prestige Clinical Research Center ( Site 3722) | Coral Gables | Florida | 33134 | Recruiting |
| Indago Research & Health Center, Inc ( Site 3714) | Hialeah | Florida | 33012 | Recruiting |
| Prestige Clinical Research ( Site 3830) | Homestead | Florida | 33030 | Recruiting |
| Accel Research Sites Network - St. Pete-Largo Clinical Research Unit ( Site 3779) | Largo | Florida | 33777 | Recruiting |
| Clinical Site Partners, LLC dba Flourish Research ( Site 3717) | Leesburg | Florida | 34748 | Recruiting |
| Advanced Pulmonary Research Institute ( Site 3781) | Loxahatchee Groves | Florida | 33470 | Recruiting |
| Southern Clinical Research ( Site 3773) | Miami | Florida | 33125 | Recruiting |
| Florida Pharmaceutical Research and Associates ( Site 3763) | Miami | Florida | 33143 | Recruiting |
| Bio-Medical Research LLC ( Site 3804) | Miami | Florida | 33144 | Recruiting |
| Bright Research Center ( Site 3746) | Miami | Florida | 33144 | Completed |
| Miami Clinical Research ( Site 3729) | Miami | Florida | 33155 | Recruiting |
| Reed Medical Research ( Site 3761) | Miami | Florida | 33176 | Recruiting |
| Palm Springs Community Health Center ( Site 3757) | Miami Lakes | Florida | 33014 | Recruiting |
| Panax Clinical Research ( Site 3803) | Miami Lakes | Florida | 33014 | Recruiting |
| Combined Research Orlando Phase I-IV ( Site 3797) | Orlando | Florida | 32807 | Recruiting |
| CDC Research Institute ( Site 3716) | Port Saint Lucie | Florida | 34952 | Recruiting |
| New Tampa Health ( Site 3764) | Tampa | Florida | 33603 | Recruiting |
| Clinical Research Trials of Florida ( Site 3703) | Tampa | Florida | 33607 | Recruiting |
| Precision Research Center ( Site 3704) | Tampa | Florida | 33614 | Recruiting |
| Encore Medical Research - Weston ( Site 3708) | Weston | Florida | 33331 | Active, not recruiting |
| Balanced Life Health Care Solutions/SKYCRNG ( Site 3713) | Lawrenceville | Georgia | 30046 | Recruiting |
| Renew Health Clinical Research ( Site 3760) | Snellville | Georgia | 30078 | Recruiting |
| Rophe Adult and Pediatric Medicine/SKYCRNG ( Site 3816) | Union City | Georgia | 30291 | Completed |
| Paradigm Clinical Research - Boise ( Site 3841) | Boise | Idaho | 83709 | Recruiting |
| Rush University Medical Center ( Site 3748) | Chicago | Illinois | 60612 | Recruiting |
| Duly Health and Care ( Site 3799) | Lombard | Illinois | 60148 | Recruiting |
| University of Louisville School of Medicine ( Site 3706) | Louisville | Kentucky | 40202 | Recruiting |
| Barnum Medical Research ( Site 3828) | Natchitoches | Louisiana | 71457 | Completed |
| Annapolis Internal Medicine - CCT Research ( Site 3700) | Annapolis | Maryland | 21401 | Recruiting |
| Kur Research - Columbia Medical ( Site 3767) | Columbia | Maryland | 21045 | Recruiting |
| Revival Research Institute, LLC ( Site 3835) | Dearborn | Michigan | 48126 | Completed |
| Michigan Center of Medical Research (MICHMER) ( Site 3734) | Farmington Hills | Michigan | 48334 | Recruiting |
| Henry Ford St John TM Center for Infectious Disease Research ( Site 3766) | Grosse Pointe Woods | Michigan | 48236 | Recruiting |
| Mankato Clinic ( Site 3842) | Mankato | Minnesota | 56001 | Recruiting |
| Prime Health and Wellness/SKYCRNG ( Site 3726) | Fayette | Mississippi | 39069 | Recruiting |
| SKY Integrative Medical Center/SKYCRNG ( Site 3740) | Ridgeland | Mississippi | 39157 | Recruiting |
| Nevada Health Centers ( Site 3840) | Carson City | Nevada | 89706 | Recruiting |
| WR-CRCN, LLC ( Site 3818) | Las Vegas | Nevada | 89106 | Recruiting |
| Saint Michael's Medical Center ( Site 3808) | Newark | New Jersey | 07102 | Recruiting |
| Holy Name Medical Center ( Site 3807) | Teaneck | New Jersey | 07666 | Recruiting |
| Weill Cornell Medical College ( Site 3814) | New York | New York | 10065 | Recruiting |
| Prime Global Research ( Site 3731) | The Bronx | New York | 10456 | Recruiting |
| OnSite Clinical Solutions ( Site 3784) | Charlotte | North Carolina | 28277 | Recruiting |
| Monroe Biomedical Research ( Site 3732) | Monroe | North Carolina | 28112 | Recruiting |
| IMA Clinical Research Mount Airy ( Site 3745) | Mount Airy | North Carolina | 27030 | Recruiting |
| Research Innovations, LLC ( Site 3712) | Beavercreek | Ohio | 45431 | Recruiting |
| Midlands Neurology & Pain Associates ( Site 3751) | Columbia | South Carolina | 29205 | Active, not recruiting |
| Helios Clinical Research - JAC ( Site 3833) | Jackson | Tennessee | 38305 | Recruiting |
| Javara - Privia Medical Group Gulf Coast - The Woodlands HWH ( Site 3837) | Conroe | Texas | 77384 | Recruiting |
| South Texas Clinical Research ( Site 3815) | Corpus Christi | Texas | 78404 | Recruiting |
| Care United Research, LLC ( Site 3747) | Forney | Texas | 75126 | Recruiting |
| Houston Methodist Hospital ( Site 3800) | Houston | Texas | 77030 | Recruiting |
| MD Anderson ( Site 3843) | Houston | Texas | 77030 | Recruiting |
| Andres Garcia Zuniga, M.D., P.A. ( Site 3782) | Laredo | Texas | 78041 | Recruiting |
| LinQ Research ( Site 3824) | Pearland | Texas | 77584 | Recruiting |
| Crossroads Clinical Research-Family Practice ( Site 3739) | Victoria | Texas | 77901 | Recruiting |
| Velocity Clinical Research - Hampton ( Site 3744) | Hampton | Virginia | 23666 | Recruiting |
| Eastside Research Associates ( Site 3727) | Redmond | Washington | 98052 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 151 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06667700, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 22, 2026 · Synced May 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06667700 live on ClinicalTrials.gov.