ClinicalTrials.gov record
A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUGANO) Primary Efficacy Will be Determined at Week 56
ClinicalTrials.gov ID: NCT06668064
Public ClinicalTrials.gov record NCT06668064. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 5, 2026, 1:39 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 2-year Phase 3, Multicenter, Prospective, Randomized, Double-Masked, Parallel-Group Study of EYP-1901, a Tyrosine Kinase Inhibitor (TKI), Compared to Aflibercept in Subjects With Wet AMD
Study identification
- NCT ID
- NCT06668064
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- EyePoint Pharmaceuticals, Inc.
- Industry
- Enrollment
- 400 participants
Conditions and interventions
Conditions
Interventions
- Aflibercept (2.0 mg) Drug
- EYP-1901 Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 21, 2024
- Primary completion
- Jul 31, 2026
- Completion
- Jul 31, 2027
- Last update posted
- May 3, 2026
2024 – 2027
United States locations
- U.S. sites
- 76
- U.S. states
- 31
- U.S. cities
- 73
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retinal Research Institute, LLC | Phoenix | Arizona | 85053 | — |
| Retina Partners of Northwest Arkansas | Springdale | Arkansas | 72764 | — |
| California Retina Consultants | Bakersfield | California | 93309 | — |
| Retina Vitreous Associates Medical Group | Beverly Hills | California | 90211 | — |
| Macula and Retina Institute | Glendale | California | 91203 | — |
| Retina Consultants San Diego | Poway | California | 92064 | — |
| Retina Consultants of Southern California | Redlands | California | 92374 | — |
| Retinal Consultants Medical Group | Sacramento | California | 95841 | — |
| Bay Area Retina Associates | Walnut Creek | California | 94598 | — |
| American Institute of Research | Whittier | California | 95008 | — |
| RSC Research, PLLC | Denver | Colorado | 80210 | — |
| Eye Center of Northern Colorado, PC | Fort Collins | Colorado | 80528 | — |
| Advanced Vision Institute | Longmont | Colorado | 80503 | — |
| Connecticut Eye Consultants, P.C. | Danbury | Connecticut | 06810 | — |
| SightSera Clinical Research LLC | Greenwich | Connecticut | 06830 | — |
| Retina Group of New England, PC | Waterford | Connecticut | 06385 | — |
| Advanced Research, LLC | Deerfield Beach | Florida | 33064 | — |
| Florida Retina Consultants | Lakeland | Florida | 33805 | — |
| Florida Retina Institute | Orlando | Florida | 32806 | — |
| Retina Specialty Institute | Pensacola | Florida | 32503 | — |
| Eye Associates of Pinellas | Pinellas Park | Florida | 33782 | — |
| MedEye Associates | South Miami | Florida | 33143 | — |
| Retina Specialists of Tampa | Tampa | Florida | 33544 | — |
| Retina Vitreous Associates of Florida | Tampa | Florida | 33617 | — |
| Center for Retina & Macular Disease | Winter Haven | Florida | 33880 | — |
| Gerogia Retina | Marietta | Georgia | 30060 | — |
| Retina Consultants of Hawaii | ‘Aiea | Hawaii | 96701 | — |
| Retina Associates | Elmhurst | Illinois | 60126 | — |
| University Retina and Macula Associates | Lemont | Illinois | 60439 | — |
| Midwest Eye Institute | Carmel | Indiana | 46290 | — |
| Retina Associates LLC | Lenexa | Kansas | 66215 | — |
| Maine Eye Center | Portland | Maine | 04101 | — |
| The Retina Care Center | Baltimore | Maryland | 21209 | — |
| Retina Groups of Washington | Chevy Chase | Maryland | 20815 | — |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | — |
| Retina Specialists | Towson | Maryland | 21204 | — |
| Ophthalmic Consultants of Boston OCB - Boston | Boston | Massachusetts | 02114 | — |
| New England Retina Consultants | Springfield | Massachusetts | 01107 | — |
| Retina Associates of Michigan | Grand Blanc | Michigan | 48439 | — |
| Foundation for Vision Research | Grand Rapids | Michigan | 49546 | — |
| Deep Blue Retina Clinical Research PLLC | Southaven | Mississippi | 38671 | — |
| The Retina Institute | St Louis | Missouri | 63128 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| NJ Retina | Teaneck | New Jersey | 07666 | — |
| NJ Retina | Toms River | New Jersey | 08755 | — |
| Vision Research Center at Eye Associates of New Mexico | Albuquerque | New Mexico | 87109 | — |
| Retina Vitreous Surgeons of CNY, PC | Liverpool | New York | 13088 | — |
| Retina Associates of Western NY, PC | Rochester | New York | 14620 | — |
| Retina Consultants PLLC | Slingerlands | New York | 12159 | — |
| Western Carolina Retinal Associates, PA | Asheville | North Carolina | 28803 | — |
| Cape Fear Retinal Associates, PC | Wilmington | North Carolina | 28401 | — |
| Piedmont Retina Specialists, P.A. - Winston-Salem Office | Winston-Salem | North Carolina | 27103 | — |
| Tulsa Retina Consultant | Tulsa | Oklahoma | 74114 | — |
| Verum Research LLC | Eugene | Oregon | 97401 | — |
| Erie Retina Research | Erie | Pennsylvania | 16507 | — |
| Eye Care Specialists - Kingston Location | Kingston | Pennsylvania | 18704 | — |
| Retina Consultants | Charleston | South Carolina | 29414 | — |
| Palmetto Retina Center | Florence | South Carolina | 29169 | — |
| Retina Consultants of Carolina P.A | Greenville | South Carolina | 29605 | — |
| Charles Retina Institute | Germantown | Tennessee | 38138 | — |
| Retina Research Institute of Texas Integrated Clinical Research | Abilene | Texas | 79606 | — |
| Retina and Vitreous of Texas | Bellaire | Texas | 77401 | — |
| Retina Consultants of Texas (Retina Consultants of Houston) - Woodlands | Bellaire | Texas | 77401 | — |
| Texas Retina Associates | Dallas | Texas | 75231 | — |
| Texas Retina Associates | Plano | Texas | 75075 | — |
| San Antonio Eye Center | San Antonio | Texas | 78215 | — |
| Retinal Consultants of Texas | San Antonio | Texas | 78240 | — |
| Retina Consultants of Texas | The Woodlands | Texas | 77384 | — |
| Tyler Retina Consultants | Tyler | Texas | 75703 | — |
| Strategic Clinical Research Group, LLC | Willow Park | Texas | 76087 | — |
| Retina Associates of Utah | Salt Lake City | Utah | 84107 | — |
| Salt Lake Retina | West Jordan | Utah | 84088 | — |
| The Retina Group of Washington | Fairfax | Virginia | 22031 | — |
| Piedmont Eye Center | Lynchburg | Virginia | 24502 | — |
| Retina Associates, P.C. | Winchester | Virginia | 22601 | — |
| University of Wisconsin School of Medicine and Public Health (UWSMPH) | Madison | Wisconsin | 53705 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06668064, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 3, 2026 · Synced May 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06668064 live on ClinicalTrials.gov.